Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Anna Richter"'
Publikováno v:
IEEE Access, Vol 12, Pp 148167-148189 (2024)
Multivariate time series (MTS) are captured in a great variety of real-world applications. However, analysing and modeling the data for classification and forecasting purposes can become very challenging if values are missing in the data set. The nee
Externí odkaz:
https://doaj.org/article/d8121295f7d44b12ba38ceec205b7ff0
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Plants, animals and humans metabolically produce volatile isoprene (C5H8). Humans continuously exhale isoprene and exhaled concentrations differ under various physio-metabolic and pathophysiological conditions. Yet unknown metabolic origin h
Externí odkaz:
https://doaj.org/article/3e8b648286884c2d9cf389ff1f16582c
Autor:
Anna Richter
Publikováno v:
Quaestio Facti, Iss 5 (2023)
En los últimos años, la figura del arrepentido ha recibido un mayor interés, que también se refleja en su inclusión –de manera explícita o implícita– en diferentes ordenamientos jurídicos. Junto con ello aumentaron las discusiones alreded
Externí odkaz:
https://doaj.org/article/9df16c86461e4f70971dfc29ac49139c
Autor:
Anna Richter, Sandra Lange, Clemens Holz, Luisa Brock, Thomas Freitag, Anett Sekora, Gudrun Knuebel, Saskia Krohn, Rico Schwarz, Burkhard Hinz, Hugo Murua Escobar, Christian Junghanss
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Dysregulation of the intrinsic BCL-2 pathway-mediated apoptosis cascade is a common feature of hematological malignancies including acute B-lymphoblastic leukemia (B-ALL). The KMT2A-rearranged high-risk cytogenetic subtype is characterized b
Externí odkaz:
https://doaj.org/article/f965715f9603445aaf305e682578afd1
Autor:
Anna Richter, Sina Sender, Annemarie Lenz, Rico Schwarz, Burkhard Hinz, Gudrun Knuebel, Anett Sekora, Hugo Murua Escobar, Christian Junghanss, Catrin Roolf
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Casein kinase II (CK2) is involved in multiple tumor-relevant signaling pathways affecting proliferation and apoptosis. CK2 is frequently upregulated in acute B-lymphoblastic leukemia (B-ALL) and can be targeted by the ATP-competi
Externí odkaz:
https://doaj.org/article/bf338d2f4e8c4aaaafa01b0ae93d5af2
Autor:
Clemens Holz, Sandra Lange, Anett Sekora, Gudrun Knuebel, Saskia Krohn, Hugo Murua Escobar, Christian Junghanss, Anna Richter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1359 (2023)
Numerous hematologic neoplasms, including acute B-lymphoblastic leukemia (B-ALL), are characterized by overexpression of anti-apoptotic BCL-2 family proteins. Despite the high clinical efficacy of the specific BCL-2 inhibitor venetoclax in acute myel
Externí odkaz:
https://doaj.org/article/f7717778f5544ab8a8bbb6b1b39740c6
Autor:
Anna Richter, Catrin Roolf, Mohamed Hamed, Yvonne Saara Gladbach, Sina Sender, Christoph Konkolefski, Gudrun Knübel, Anett Sekora, Georg Fuellen, Brigitte Vollmar, Hugo Murua Escobar, Christian Junghanss
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The tumor suppressor protein phosphatase and tensin homolog (PTEN) is a key regulator of the PI3K/AKT pathway which is frequently altered in a variety of tumors including a subset of acute B-lymphoblastic leukemias (B-ALL). While
Externí odkaz:
https://doaj.org/article/4ab4ae59d44f423587e5d283cffbd82d
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e05922- (2021)
Background: Isoprene (C5H8) is a clinically important breath metabolite. Although, hundreds of studies have reported differential expressions in isoprene exhalation as breath biomarker for diverse diseases, the substance couldn't enter to clinical pr
Externí odkaz:
https://doaj.org/article/c575032bff9c49398e20fe9f6ebf58c9
Autor:
Anna Richter
Publikováno v:
Argumentos, Vol 2020, Iss 10 (2020)
En la primera mitad del 2019, la editorial Ad-Hoc publicó un libro pequeño pero contundente con el título Régimen penal y procesal del arrepentido y la delación premiada. Incorporación de la Ley 27304 al Código Procesal Penal Federal —Ley 27
Externí odkaz:
https://doaj.org/article/2b649249846845899b7da1873207e43c
Autor:
Rico Schwarz, Anna Richter, Elisabeth R. D. Ito, Hugo Murua Escobar, Christian Junghanß, Burkhard Hinz
Publikováno v:
Molecules, Vol 27, Iss 8, p 2394 (2022)
Silmitasertib (CX-4945) is currently being investigated in clinical trials against various types of cancer. The U.S. Food and Drug Administration (FDA) has already granted orphan drug designation to the compound for the treatment of advanced cholangi
Externí odkaz:
https://doaj.org/article/2658349d150549cabff5a7c8d6a1381f