Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna Okishima"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Non-invasive delivery of hyaluronan into the stratum corneum (SC) is extremely difficult because of its high molecular weight and the strong barrier of the SC. We developed a safe method of administering hyaluronan into the human SC and dete
Externí odkaz:
https://doaj.org/article/6d30c71a45ce4fdfa9b15450eb6651d1
Autor:
Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu, Kazuhiro Saito, Ikumi Yamauchi, Saki Ariizumi, Yuqi Zhou, Ting-Hui Xiao, Keisuke Goda, Naoto Oku, Tomohiro Asai, Kenneth J. Shea
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Sepsis caused by the release of inflammatory mediators into the blood is a life threatening disease. Here, the authors report on the development of hydrogel nanoparticles for the capture and neutralisation of histones, major inflammatory mediators, a
Externí odkaz:
https://doaj.org/article/eb612ef6ea67468793984170be09b6f2
Autor:
Hiromichi Egami, Naoto Oku, Anna Okishima, Yoshitaka Hamashima, Go Yasuno, Hiroyuki Koide, Yu Hoshino, Tomohiro Asai, Naoki Hayashi
Publikováno v:
Biochemical and Biophysical Research Communications. 561:1-6
Synthetic polymers prepared using several functional monomers have attracted attention as cost-effective protein affinity reagents and alternative to antibodies. We previously reported the synthesis of poly NIPAm-based nanoparticles (NPs) using sever
Autor:
Kenneth J. Shea, Hiroyuki Koide, Saki Ariizumi, Tomohiro Asai, Keiichi Yoshimatsu, Yu Hoshino, Yuri Kamon, Yuqi Zhou, Ikumi Yamauchi, Naoto Oku, Anna Okishima, Kazuhiro Saito, Keisuke Goda, Ting Hui Xiao
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Sepsis is a life-threatening condition caused by the extreme release of inflammatory mediators into the blood in response to infection (e.g., bacterial infection, COVID-19), resulting in the dysfunction of multiple organs. Currently, there is no dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b15baf338ab028849426107cd7f214c
https://escholarship.org/uc/item/152483pj
https://escholarship.org/uc/item/152483pj
Autor:
Hiroyuki Koide, Yu Hoshino, Saki Ariizumi, Anna Okishima, Hiroki Tsuchida, Chiaki Kiyokawa, Masahiko Nakamoto, Tomohiro Asai, Naoto Oku
Publikováno v:
Journal of Controlled Release. 268:335-342
Many of macromolecular toxins induce cell death by directly interacting with cells or induction of inflammatory cytokines. Abiotic polymer ligands (PLs) composed of functional monomers are able to bind and neutralize toxins in vivo and are of great i
Autor:
Anna Okishima, Hiromichi Egami, Yoshitaka Hamashima, Yu Hoshino, Hiroyuki Koide, Naoto Oku, Tomohiro Asai
Publikováno v:
Biomacromolecules. 20(4)
Synthetic polymers are of interest as stable and cost-effective biomolecule-affinity reagents, since these polymers interact with target biomolecules both in vitro and in the bloodstream. However, little has been reported about orally administered po
Autor:
Naoto Oku, Yoshiko Miura, Keiichi Yoshimatsu, Hiroaki Kanazawa, Yu Hoshino, Yuri Nishimura, Yoshitaka Hamashima, Kenneth J. Shea, Tomohiro Asai, Saki Ariizumi, Hiroyuki Koide, Anna Okishima, Takafumi Ide, Hiromichi Egami
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 295
Protein affinity reagents (PARs), frequently antibodies, are essential tools for basic research, diagnostics, separations and for clinical applications. However, there is growing concern about the reproducibility, quality and cost of recombinant and