Výsledky vyhledávání

Comparable TNF-alpha, IFN-gamma and GM-CSF production by purified normal marrow CD3 cells in response to horse anti-lymphocyte and rabbit antithymocyte globulin

Autor: F. Benvenuto, B. Bruno, G. B. Pittaluga, A. Isaza, Anna Pitto, M Podesta, Almalina Bacigalupo, Giovanna Piaggio

Publikováno v: European Journal of Haematology. 60:240-244

In vitro priming of T cell with horse antilymphocyte globulin (HALG) results in cytokine release, and this has been associated with its clinical efficacy in patients with severe aplastic anaemia (SAA). Rabbit antithymocyte globulin (RATG) has been st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775d9353802cf34a1db5417f03f6b927
https://doi.org/10.1111/j.1600-0609.1998.tb01030.x

Zobrazit plný text záznamu

Progenitor cells trapped in marrow filters can reduce GvHD and transplant mortality

Autor: M Podesta, Silvia Lucchetti, Elisabetta Tedone, Adalberto Ibatici, M. T. Van Lint, Anna Pitto, Nicoletta Sacchi, Francesco Frassoni, Giovanna Piaggio, Teresa Lamparelli, Simonetta Pozzi, Almalina Bacigalupo, Dany Vicente, O. Figari

Publikováno v: Bone Marrow Transplantation. 38:111-117

A bone marrow harvest is filtered either in the operating room, in the laboratory or during infusion to the patient. Filters are usually discarded. Little is known of haemopoietic progenitor cells (HPCs) trapped in the filters. The aim of the study w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2035744082bb242f3ffbcb48d15287e5
https://doi.org/10.1038/sj.bmt.1705413

Zobrazit plný text záznamu

Intra–bone marrow injection of bone marrow and cord blood cells: an alternative way of transplantation associated with a higher seeding efficiency

Autor: Andrea Bacigalupo, Daniele Scarpati, Adalberto Ibatici, Lorenzo Magrassi, Marina Podestà, Sandra Castello, Anna Pitto, Francesco Frassoni, Vincenzo G. Menditto, Giovanna Piaggio, O. Figari

Publikováno v: Experimental Hematology. 32:782-787

Objective Intravenous (IV) injection is currently the normal method for transplanting hematopoietic cells. However, the problem of seeding efficiency and homing is relevant especially when a limited number of stem cells is available. Intra–bone mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c3d1a7868b6e373fddab11109932b3
https://doi.org/10.1016/j.exphem.2004.05.026

Zobrazit plný text záznamu

Reduced intensity thiotepa-cyclophosphamide conditioning for allogeneic haemopoietic stem cell transplants (HSCT) in patients up to 60 years of age

Autor: Anna Maria Raiola, Nicola Mordini, Stefania Bregante, Francesco Frassoni, G. Berisso, M. T. Van Lint, F. Di Stefano, Anna Pitto, Teresa Lamparelli, Almalina Bacigalupo, G Fugazza, Mario Sessarego, Francesca Gualandi

Publikováno v: British Journal of Haematology. 109:716-721

Transplant-related mortality (TRM) remains a major problem in older patients undergoing allogeneic haemopoietic stem cell transplants (HSCTs). We have therefore explored a less intensive conditioning in 33 patients with a median age of 52 years (rang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7d6aad94b0f0afd874972171c3d4550
https://doi.org/10.1046/j.1365-2141.2000.02123.x

Zobrazit plný text záznamu

Autografting with Ph-negative progenitors in patients at diagnosis of chronic myeloid leukemia induces a prolonged prevalence of Ph-negative hemopoiesis

Autor: Francesco Frassoni, Giuseppina Fugazza, M. Soracco, Angelo Michele Carella, Mario Cazzola, Anna Pitto, Vittorio Rosti, Andrea Bacigalupo, Mario Sessarego, Giovanbattista Ravera, A. Dejana, Marina Podestà, Giovanna Piaggio, O. Figari, Enrica Lerma

Publikováno v: Experimental Hematology. 28:210-215

Objective In many patients with chronic myeloid leukemia (CML), a residual population of primitive normal (Ph-negative) progenitors persists despite the marked expansion of the leukemic (Ph-positive) clone. These cells may be found in the blood of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7195ca3cd7efb96e94b19b925ec621
https://doi.org/10.1016/s0301-472x(99)00147-2

Zobrazit plný text záznamu

Phenotypic and functional analysis of the HLA-class I-specific inhibitory receptors of natural killer cells isolated from peripheral blood of patients undergoing bone marrow transplantation from matched unrelated donors

Autor: Marco Ponte, Federica Benvenuto, Lorenzo Moretta, Anna Pitto, Andrea Bacigalupo, Chiara Vitale, Maria Cristina Mingari, Rosa Bellomo, Francesco Frassoni

Publikováno v: The Hematology Journal. 1:136-144

INTRODUCTION Limited information is available on the natural killer cell reconstitution after bone marrow transplantation and on the possible role of these cells in graft-versus-host-disease. MATERIALS AND METHODS Blood samples were collected at diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9363411cdd7b7fcee15a07d667bb64
https://doi.org/10.1038/sj.thj.6200018

Zobrazit plný text záznamu

Coexistence of normal and clonal haemopoiesis in aplastic anaemia patients treated with immunosuppressive therapy

Autor: Bénédicte Bruno, Francesco Frassoni, Giovanna Piaggio, Anna Pitto, Federica Benvenuto, Mario Sessarego, Mauro Truini, O. Figari, M. T. Van Lint, Marina Podestà, G Fugazza, Almalina Bacigalupo

Publikováno v: British Journal of Haematology. 107:505-511

Cytogenetic abnormalities and paroxysmal nocturnal haemoglobinuria (PNH) phenotype are frequent findings in aplastic anaemia patients treated with immunosuppressive therapy (IST). In this study we investigated whether the appearance of clonal haemopo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e04fc48fd62f178a3f198858b37a292
https://doi.org/10.1046/j.1365-2141.1999.01729.x

Zobrazit plný text záznamu

Normal primitive haemopoietic progenitors are more frequent than their leukaemic counterpart in newly diagnosed patients with chronic myeloid leukaemia but rapidly decline with time

Autor: O. Figari, Giovanna Piaggio, Vittorio Rosti, Mario Sessarego, Giuseppina Fugazza, Panagiotis Zikos, Francesco Frassoni, F Vassallo, Angelo Michele Carella, Federica Benvenuto, Anna Pitto, Marina Podestà, Mario Cazzola, Gaetano Bergamaschi

Publikováno v: British Journal of Haematology. 104:538-545

We carried out studies to quantify Ph-negative progenitors both in steady state and during regeneration after chemotherapy and G-CSF in 23 newly diagnosed chronic myeloid leukaemia (CML) patients (group A) and in 14 individuals more than a year from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54d581e1e03a4c1f1328dd062c3915fd
https://doi.org/10.1046/j.1365-2141.1999.01201.x

Zobrazit plný text záznamu

The Assessment of the Hematopoietic Reservoir After Immunosuppressive Therapy or Bone Marrow Transplantation in Severe Aplastic Anemia

Autor: Monica Abate, Francesco Frassoni, Giovanna Piaggio, Anna Pitto, Maria Teresa Van Lint, Andrea Bacigalupo, Panagiotis Zikos, G. Berisso, Mario Sessarego, Marina Podestà

Publikováno v: Scopus-Elsevier

We investigated the hematopoietic reservoir in 43 severe aplastic anemia (SAA) patients following immunosuppression (IS) (n = 15) or bone marrow transplantation (BMT) (n = 28), at a median interval of 5 years (range, 2-20) from treatment. All patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b9563e5582ceaca67a118c93c1d2a5
https://doi.org/10.1182/blood.v91.6.1959

Zobrazit plný text záznamu

Transplantation of HLA‐mismatched CD34 + selected cells in patients with advanced malignancies: severe immunodeficiency and related complications

Autor: Federica Benvenuto, Anna Pitto, G. Lercari, G. De Stefano, F Vassallo, Francesca Gualandi, Almalina Bacigalupo, M. Soracco, Domenico Occhini, Nicola Mordini, Stefania Bregante, Mauro Valbonesi, P. Carlier, M. T. Van Lint, Giovanna Piaggio, O. Figari, M Podesta, Teresa Lamparelli

Publikováno v: British Journal of Haematology. 98:760-766

This trial was designed to test the use of CD34 + selected haemopoietic stem cells (HSC) in HLA-mismatched donor-recipient pairs, following intensive conditioning with thiotepa, antilymphocyte globulin (ALG), cyclophosphamide and single-dose total-bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36734718d50992143bfa49d57b674af2
https://doi.org/10.1046/j.1365-2141.1997.2773094.x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání