Zobrazeno 1 - 2
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pro vyhledávání: '"Anna Rönnborg"'
Autor:
Annika Åstrand, Anna Rönnborg, Emma Lindhardt, Ulrik Gran, Gert Strandlund, Hans Emtenäs, Zhong-Qing Yuan, Jonas Boström, Johan Sundell, Jonna Gyll, Ågot Högberg, Boel Löfberg, Tommy Iliefski, Roine I. Olsson, Birgit Andersson, Olle Hidestål, Tor Svensson, Ingemar Jacobson, Elin Forsström, Frida Persson, Christina Olsson, Annika Björe, Gunilla Linhardt, Öjvind Davidsson, Ola Fjellström, Jesper Malmberg
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(5)
A series of lactam sulfonamides has been discovered and optimized as inhibitors of the Kv1.5 potassium ion channel for treatment of atrial fibrillation. In vitro structure–activity relationships from lead structure C to optimized structure 3y are d
Publikováno v:
Blood. 112:5459-5459
AR-H067637 is a direct thrombin inhibitor derived in vivo from the orally available prodrug AZD0837. AZD0837 is in development for use in thromboembolic disorders. This study investigated the additional effects of aspirin (ASA) alone and in combinati