Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna O. Chertkova"'
Autor:
Franka H. van der Linden, Eike K. Mahlandt, Janine J. G. Arts, Joep Beumer, Jens Puschhof, Saskia M. A. de Man, Anna O. Chertkova, Bas Ponsioen, Hans Clevers, Jaap D. van Buul, Marten Postma, Theodorus W. J. Gadella, Joachim Goedhart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Currently, genetically encoded calcium indicators are not suitable for direct quantification. Here the authors engineer a fluorescence lifetime imaging calcium biosensor, Turquoise Calcium Fluorescence LIfeTime Sensor (Tq-Ca-FLITS), and measure intra
Externí odkaz:
https://doaj.org/article/28e02e090b82435fa3bc07ed281bc827
Publikováno v:
ACS Omega, Vol 5, Iss 6, Pp 2648-2659 (2020)
Externí odkaz:
https://doaj.org/article/e6f6550b3f7948c3af223ee4de28a53a
Autor:
Eike K. Mahlandt, Gabriel Kreider-Letterman, Anna O. Chertkova, Rafael Garcia-Mata, Joachim Goedhart
Rac (herein referring to the Rac family) and Cdc42 are Rho GTPases that regulate the formation of lamellipoda and filopodia, and are therefore crucial in processes such as cell migration. Relocation-based biosensors for Rac and Cdc42 have not been ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebb03178f236d89e06942c6b5960844
Publikováno v:
ACS Omega, 5(6), 2648-2659. American Chemical Society
ACS Omega, Vol 5, Iss 6, Pp 2648-2659 (2020)
ACS Omega, Vol 5, Iss 6, Pp 2648-2659 (2020)
G-protein-coupled receptors (GPCRs) are seven transmembrane spanning receptors that regulate a wide array of intracellular signaling cascades in response to various stimuli. To do so, they couple to different heterotrimeric G proteins and adaptor pro
Autor:
Joachim Goedhart, Jens Puschhof, de Man Sm, Janine J. G. Arts, Anna O. Chertkova, Eike K. Mahlandt, Marten Postma, van Buul Jd, van der Linden Fh, Bas Ponsioen, T. W. J. Gadella, Joep Beumer, Hans Clevers
Publikováno v:
Nature Communications, 12(1). Nature Publishing Group
Nature communications, 12(1):7159. Nature Publishing Group
Nature Communications
Nature Communications, 12:7159. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature communications, 12(1):7159. Nature Publishing Group
Nature Communications
Nature Communications, 12:7159. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The most successful genetically encoded calcium indicators (GECIs) employ an intensity or ratiometric readout. Despite a large calcium-dependent change in fluorescence intensity, the quantification of calcium concentrations with GECIs is problematic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c7ed39a6bb289f2724218075b9172a
https://pure.knaw.nl/portal/en/publications/3acdad4d-db2c-417e-a263-744ab40a2353
https://pure.knaw.nl/portal/en/publications/3acdad4d-db2c-417e-a263-744ab40a2353
Autor:
Elisa Consoli, Tanneke den Blaauwen, Anna O. Chertkova, Nils Y. Meiresonne, Laureen M.Y. Mertens, Joachim Goedhart
Publikováno v:
Molecular Microbiology
Molecular Microbiology, 111(4), 1025-1038. Wiley-Blackwell
Molecular Microbiology, 111(4), 1025-1038. Wiley-Blackwell
Summary Fluorescent proteins (FPs) are of vital importance to biomedical research. Many of the currently available fluorescent proteins do not fluoresce when expressed in non‐native environments, such as the bacterial periplasm. This strongly limit
Publikováno v:
ACS Omega
G-protein-coupled receptors (GPCRs) are seven transmembrane spanning receptors that regulate a wide array of intracellular signaling cascades in response to various stimuli. To do so, they couple to different heterotrimeric G proteins and adaptor pro
Autor:
Peter L. Hordijk, Theodorus W. J. Gadella, Anna O. Chertkova, Sanne van der Niet, Joachim Goedhart, Nathalie R. Reinhard, Marten Postma
The Rho GTPase family is involved in actin dynamics and regulates the barrier function of the endothelium. One of the main barrier-promoting Rho GTPases is Cdc42, also known as cell division control protein 42 homolog. Currently, regulation of Cdc42-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811f225042023f779b3ce1fc20dd2666