Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Anna Pędzińska-Betiuk"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ischemic heart disease, associated with high morbidity and mortality, represents a major challenge for the development of drug-based strategies to improve its prognosis. Results of pre-clinical studies suggest that agonists of cannabinoid CB2 recepto
Externí odkaz:
https://doaj.org/article/769fcbe9c8c04276a653c980f63cece5
Autor:
Magdalena Smereczańska, Natalia Domian, Maryla Młynarczyk, Anna Pędzińska-Betiuk, Irena Kasacka
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 84 (2023)
Hypertension is a global civilization disease and one of the most common causes of death in the world. Organ dysfunction is a serious health consequence of hypertension, which involves damage to the heart, kidneys and adrenals. The interaction of rec
Externí odkaz:
https://doaj.org/article/a497a04069104e1db62103861f1b33c9
Autor:
Klaudia Sztolsztener, Karolina Konstantynowicz-Nowicka, Anna Pędzińska-Betiuk, Adrian Chabowski
Publikováno v:
Cells, Vol 12, Iss 18, p 2243 (2023)
Hepatic fibrosis is a consequence of liver injuries, in which the overproduction and progressive accumulation of extracellular matrix (ECM) components with the simultaneous failure of matrix turnover mechanisms are observed. The aim of this study was
Externí odkaz:
https://doaj.org/article/194a90550df4465da6b4440eba8bf914
Autor:
Patryk Remiszewski, Anna Pędzińska-Betiuk, Krzysztof Mińczuk, Eberhard Schlicker, Justyna Klimek, Janusz Dzięcioł, Barbara Malinowska
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pulmonary hypertension (PH) is a disease leading to increased pressure in the pulmonary artery and right heart failure. The adenosine monophosphate-activated protein kinase (AMPK) activator, metformin, has a protective effect against PH. CB1 receptor
Externí odkaz:
https://doaj.org/article/8c70a34cdf564994aea7e6b801aed5a9
Autor:
Jolanta Weresa, Anna Pędzińska-Betiuk, Krzysztof Mińczuk, Barbara Malinowska, Eberhard Schlicker
Publikováno v:
Cells, Vol 11, Iss 7, p 1142 (2022)
The use of cannabis preparations has steadily increased. Although cannabis was traditionally assumed to only have mild vegetative side effects, it has become evident in recent years that severe cardiovascular complications can occur. Cannabis use has
Externí odkaz:
https://doaj.org/article/7f281cd453a5421a92d546d74b941dd8
Autor:
Patryk Remiszewski, Iwona Jarocka-Karpowicz, Michał Biernacki, Anna Jastrząb, Eberhard Schlicker, Marek Toczek, Ewa Harasim-Symbor, Anna Pędzińska-Betiuk, Barbara Malinowska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1295 (2020)
We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats. Hypertension was connected with increases in cardiac and plasma markers of lip
Externí odkaz:
https://doaj.org/article/d361636c66504e8a87a70e7f05a0715b
Autor:
Jolanta Weresa, Barbara Malinowska, Maciej Mitrosz, Anna Pędzińska-Betiuk, Eberhard Schlicker, Grzegorz Hirnle
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:1547-1557
We have previously shown that cannabinoid CB1 and CB2 receptor antagonists, AM251 and AM630, respectively, modulate cardiostimulatory effects of isoprenaline in atria of Wistar rats. The aim of the present study was to examine whether such modulatory
Publikováno v:
European journal of pharmacology. 911
The global incidence of respiratory diseases and complications is increasing. Therefore, new methods of treatment, as well as prevention, need to be investigated. A group of compounds that should be considered for use in respiratory diseases is canna
Publikováno v:
Pharmacological Reports. 71:82-89
Background Drugs targeting CB1 and CB2 receptors have been suggested to possess therapeutic benefit in cardiovascular disorders associated with elevated sympathetic tone. Limited data suggest cannabinoid ligands interact with postsynaptic β-adrenoce
Autor:
Irena Kasacka, Ewa Harasim-Symbor, Anna Pędzińska-Betiuk, Marek Toczek, Bernadetta Gajo, Eberhard Schlicker, Barbara Malinowska, Jolanta Weresa
Publikováno v:
Toxicology and applied pharmacology. 411
Cannabidiol (CBD) is suggested to possess cardioprotective properties. We examined the influence of chronic (10 mg/kg once daily for 2 weeks) CBD administration on heart structure (e.g. cardiomyocyte width) and function (e.g. stimulatory and inhibito