Short-term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis

Autor: Anna Prossomariti, Eleonora Scaioli, Giulia Piazzi, Chiara Fazio, Matteo Bellanova, Elena Biagi, Marco Candela, Patrizia Brigidi, Clarissa Consolandi, Tiziana Balbi, Pasquale Chieco, Alessandra Munarini, Milena Pariali, Manuela Minguzzi, Franco Bazzoli, Andrea Belluzzi, Luigi Ricciardiello

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)

Abstract Patients with long-standing ulcerative colitis (UC) have an increased colorectal cancer (CRC) risk. In this pilot study we evaluated the effect of Eicosapentaenoic acid as free fatty acid (EPA-FFA) supplementation on mucosal disease activity

Externí odkaz: https://doaj.org/article/4e3561bd67f740f69cdf357ffa89ab3f

Nucleotide-Binding Domain Leucine-Rich Repeat Containing Proteins and Intestinal Microbiota: Pivotal Players in Colitis and Colitis-Associated Cancer Development

Autor: Anna Prossomariti, Harry Sokol, Luigi Ricciardiello

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

The nucleotide-binding domain leucine-rich repeat containing (NLR) proteins play a fundamental role in innate immunity and intestinal tissue repair. A dysbiotic intestinal microbiota, developed as a consequence of alterations in NLR proteins, has rec

Externí odkaz: https://doaj.org/article/b40c2fe96cb64752866377883c586cb8

Supplementary Materials and Methods from miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4

Autor: Luigi Ricciardiello, Franco Bazzoli, Claudio Montagna, Chiara Alquati, Daniela Turchetti, Sara Miccoli, Leonarda D'Angelo, Giulia Piazzi, Anna Prossomariti

APC gene target sequencing and in silico analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f6bff73b50af8042127adb685cd56
https://doi.org/10.1158/1541-7786.22512121

Are Wnt/β-Catenin and PI3K/AKT/mTORC1 Distinct Pathways in Colorectal Cancer?Summary

Autor: Luigi Ricciardiello, Giulia Piazzi, Chiara Alquati, Anna Prossomariti

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology

Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in colorectal cancer (CRC) development, although they are implicated in the modulation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7a306ac692719a8347e0c547725351
http://www.sciencedirect.com/science/article/pii/S2352345X20300515

Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact

Autor: Giulia Piazzi, Francesco Buttitta, Luigi Laghi, Franco Bazzoli, Luigi Ricciardiello, Anna Prossomariti, Chiara Alquati

Publikováno v: Cancers, Vol 13, Iss 2081, p 2081 (2021)
Cancers

Simple Summary Colorectal cancer (CRC) is one of the most common malignancies worldwide. Next-generation sequencing technologies have identified new candidate genes and deepened the knowledge of the molecular mechanisms underlying the progression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4765461951668bd08594ee06c155b99
https://doi.org/10.3390/cancers13092081