Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Anna Norrby-Teglund"'
Autor:
Lea A. Tölken, Antje D. Paulikat, Lana H. Jachmann, Alexander Reder, Manuela Gesell Salazar, Laura M. Palma Medina, Stephan Michalik, Uwe Völker, Mattias Svensson, Anna Norrby-Teglund, Katharina J. Hoff, Michael Lammers, Nikolai Siemens
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background Streptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat and skin to severe invasive infections, such as necrotizing soft tissue infections (NSTIs). Ti
Externí odkaz:
https://doaj.org/article/8cfa48c1af2241b6be605e7677b877f0
Autor:
Patience Shumba, Thomas Sura, Kirsten Moll, Bhavya Chakrakodi, Lea A. Tölken, Jörn Hoßmann, Katharina J. Hoff, Ole Hyldegaard, Michael Nekludov, Mattias Svensson, Per Arnell, Steinar Skrede, INFECT Study Group, Anna Norrby-Teglund, Nikolai Siemens
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-16 (2023)
Abstract Background Streptococcus pyogenes (group A streptococci; GAS) is the main causative pathogen of monomicrobial necrotizing soft tissue infections (NSTIs). To resist immuno-clearance, GAS adapt their genetic information and/or phenotype to the
Externí odkaz:
https://doaj.org/article/32f40f1affed4fa7afada967ae7ea8e8
Autor:
Elin Movert, Jaume Salgado Bolarin, Christine Valfridsson, Jorge Velarde, Steinar Skrede, Michael Nekludov, Ole Hyldegaard, Per Arnell, Mattias Svensson, Anna Norrby-Teglund, Kyu Hong Cho, Eran Elhaik, Michael R. Wessels, Lars Råberg, Fredric Carlsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Variability in disease severity caused by a microbial pathogen is impacted by each infection representing a unique combination of host and pathogen genomes. Here, we show that the outcome of invasive Streptococcus pyogenes infection is regul
Externí odkaz:
https://doaj.org/article/e6892bfbcad24fc4a8d136c2cda1ce1b
Autor:
Laura M. Palma Medina, Haris Babačić, Majda Dzidic, Åsa Parke, Marina Garcia, Kimia T. Maleki, Christian Unge, Magda Lourda, Egle Kvedaraite, Puran Chen, Jagadeeswara Rao Muvva, Martin Cornillet, Johanna Emgård, Kirsten Moll, Karolinska K. I./K. COVID-19 Study Group, Jakob Michaëlsson, Malin Flodström-Tullberg, Susanna Brighenti, Marcus Buggert, Jenny Mjösberg, Karl-Johan Malmberg, Johan K. Sandberg, Sara Gredmark-Russ, Olav Rooyackers, Mattias Svensson, Benedict J. Chambers, Lars I. Eriksson, Maria Pernemalm, Niklas K. Björkström, Soo Aleman, Hans-Gustaf Ljunggren, Jonas Klingström, Kristoffer Strålin, Anna Norrby-Teglund
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform therapeutic decisions. As dysregulated inflammation and coagulation responses have been implicated in the pathoph
Externí odkaz:
https://doaj.org/article/d9502f7d22f248878bad4b825dd78148
Autor:
María I. Quiñones-Vico, Ana Fernández-González, Ana Ubago-Rodríguez, Kirsten Moll, Anna Norrby-Teglund, Mattias Svensson, José Gutiérrez-Fernández, Jesús M. Torres, Salvador Arias-Santiago
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 117 (2024)
Pseudomonas aeruginosa is one of the most common microorganisms causing infections of severe skin wounds. Antibiotic or antiseptic treatments are crucial to prevent and curb these infections. Antiseptics have been reported to be cytotoxic to skin cel
Externí odkaz:
https://doaj.org/article/029dcf8ce7b34f8baeb68005503f8136
Autor:
Sanjeevan Jahagirdar, Lorna Morris, Nirupama Benis, Oddvar Oppegaard, Mattias Svenson, Ole Hyldegaard, Steinar Skrede, Anna Norrby-Teglund, INFECT Study group, Vitor A. P. Martins dos Santos, Edoardo Saccenti
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial infection). These in
Externí odkaz:
https://doaj.org/article/6a62119b012d45339f67890163529c32
Autor:
Dag Harald Skutlaberg, Harald G. Wiker, Haima Mylvaganam, The INFECT Study Group, Anna Norrby-Teglund, Steinar Skrede
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
ObjectivesBiofilm formation has been demonstrated in muscle and soft tissue samples from patients with necrotizing soft tissue infection (NSTI) caused by Streptococcus pyogenes, but the clinical importance of this observation is not clear. Although M
Externí odkaz:
https://doaj.org/article/da454dcb55914e0cb3d4ac8c62df8e9a
Autor:
Nikolai Siemens, Sonja Oehmcke-Hecht, Jörn Hoßmann, Sebastian B. Skorka, Roel H.T. Nijhuis, Corinne Ruppen, Steinar Skrede, Manfred Rohde, Daniel Schultz, Michael Lalk, Andreas Itzek, Dietmar H. Pieper, Christiaan J. van den Bout, Eric C.J. Claas, Ed J. Kuijper, Robert Mauritz, Parham Sendi, Herman F. Wunderink, Anna Norrby-Teglund
Publikováno v:
Journal of Innate Immunity, Pp 1-13 (2019)
A prominent feature of severe streptococcal infections is the profound inflammatory response that contributes to systemic toxicity. In sepsis the dysregulated host response involves both immunological and nonimmunological pathways. Here, we report a
Externí odkaz:
https://doaj.org/article/7a2f0709267c413db0617f3a3d6038e2
Autor:
Robert Thänert, Andreas Itzek, Jörn Hoßmann, Domenica Hamisch, Martin Bruun Madsen, Ole Hyldegaard, Steinar Skrede, Trond Bruun, Anna Norrby-Teglund, INFECT study group, Eva Medina, Dietmar H. Pieper
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Necrotizing soft tissue infections (NSTIs) are caused by a single pathogen such as Streptococcus pyogenes or by multiple bacterial species. Here, the authors integrate microbial community profiling with host and pathogen transcriptional analysis in p
Externí odkaz:
https://doaj.org/article/a71db1a3f33741e88b0fff82cb740d6b
Autor:
Evdoxia Kyriazopoulou, Konstantinos Leventogiannis, Anna Norrby-Teglund, Georgios Dimopoulos, Aikaterini Pantazi, Stylianos E. Orfanos, Nikoletta Rovina, Iraklis Tsangaris, Theologia Gkavogianni, Elektra Botsa, Eleftheria Chassiou, Anastasia Kotanidou, Christina Kontouli, Panagiotis Chaloulis, Dimitrios Velissaris, Athina Savva, Jonas-Sundén Cullberg, Karolina Akinosoglou, Charalambos Gogos, Apostolos Armaganidis, Evangelos J. Giamarellos-Bourboulis, on behalf of the Hellenic Sepsis Study Group
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background A subanalysis of a randomized clinical trial indicated sepsis survival benefit from interleukin (IL)-1 blockade in patients with features of the macrophage activation-like syndrome (MALS). This study aimed to investigate the frequ
Externí odkaz:
https://doaj.org/article/0212585c0a184560bf60ae526a894911