Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anna Perdrix-Rosell"'
Autor:
Irene Rodriguez-Hernandez, Oscar Maiques, Leonie Kohlhammer, Gaia Cantelli, Anna Perdrix-Rosell, Joanne Monger, Bruce Fanshawe, Victoria L. Bridgeman, Sophia N. Karagiannis, Rosa M. Penin, Joaquim Marcolval, Rosa M. Marti, Xavier Matias-Guiu, Gilbert O. Fruhwirth, Jose L. Orgaz, Ilaria Malanchi, Victoria Sanz-Moreno
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Amoeboid cells are associated with melanoma invasive capacity. Here, the authors show that the WNT11-FZD7-DAAM1 pathway regulates tumour-initiating potential, invasion and metastasis lead by amoeboid cells in the invasive front of melanoma tumours.
Externí odkaz:
https://doaj.org/article/9e4929d31dc4466f83996eb59f8cabaf
Autor:
Probir Chakravarty, Anna Perdrix Rosell, Luigi Ombrato, Victoria Sanz-Moreno, Oscar Maiques, Ilaria Malanchi
Cancer cells thrive embedded in a fine-tuned cellular and extracellular environment or tumour microenvironment (TME). There is a general understanding of a co-evolution between cancer cells and their surrounding TME, pointing at a functional connecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743412dd0fa563c25e88ef8855da6509
https://doi.org/10.1101/2021.06.15.448466
https://doi.org/10.1101/2021.06.15.448466
Autor:
Joaquim Marcolval, Irene Rodriguez-Hernandez, Ilaria Malanchi, Gilbert O. Fruhwirth, Bruce Fanshawe, Leonie Kohlhammer, Rosa M. Martí, Oscar Maiques, R.M. Penín, Victoria L. Bridgeman, Joanne Monger, Xavier Matias-Guiu, Gaia Cantelli, Anna Perdrix-Rosell, Victoria Sanz-Moreno, Sophia N. Karagiannis, Jose L. Orgaz
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
Consejo Superior de Investigaciones Científicas (CSIC)
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Repositorio Abierto de la UdL
Universitad de Lleida
Rodriguez-Hernandez, I, Maiques, O, Kohlhammer, L, Cantelli, G, Perdrix-Rosell, A, Monger, J, Fanshawe, B, Bridgeman, V L, Karagiannis, S N, Penin, R M, Marcolval, J, Marti, R M, Matias-Guiu, X, Fruhwirth, G O, Orgaz, J L, Malanchi, I & Sanz-Moreno, V 2020, ' WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion ', Nature Communications, vol. 11, no. 1, 5315, pp. 5315 . https://doi.org/10.1038/s41467-020-18951-2
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Nature Communications
Consejo Superior de Investigaciones Científicas (CSIC)
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Repositorio Abierto de la UdL
Universitad de Lleida
Rodriguez-Hernandez, I, Maiques, O, Kohlhammer, L, Cantelli, G, Perdrix-Rosell, A, Monger, J, Fanshawe, B, Bridgeman, V L, Karagiannis, S N, Penin, R M, Marcolval, J, Marti, R M, Matias-Guiu, X, Fruhwirth, G O, Orgaz, J L, Malanchi, I & Sanz-Moreno, V 2020, ' WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion ', Nature Communications, vol. 11, no. 1, 5315, pp. 5315 . https://doi.org/10.1038/s41467-020-18951-2
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Nature Communications
Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasive strategies. We show here that high Myosin II activity, high levels of ki-67 and high tumour-initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30feb0aa6580ce44cc89db78d547e8ed
http://hdl.handle.net/10486/696040
http://hdl.handle.net/10486/696040
Autor:
Silvia Mele, Jo Monger, Sophia N. Karagiannis, Panagiotis Karagiannis, Mirella Georgouli, Lena Boehme, Oscar Maiques, Anna Perdrix-Rosell, Victoria L. Bridgeman, Amine Sadok, Victoria Sanz-Moreno, Rebecca Lee, Irene Rodriguez-Hernandez, Ilaria Malanchi, Fredrik Wallberg, Jose L. Orgaz, Pahini Pandya, Eva Crosas-Molist, Christopher J. Tape
Publikováno v:
Cancer Cell
Orgaz, J L, Crosas-Molist, E, Sadok, A, Perdrix-Rosell, A, Maiques, O, Rodriguez-Hernandez, I, Monger, J, Mele, S, Georgouli, M, Bridgeman, V, Karagiannis, P, Lee, R, Pandya, P, Boehme, L, Wallberg, F, Tape, C, Karagiannis, S N, Malanchi, I & Sanz-Moreno, V 2020, ' Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance ', Cancer Cell, vol. 37, no. 1, pp. 85-103.e9 . https://doi.org/10.1016/j.ccell.2019.12.003
CANCER CELL
Orgaz, J L, Crosas-Molist, E, Sadok, A, Perdrix-Rosell, A, Maiques, O, Rodriguez-Hernandez, I, Monger, J, Mele, S, Georgouli, M, Bridgeman, V, Karagiannis, P, Lee, R, Pandya, P, Boehme, L, Wallberg, F, Tape, C, Karagiannis, S N, Malanchi, I & Sanz-Moreno, V 2020, ' Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance ', CANCER CELL, vol. 37, no. 1, pp. 85-103.e9 . https://doi.org/10.1016/j.ccell.2019.12.003
Orgaz, J L, Crosas-Molist, E, Sadok, A, Perdrix-Rosell, A, Maiques, O, Rodriguez-Hernandez, I, Monger, J, Mele, S, Georgouli, M, Bridgeman, V, Karagiannis, P, Lee, R, Pandya, P, Boehme, L, Wallberg, F, Tape, C, Karagiannis, S N, Malanchi, I & Sanz-Moreno, V 2020, ' Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance ', Cancer Cell, vol. 37, no. 1, pp. 85-103.e9 . https://doi.org/10.1016/j.ccell.2019.12.003
CANCER CELL
Orgaz, J L, Crosas-Molist, E, Sadok, A, Perdrix-Rosell, A, Maiques, O, Rodriguez-Hernandez, I, Monger, J, Mele, S, Georgouli, M, Bridgeman, V, Karagiannis, P, Lee, R, Pandya, P, Boehme, L, Wallberg, F, Tape, C, Karagiannis, S N, Malanchi, I & Sanz-Moreno, V 2020, ' Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance ', CANCER CELL, vol. 37, no. 1, pp. 85-103.e9 . https://doi.org/10.1016/j.ccell.2019.12.003
Summary Despite substantial clinical benefit of targeted and immune checkpoint blockade-based therapies in melanoma, resistance inevitably develops. We show cytoskeletal remodeling and changes in expression and activity of ROCK-myosin II pathway duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80ff2407510ff4659e97caceb2b1d67
https://pubmed.ncbi.nlm.nih.gov/31935375
https://pubmed.ncbi.nlm.nih.gov/31935375
Publikováno v:
Current Biology
Olmos, Y, Perdrix Rosell, A & Carlton, J G 2016, ' Membrane binding by CHMP7 coordinates ESCRT-III dependent nuclear envelope reformation ', Current Biology, vol. 26, no. 19, pp. 2635-2641 . https://doi.org/10.1016/j.cub.2016.07.039
Olmos, Y, Perdrix Rosell, A & Carlton, J G 2016, ' Membrane binding by CHMP7 coordinates ESCRT-III dependent nuclear envelope reformation ', Current Biology, vol. 26, no. 19, pp. 2635-2641 . https://doi.org/10.1016/j.cub.2016.07.039
Summary In addition to its role in membrane abscission during cytokinesis, viral budding, endosomal sorting, and plasma membrane repair [1], the endosomal sorting complex required for transport-III (ESCRT-III) machinery has recently been shown to sea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2becb0144fc85905ae8d04af2bb09a72
https://doi.org/10.1101/049221
https://doi.org/10.1101/049221
Autor:
Steven Catchpole, Maggie C.U. Cheang, Gianmaria Liccardi, Jelmar Quist, Jonathan Watkins, Nirmesh Patel, Violeta Serra, Anita Grigoriadis, Erika Francesch Domenech, Fara Braso-Maristany, Andrew Tutt, Elodie Noel, Leila Zakka, Pierfrancesco Marra, Simone Filosto, Patrycja Gazinska, Rebecca Marlow, Anna Perdrix Rosell, Albert Gris
Publikováno v:
Cancer Research. 76:178-178
Triple-Negative Breast Cancers (TNBCs) are aggressive, associated with poor prognosis and lack targeted therapies, mainly due to the absence of suitable molecular targets. The genomic region 6p21-p25 is recurrently amplified in TNBCs and encompasses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d1842959ffc936f17b1bd0b4432aef
https://doi.org/10.1158/1538-7445.am2016-178
https://doi.org/10.1158/1538-7445.am2016-178
Autor:
Fara Brasó-Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist, Erika Francesch-Domenech, Darren A Plumb, Leila Zakka, Patrycja Gazinska, Gianmaria Liccardi, Pascal Meier, Albert Gris-Oliver, Maggie Chon U Cheang, Anna Perdrix-Rosell, Manar Shafat, Elodie Noël, Nirmesh Patel, Kristen McEachern, Maurizio Scaltriti, Pau Castel, Farzana Noor, Richard Buus, Sumi Mathew, Johnathan Watkins, Violeta Serra, Pierfrancesco Marra, Anita Grigoriadis, Andrew N Tutt
Publikováno v:
Nature Medicine. 23:788-788
Triple-negative breast cancers (TNBCs) have poor prognosis and lack targeted therapies. Interrogation of genomic datasets identified increased PIM1 copy number-driven expression in TNBC. RNA interference in breast cancer and non-malignant mammary epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e9e254631f5c47ac0d13d4513d16aa
https://doi.org/10.1038/nm0617-788b
https://doi.org/10.1038/nm0617-788b
Autor:
'Anna Perdrix Rosell
Publikováno v:
Oscar Maiques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::e849fd5727841fadc5f6e672da6f87bb
Autor:
Anna Perdrix Rosell, Oscar Maiques, Joshua Alexander James Martin, Probir Chakravarty, Luigi Ombrato, Victoria Sanz-Moreno, Ilaria Malanchi
Publikováno v:
Cancer Letters. 544:215800
Cancer cells thrive when embedded in a fine-tuned cellular and extracellular environment or tumour microenvironment (TME). There is a general understanding of a co-evolution between cancer cells and their surrounding TME, pointing at a functional con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0402f7cf487baee85aa1db0f361dc8
Autor:
Rodriguez-Hernandez, Irene, Maiques, Oscar, Kohlhammer, Leonie, Cantelli, Gaia, Perdrix-Rosell, Anna, Monger, Joanne, Fanshawe, Bruce, Bridgeman, Victoria L., Karagiannis, Sophia N., Penin, Rosa M., Marcolval, Joaquim, Marti, Rosa M., Matias-Guiu, Xavier, Fruhwirth, Gilbert O., Orgaz, Jose L., Malanchi, Ilaria, Sanz-Moreno, Victoria
Publikováno v:
Nature Communications; 10/20/2020, Vol. 11 Issue 1, p1-20, 20p