Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Anna R, Docherty"'
Autor:
Allison E Ashley-Koch, Nathan A Kimbrel, Xue J Qin, Jennifer H Lindquist, Melanie E Garrett, Michelle F Dennis, Lauren P Hair, Jennifer E Huffman, Daniel A Jacobson, Ravi K Madduri, Hilary Coon, Anna R Docherty, Jooeun Kang, Niamh Mullins, Douglas M Ruderfer, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, International Suicide Genetics Consortium, Philip D Harvey, Benjamin H McMahon, David W Oslin, Elizabeth R Hauser, Michael A Hauser, Jean C Beckham
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010623 (2023)
Suicidal ideation (SI) often precedes and predicts suicide attempt and death, is the most common suicidal phenotype and is over-represented in veterans. The genetic architecture of SI in the absence of suicide attempt (SA) is unknown, yet believed to
Externí odkaz:
https://doaj.org/article/4d6850e6746b413a90e0435fdd0699ad
Autor:
Monika A. Waszczuk, Olga Morozova, Elizabeth Lhuillier, Anna R. Docherty, Andrey A. Shabalin, Xiaohua Yang, Melissa A. Carr, Sean A. P. Clouston, Roman Kotov, Benjamin J. Luft
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Background Genetic factors contribute to individual differences in the severity of coronavirus disease 2019 (COVID-19). A portion of genetic predisposition can be captured using polygenic risk scores (PRS). Relatively little is known about the associ
Externí odkaz:
https://doaj.org/article/b4c2779ce0b84324bfe5c2e52357514c
Autor:
Eric T. Monson, Andrey A. Shabalin, Anna R. Docherty, Emily DiBlasi, Amanda V. Bakian, Qingqin S. Li, Douglas Gray, Brooks Keeshin, Sheila E. Crowell, Niamh Mullins, Virginia L. Willour, Hilary Coon
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Bipolar disorder (BP) suicide death rates are 10–30 times greater than the general population, likely arising from environmental and genetic risk factors. Though suicidal behavior in BP has been investigated, studies have not addressed com
Externí odkaz:
https://doaj.org/article/eaefc5bd42cf41b9a7782f258e8aff16
Autor:
Frank D. Mann, Sean A.P. Clouston, Adolfo Cuevas, Monika A. Waszczuk, Pei-Fen Kuan, Melissa A. Carr, Anna R. Docherty, Andrea A. Shabalin, Sam E. Gandy, Benjamin J. Luft
Publikováno v:
Journal of Alzheimer's Disease. 92:701-712
Background: There is a high incidence of cognitive impairment among World Trade Center (WTC) responders, comorbid with post-traumatic stress disorder (PTSD). Yet, it remains unknown whether genetic liability for Alzheimer’s disease, PTSD, education
Autor:
Tiffany Love, Andrey A. Shabalin, Rachel L. Kember, Anna R. Docherty, Hang Zhou, Vincent Koppelmans, Joel Gelernter, Anne K. Baker, Emily Hartwell, Jacob Dubroff, Jon-Kar Zubieta, Henry R. Kranzler
Publikováno v:
Neuropsychopharmacology. 47:1784-1790
Publikováno v:
Schizophr Res
Autor:
Hilary Coon, Andrey Shabalin, Amanda V. Bakian, Emily DiBlasi, Eric T. Monson, Anne Kirby, Danli Chen, Alison Fraser, Zhe Yu, Michael Staley, William Brandon Callor, Erik D. Christensen, Sheila E. Crowell, Douglas Gray, David K. Crockett, Qingqin S. Li, Brooks Keeshin, Anna R. Docherty
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 189:60-73
Suicide accounts for800,000 deaths annually worldwide; prevention is an urgent public health issue. Identification of risk factors remains challenging due to complexity and heterogeneity. The study of suicide deaths with increased extended familial r
Autor:
Anna R. Docherty, Vimla Aggarwal, James M. McNamara, Ayan Malakar, Daniel Hughes, Andrey A. Shabalin, Anat Grossman-Jonish, Lior Greenbaum, Gundula Povysil, Shannon Delaney, Hann-Shyan Hwang, Evan H. Baugh, David Goldstein, Anna Alkelai, Emma P. Peabody, Matthew B. Harms, Sahar Gelfman, Bernard Lerer, Vaidehi Jobanputra, Ann E. Pulver, Anthony W. Zoghbi, Erin L. Heinzen
Publikováno v:
Molecular Psychiatry. 27:1435-1447
Schizophrenia has a multifactorial etiology, involving a polygenic architecture. The potential benefit of whole genome sequencing (WGS) in schizophrenia and other psychotic disorders is not well studied. We investigated the yield of clinical WGS anal
Autor:
Andrey A. Shabalin, Emily DiBlasi, Erik Christensen, Eric T. Monson, Douglas Gray, Amanda V. Bakian, Danli Chen, Hilary Coon, Brooks R. Keeshin, Anna R. Docherty, Qingqin Li
Publikováno v:
Schizophr Bull
Approximately 5% of individuals with schizophrenia die from suicide. However, suicide in psychosis is still poorly characterized, partly due to a lack of adequate population-based clinical or genetic data on suicide death. The Utah Suicide Genetics R
Autor:
Heidi A. Hanson, Chong Zhang, Yue Zhang, Ken R. Smith, Danli Chen, Amanda V. Bakian, James VanDerslice, Anna R. Docherty, Douglas Gray, David Z. Yu, Brooks R. Keeshin, Hilary Coon
Publikováno v:
Psychological Medicine. 53:1448-1457
BackgroundThe degree to which suicide risk aggregates in US families is unknown. The authors aimed to determine the familial risk of suicide in Utah, and tested whether familial risk varies based on the characteristics of the suicides and their relat