Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anna R Patten"'
Publikováno v:
Frontiers in Pediatrics, Vol 2 (2014)
Prenatal ethanol exposure (PNEE) has been linked to widespread impairments in brain structure and function. There are a number of animal models that are used to study the structural and functional deficits caused by prenatal ethanol exposure, includi
Externí odkaz:
https://doaj.org/article/104261162888416491368aa2420d0fda
Publikováno v:
Frontiers in Neuroscience, Vol 4 (2010)
Some toxins and drugs can trigger lasting neuroprotective mechanisms that enable neurons to resist a subsequent severe insult. This ‘pharmacological preconditioning’ has far-reaching implications for conditions in which blood flow to the brain is
Externí odkaz:
https://doaj.org/article/4fae3483bdbb4ef5bf7548b46f03851a
Autor:
Luis E.B. Bettio, Emma Katherine Woo, Michal P. Jurkowski, Suk Yu Yau, Anna R. Patten, Joana Gil-Mohapel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Convincing evidence has repeatedly shown that new neurons are produced in the mammalian brain into adulthood. Adult neurogenesis has been best described in the hippocampus and the subventricular zone (SVZ), in which a series of distinct stages of neu
Publikováno v:
Frontiers in Neuroendocrinology. 41:23-43
The hippocampus plays an integral role in certain aspects of cognition. Hippocampal structural plasticity and in particular adult hippocampal neurogenesis can be influenced by several intrinsic and extrinsic factors. Here we review how hormones (i.e.
Autor:
Francis L. Pazini, Luis E.B. Bettio, Ana Lúcia S. Rodrigues, Patricia S. Brocardo, Brian R. Christie, Joana Gil-Mohapel, Vivian B. Neis, Anna R. Patten
Publikováno v:
European Journal of Neuroscience. 43:1006-1015
Guanosine is a purine nucleoside that occurs naturally in the central nervous system, exerting trophic effects. Given its neuroprotective properties, the potential of guanosine as an antidepressant has been recently examined. Within this context, the
Autor:
Alicia Meconi, Anna R. Patten, Brian R. Christie, Suk Yu Yau, Christine J. Fontaine, Ryan C. Wortman
Publikováno v:
Brain Plasticity
In this review, the benefits of physical exercise on structural and functional plasticity in the hippocampus are discussed. The evidence is clear that voluntary exercise in rats and mice can lead to increases in hippocampal neurogenesis and enhanced
Autor:
Andrea K. Titterness, Andrea Ratzlaff, S. Taylor, Jennifer L. Helfer, T. Ratzlaff, Anna R. Patten, Brian R. Christie, Joana Gil-Mohapel
Publikováno v:
Neuroscience. 273:174-188
Exposure to ethanol in utero is associated with a myriad of sequelae for the offspring. Some of these effects are morphological in nature and noticeable from birth, while others involve more subtle changes to the brain that only become apparent later
Autor:
C. Zhang, R. Parton, Kristin Morch, L. Szlavik, S. Sawchuk, H.M. Sickmann, Anna R. Patten, Brian R. Christie
Publikováno v:
Hippocampus. 24:54-64
Alcohol consumption during pregnancy is deleterious to the developing brain of the fetus and leads to persistent deficits in adulthood. Long-term potentiation (LTP) is a biological model for learn- ing and memory processes and previous evidence has s
Autor:
Ryan C. Wortman, Athena Noonan, Claire Sakiyama, Joana Gil-Mohapel, Brian R. Christie, Patricia S. Brocardo, Anna R. Patten
Publikováno v:
Hippocampus. 23:1463-1475
Previous studies from our laboratory have shown that prenatal ethanol exposure (PNEE) causes a significant deficit in synaptic plasticity, namely long-term potentiation (LTP), in the dentate gyrus (DG) region of the hippocampus of male rats. PNEE has
Publikováno v:
Neuroscience Letters. 551:7-11
Fetal alcohol spectrum disorders result in long-lasting neurological deficits including decreases in synaptic plasticity and deficits in learning and memory. In this study we examined the effects of prenatal ethanol exposure on hippocampal synaptic p