Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Anna Pegoraro"'
Autor:
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionModified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8+T cell responses are optimally induced, if both, direct- and cross-presentation of viral or recombinant ant
Externí odkaz:
https://doaj.org/article/c51d0799a12d4c9e9a19762506b18869
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6673 (2024)
P2X7 receptor activation by extracellular adenosine triphosphate (eATP) modulates different intracellular pathways, including pro-inflammatory and tumor-promoting cascades. ATP is released by cells and necrotic tissues during stressful conditions and
Externí odkaz:
https://doaj.org/article/1217fa66399344d187d7d1acecb0e911
Autor:
Anna Pegoraro, Valentino Bezzerri, Gloria Tridello, Cecilia Brignole, Francesca Lucca, Emily Pintani, Cesare Danesino, Simone Cesaro, Francesca Fioredda, Marco Cipolli
Publikováno v:
Cancers, Vol 16, Iss 7, p 1420 (2024)
Shwachman–Diamond syndrome (SDS) is one of the most common inherited bone marrow failure syndromes. SDS is characterized by hypocellular bone marrow, with a severe impairment of the myeloid lineage, resulting in neutropenia, thrombocytopenia, and,
Externí odkaz:
https://doaj.org/article/dab3faa8ef6a41b2b8f7f862f5e8886d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13906 (2023)
The tumor niche is an environment rich in extracellular ATP (eATP) where purinergic receptors have essential roles in different cell subtypes, including cancer, immune, and stromal cells. Here, we give an overview of recent discoveries regarding the
Externí odkaz:
https://doaj.org/article/fde7541ea2824c75bc3321bf14fa323d
Autor:
Anna Pegoraro, Elena De Marchi, Manuela Ferracin, Elisa Orioli, Michele Zanoni, Cristian Bassi, Anna Tesei, Marina Capece, Emi Dika, Massimo Negrini, Francesco Di Virgilio, Elena Adinolfi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Abstract Tumor growth and metastatic spreading are heavily affected by the P2X7 receptor as well as microvesicles and exosomes release into the tumor microenvironment. P2X7 receptor stimulation is known to trigger vesicular release from immune and ce
Externí odkaz:
https://doaj.org/article/47d92cf271a542258cc92c6596ad9022
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cancer is a complex disease with a rapid growing incidence and often characterized by a poor prognosis. Although impressive advances have been made in cancer treatments, resistance to therapy remains a critical obstacle for the improvement of patient
Externí odkaz:
https://doaj.org/article/30106975d46545f38f044946293f149a
Autor:
Elena De Marchi, Anna Pegoraro, Roberta Turiello, Francesco Di Virgilio, Silvana Morello, Elena Adinolfi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
ATP and adenosine are key constituents of the tumor niche where they exert opposite and complementary roles. ATP can be released in response to cell damage or actively released by tumor cells and subsequently degraded into adenosine, which accumulate
Externí odkaz:
https://doaj.org/article/e176bc02db0345e7a0589c15adea8acb
Autor:
Abdul Waheed Khan, Antonella Minelli, Annalisa Frattini, Giuseppe Montalbano, Alessia Bogni, Marco Fabbri, Giovanni Porta, Francesco Acquati, Rita Maria Pinto, Elena Bergami, Rossella Mura, Anna Pegoraro, Simone Cesaro, Marco Cipolli, Marco Zecca, Cesare Danesino, Franco Locatelli, Emanuela Maserati, Francesco Pasquali, Roberto Valli
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Background Clonal chromosome changes are often found in the bone marrow (BM) of patients with Shwachman-Diamond syndrome (SDS). The most frequent ones include an isochromosome of the long arm of chromosome 7, i (7)(q10), and an interstitial
Externí odkaz:
https://doaj.org/article/f3bc050564244f20b7a6bcde606e1c8f
Autor:
Giulia D'Arrigo, Martina Gabrielli, Federica Scaroni, Paolo Swuec, Ladan Amin, Anna Pegoraro, Elena Adinolfi, Francesco Di Virgilio, Dan Cojoc, Giuseppe Legname, Claudia Verderio
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Astrocytes‐derived extracellular vesicles (EVs) are key players in glia‐neuron communication. However, whether EVs interact with neurons at preferential sites and how EVs reach these sites on neurons remains elusive. Using optical manipu
Externí odkaz:
https://doaj.org/article/f0b97afff4c5477aa4aa24818d44f083
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The P2X7 receptor is an ion channel gated by the nucleotide ATP, known for its role in immune responses and recently emerging as a critical onco-promoting factor. Lymphocytes, myeloid cells, and their precursors were among the first cells proved to e
Externí odkaz:
https://doaj.org/article/72d5b3c23719449faacb2a038182351d