Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anna Polosa"'
Autor:
Catherine Argyriou, Anna Polosa, Ji Yun Song, Samy Omri, Bradford Steele, Bruno Cécyre, Devin S. McDougald, Erminia Di Pietro, Jean-François Bouchard, Jean Bennett, Joseph G. Hacia, Pierre Lachapelle, Nancy E. Braverman
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 225-240 (2021)
Patients with Zellweger spectrum disorder (ZSD) commonly present with vision loss due to mutations in PEX genes required for peroxisome assembly and function. Here, we evaluate PEX1 retinal gene augmentation therapy in a mouse model of mild ZSD beari
Externí odkaz:
https://doaj.org/article/8cbf07d636cf46afa1661d18efa2eb4c
Autor:
Mercedes Gauthier, Antoine Brassard Simard, Anna Polosa, Allison L. Dorfman, Cynthia X. Qian, Jean-Marc Lina, Pierre Lachapelle
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The electroretinogram (ERG) represents the biopotential evoked by the retina in response to a light stimulus. The flash evoked ERG (fERG) is the ERG modality most frequently used clinically to diagnose and monitor retinal disorders. We hereby present
Externí odkaz:
https://doaj.org/article/c18f1720e1b6414a996470cb5cc85d53
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158082 (2016)
The purpose of this study was to better understand the role of ocular pigmentation and genetics in light-induced retinal damage. Adult pigmented [Long Evans (LE) and Brown Norway (BN)] and albino [Sprague Dawley (SD) and Lewis (LW)] rats were exposed
Externí odkaz:
https://doaj.org/article/ca2e6c0e64724610a4df72dc4f120d55
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146979 (2016)
In the present study, we aimed at better understanding the short (acute) and long term (chronic) degenerative processes characterizing the juvenile rat model of light-induced retinopathy. Electroretinograms, visual evoked potentials (VEP), retinal hi
Externí odkaz:
https://doaj.org/article/fe04237e5a4841119de91564e63da544
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136056 (2015)
Biological sex and age are considered as two important factors that may influence the function and structure of the retina, an effect that might be governed by sexual hormones such as estrogen. The purpose of this study was to delineate the influence
Externí odkaz:
https://doaj.org/article/77bfc52f1a6948be9279bb53e85da59a
Autor:
Jean-François Bouchard, Pierre Lachapelle, Samy Omri, Nancy Braverman, Devin S. McDougald, Ji Yun Song, Erminia Di Pietro, Bruno Cécyre, Catherine Argyriou, Anna Polosa, Joseph G. Hacia, Jean Bennett, Bradford H. Steele
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 225-240 (2021)
Patients with Zellweger spectrum disorder (ZSD) commonly present with vision loss due to mutations in PEX genes required for peroxisome assembly and function. Here, we evaluate PEX1 retinal gene augmentation therapy in a mouse model of mild ZSD beari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27287904ece42349e0b1e5e750c3b06d
https://doi.org/10.1016/j.omtm.2021.09.002
https://doi.org/10.1016/j.omtm.2021.09.002
Autor:
Catherine, Argyriou, Anna, Polosa, Ji Yun, Song, Samy, Omri, Bradford, Steele, Bruno, Cécyre, Devin S, McDougald, Erminia, Di Pietro, Jean-François, Bouchard, Jean, Bennett, Joseph G, Hacia, Pierre, Lachapelle, Nancy E, Braverman
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Patients with Zellweger spectrum disorder (ZSD) commonly present with vision loss due to mutations in PEX genes required for peroxisome assembly and function. Here, we evaluate PEX1 retinal gene augmentation therapy in a mouse model of mild ZSD beari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f8aa50923c0af1a5b2428d165b56020
https://pubmed.ncbi.nlm.nih.gov/34703844
https://pubmed.ncbi.nlm.nih.gov/34703844
Publikováno v:
Current Eye Research. 42:924-935
The purpose of this study was to compare the efficacy that ocular melanin confers in protecting the retina of juvenile and adult rats exposed to a bright luminous environment.Juvenile (JLE) and adult (ALE) Long-Evans pigmented rats were thus exposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92738aa3decca24efde1e15d668d4bb
https://doi.org/10.1080/02713683.2016.1255336
https://doi.org/10.1080/02713683.2016.1255336
Autor:
Zhuo Shao, Pierre Lachapelle, Tang Zhu, Anna Polosa, Santiago Costantino, Gregory A. Lodygensky, Houda Tahiri, José Carlos Rivera, Allison Dorfman, Tianwei E. Zhou, Sylvain Chemtob, Vikrant K. Bhosle, Alexandra Beaudry-Richard, Isabelle Lahaie
Publikováno v:
The American Journal of Pathology. 186:3100-3116
Retinopathy of prematurity (ROP), the most common cause of blindness in premature infants, has long been associated with inner retinal alterations. However, recent studies reveal outer retinal dysfunctions in patients formerly afflicted with ROP. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9962c4c77f80fbc3e2593691f295ef92
https://doi.org/10.1016/j.ajpath.2016.08.004
https://doi.org/10.1016/j.ajpath.2016.08.004
Autor:
Rached Azaiz, Soumaya Amara, Pierre Lachapelle, Imane Hammoum, Rafika Ben Chaouacha-Chekir, Mohamed Dogui, Sihem Mbarek, Riadh Messaoud, Ahmed Dellaa, Anna Polosa, Ridha Charfeddine, Moncef Khairallah
Publikováno v:
Current Eye Research. 42:79-87
To compare the retinal function of a diurnal murid rodent, Psammomys obesus, with that of Wistar albino rat and human subjects.Adult Psammomys obesus were captured and transferred to the animal facilities where they were maintained at 25°C with stan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198768207114f56f1a9d420319ce3766
https://doi.org/10.3109/02713683.2016.1141963
https://doi.org/10.3109/02713683.2016.1141963