Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Anna Rita, Migliaccio"'
Autor:
Anna Rita Migliaccio
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/750128ba3a6f4a22ab4bb8b7cd311205
Autor:
Anna Rita Migliaccio
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 408 (2024)
The identification of the hormone erythropoietin (EPO), which regulates red blood cell production, and its development into a pharmaceutical-grade product to treat anemia has been not only a herculean task but it has also been the first of its kind.
Externí odkaz:
https://doaj.org/article/c92b8763c68a4c0a802bcd6590a398bf
Autor:
Maria Mazzarini, Francesca Arciprete, Orietta Picconi, Mauro Valeri, Paola Verachi, Fabrizio Martelli, Anna Rita Migliaccio, Mario Falchi, Maria Zingariello
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionHematopoietic stem cells (HSC) reside in the bone marrow (BM) in specialized niches which provide support for their self-replication and differentiation into the blood cells. Recently, numerous studies using sophisticated molecular and mi
Externí odkaz:
https://doaj.org/article/f560d9a0c5b145f0938afa5584f89a76
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/b11eec297f07408a8b6eb1c6c600fb62
Autor:
Lilian Varricchio, Eliza B Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell, James J Bieker, Thalia Papayannopoulou, Anna Rita Migliaccio
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Although human cell cultures stimulated with dexamethasone suggest that the glucocorticoid receptor (GR) activates stress erythropoiesis, the effects of GR activation on erythropoiesis in vivo remain poorly understood. We characterized the phenotype
Externí odkaz:
https://doaj.org/article/f80a9890609448fab4cd27aeee61f49c
Autor:
Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Andrea Martinelli, Giuseppe Sarli, Andrew Dunbar, Ross L. Levine, Ronald Hoffman, Maria Teresa Massucci, Laura Brandolini, Cristina Giorgio, Marcello Allegretti, Anna Rita Migliaccio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A major role for human (h)CXCL8 (interleukin-8) in the pathobiology of myelofibrosis (MF) has been suggested by observations indicating that MF megakaryocytes express increased levels of hCXCL8 and that plasma levels of this cytokine in MF patients a
Externí odkaz:
https://doaj.org/article/0db29a2696ee40889d806192b1234978
Autor:
Fabrizio Martelli, Paola Verachi, Maria Zingariello, Maria Mazzarini, Alessandro M. Vannucchi, Annalisa Lonetti, Barbara Bacci, Giuseppe Sarli, Anna Rita Migliaccio
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The phenotype of mice carrying the Gata1low mutation that decreases expression of Gata1 in erythroid cells and megakaryocytes, includes anemia, thrombocytopenia, hematopoietic failure in bone marrow and development of extramedullary hematopoiesis in
Externí odkaz:
https://doaj.org/article/83bb7b53c94a4cefafe67836d54efabc
Autor:
Annalisa Lonetti, Valentina Indio, Irma Dianzani, Ugo Ramenghi, Lydie Da Costa, Dagmar Pospíšilová, Anna Rita Migliaccio
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
NR3C1, the gene encoding the glucocorticoid receptor, is polymorphic presenting numerous single nucleotide polymorphisms (SNPs) some of which are emerging as leading cause in the variability of manifestation and/or response to glucocorticoids in huma
Externí odkaz:
https://doaj.org/article/1462818fb870486fb96eee9b1dedf86e
Autor:
Lilian Varricchio, Camelia Iancu-Rubin, Bhaskar Upadhyaya, Maria Zingariello, Fabrizio Martelli, Paola Verachi, Cara Clementelli, Jean-Francois Denis, Adeeb H. Rahman, Gilles Tremblay, John Mascarenhas, Ruben A. Mesa, Maureen O’Connor-McCourt, Anna Rita Migliaccio, Ronald Hoffman
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Myelofibrosis (MF) is a progressive chronic myeloproliferative neoplasm characterized by hyperactivation of JAK/STAT signaling and dysregulation of the transcription factor GATA1 in megakaryocytes (MKs). TGF-β plays a pivotal role in the pathobiolog
Externí odkaz:
https://doaj.org/article/aa050974d8234556ab4fc5e42238e3c0
Autor:
Francesca Arciprete, Paola Verachi, Fabrizio Martelli, Mauro Valeri, Manjola Balliu, Paola Guglielmelli, Alessandro Maria Vannucchi, Anna Rita Migliaccio, Maria Zingariello
Publikováno v:
Experimental Hematology. 121:30-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7976d4bb9520232eaa2625f115eca54
https://doi.org/10.1016/j.exphem.2023.02.003
https://doi.org/10.1016/j.exphem.2023.02.003