Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anna R. Reynolds"'
Autor:
Sean D. Regnier, William W. Stoops, Joshua A. Lile, Joseph L. Alcorn, B. Levi Bolin, Anna R. Reynolds, Lon R. Hays, Abner O. Rayapati, Craig R. Rush
Publikováno v:
Pharmacology Biochemistry and Behavior. 224:173526
Publikováno v:
Experimental and Clinical Psychopharmacology. 24:185-192
Preclinical research has indicated that females may be more sensitive to the rewarding properties of cocaine. However, the majority of this research has been done in rodent species. Environmental cues associated with human drug-taking behavior tend t
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:1454-1461
Background Prior studies demonstrate that ethanol (EtOH) exposure induces the release of intracellular calcium (CA2+) in modulation of γ-aminobutyric acid-ergic tone and produces concomitant alterations in sigma (σ)-1 protein expression that may co
Autor:
Sarah E. Maggio, C.E. Van Skike, Anna R. Reynolds, Linda P. Dwoskin, Kimberly Nixon, Michael T. Bardo, E.M. Casey, Mark A. Prendergast
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 65:269-287
Polysubstance abuse of alcohol and nicotine has been overlooked in our understanding of the neurobiology of addiction and especially in the development of novel therapeutics for its treatment. Estimates show that as many as 92% of people with alcohol
Publikováno v:
Drug and Alcohol Dependence. 156:213-220
Background Group 1 mGlu-family proteins (i.e., mGlu) consist of mGlu1 and mGlu5 and their activity may influence voluntary ethanol intake. The present studies sought to examine the influence of these receptors on the development of ethanol dependence
Autor:
Ibrahim S. Elgumati, Honoree’ W. Brewton, Anna R. Reynolds, Mark A. Prendergast, Sydney R. Winchester, Meredith A. Saunders
Publikováno v:
Drug and Alcohol Dependence. 154:100-104
Background The development of ethanol dependence is associated with alterations in hypothalamic–pituitary–adrenal (HPA) axis and activation of type II glucocorticoid receptors (GR). These effects may contribute to withdrawal-associated anxiety, c
Publikováno v:
Alcohol (Fayetteville, N.Y.)
Chronic intermittent ethanol consumption is associated with neurodegeneration and cognitive deficits in preclinical laboratory animals and in the clinical population. While previous work suggests a role for neuroadaptations in the N-methyl-d-aspartat
Background Medications development efforts for methamphetamine-use disorder have targeted central monoamines because these systems are directly involved in the effects of methamphetamine. Buspirone is a dopamine autoreceptor and D3 receptor antagonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80026183037e99702f7324799d1888b0
https://europepmc.org/articles/PMC5683915/
https://europepmc.org/articles/PMC5683915/
Autor:
Anna R. Reynolds, Lynda J. Sharrett-Field, Jennifer N. Berry, Sydney R. Winchester, Mark A. Prendergast, Meredith A. Saunders
Chronic, intermittent ethanol (CIE) exposure is known to produce neuroadaptive alterations in excitatory neurotransmission that contribute to the development of dependence. Although activation of protein kinases (e.g., cyclic AMP [cAMP]-dependent pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac2ad93e301531a88f85299771d027b
https://europepmc.org/articles/PMC6662204/
https://europepmc.org/articles/PMC6662204/
Autor:
Lynda J. Sharrett-Field, Tracy Butler, Jennifer N. Berry, Anna R. Reynolds, Mark A. Prendergast
Publikováno v:
Alcoholism: Clinical and Experimental Research. 37:1417-1423
Stress Often Precedes the development of alcohol dependence and is also a consequence of dependence, thereby perpetuating the cycle of dependence, withdrawal, and relapse to alcohol use (Heilig et al., 2010; Koob and Kreek, 2007). Indeed, many indivi