Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anna Oravetzova"'
Autor:
Andra S. Martinikova, Miroslav Stoyanov, Anna Oravetzova, Yannick P. Kok, Shibo Yu, Jana Dobrovolna, Pavel Janscak, Marcel vanVugt, Libor Macurek
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 6-20 (2024)
Oncogene‐induced replication stress has been recognized as a major cause of genome instability in cancer cells. Increased expression of cyclin E1 caused by amplification of the CCNE1 gene is a common cause of replication stress in various cancers.
Externí odkaz:
https://doaj.org/article/bca8c70888bf4c5eb9181c8b76ab63bf
Autor:
Martin Andrs, Henriette Stoy, Barbora Boleslavska, Nagaraja Chappidi, Radhakrishnan Kanagaraj, Zuzana Nascakova, Shruti Menon, Satyajeet Rao, Anna Oravetzova, Jana Dobrovolna, Kalpana Surendranath, Massimo Lopes, Pavel Janscak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Excessive oxidative stress is widely perceived as a key factor in cancer progression. Here, the authors reveal that oxidative stress induces transcription-dependent replication fork stalling that appears to be a major source of chromosomal rearrangem
Externí odkaz:
https://doaj.org/article/745c0a072ad8422ca874cba769fe660b
Autor:
Andra S. Martinikova, Miroslav Stoyanov, Anna Oravetzova, Yannick P. Kok, Shibo Yu, Jana Dobrovolna, Pavel Janscak, Marcel van Vugt, Libor Macurek
Publikováno v:
Molecular Oncology.
Autor:
null Andra S. Martinikova, null Miroslav Stoyanov, null Anna Oravetzova, null Yannick P. Kok, null Shibo Yu, null Jana Dobrovolna, null Pavel Janscak, null Marcel van Vugt, null Libor Macurek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ad7a32bff781c99611837832fa513d
https://doi.org/10.1002/1878-0261.13433/v2/response1
https://doi.org/10.1002/1878-0261.13433/v2/response1
Autor:
Zuzana Nascakova, Vaclav Urban, Barbora Boleslavska, Edita Vlachova, Jana Dobrovolna, Anna Oravetzova, Pavel Janscak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3740, p 3740 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences
Volume 22
Issue 7
R-loops are three-stranded structures generated by annealing of nascent transcripts to the template DNA strand, leaving the non-template DNA strand exposed as a single-stranded loop. Although R-loops play important roles in physiological processes su
Publikováno v:
Genes
Genes, Vol 11, Iss 2, p 232 (2020)
Genes, Vol 11, Iss 2, p 232 (2020)
RECQ5 belongs to the RecQ family of DNA helicases. It is conserved from Drosophila to humans and its deficiency results in genomic instability and cancer susceptibility in mice. Human RECQ5 is known for its ability to regulate homologous recombinatio