Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anna Niewiadomska-Cimicka"'
Autor:
Jean-Baptiste Pérot, Anna Niewiadomska-Cimicka, Emmanuel Brouillet, Yvon Trottier, Julien Flament
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/06d375aa85d2492a84114e10af070394
Autor:
Anna Niewiadomska-Cimicka, Lorraine Fievet, Magdalena Surdyka, Ewelina Jesion, Céline Keime, Elisabeth Singer, Aurélie Eisenmann, Zaneta Kalinowska-Poska, Hoa Huu Phuc Nguyen, Agnieszka Fiszer, Maciej Figiel, Yvon Trottier
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4354 (2024)
Polyglutamine (polyQ)-encoding CAG repeat expansions represent a common disease-causing mutation responsible for several dominant spinocerebellar ataxias (SCAs). PolyQ-expanded SCA proteins are toxic for cerebellar neurons, with Purkinje cells (PCs)
Externí odkaz:
https://doaj.org/article/4e2d6384325841c7a1537de20931963b
Autor:
Anna Niewiadomska-Cimicka, Antoine Hache, Stéphanie Le Gras, Céline Keime, Tao Ye, Aurelie Eisenmann, Imen Harichane, Michel J. Roux, Nadia Messaddeq, Emmanuelle Clérin, Thierry Léveillard, Yvon Trottier
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-23 (2022)
Abstract Background Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disorder that primarily affects the cerebellum and retina. SCA7 is caused by a polyglutamine expansion in the ATXN7 protein, a subunit of the transcriptional coactivator
Externí odkaz:
https://doaj.org/article/fe31de53419248fabcb1c3dfd9b45723
Autor:
Magdalena Surdyka, Ewelina Jesion, Anna Niewiadomska-Cimicka, Yvon Trottier, Żaneta Kalinowska-Pośka, Maciej Figiel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Adeno-associated virus (AAV)-based brain gene therapies require precision without off-targeting of unaffected neurons to avoid side effects. The cerebellum and its cell populations, including granule and Purkinje cells, are vulnerable to neurodegener
Externí odkaz:
https://doaj.org/article/3406b7d36f2a4eab8c71efb3e63b427c
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Polyglutamine spinocerebellar ataxias (polyQ SCAs) include SCA1, SCA2, SCA3, SCA6, SCA7, and SCA17 and constitute a group of adult onset neurodegenerative disorders caused by the expansion of a CAG repeat sequence located within the coding region of
Externí odkaz:
https://doaj.org/article/3cf891fbc80f4d82a0396b412f013462
Autor:
Ralph Rühl, Agnieszka Krzyżosiak, Anna Niewiadomska-Cimicka, Natacha Rochel, Lajos Szeles, Belén Vaz, Marta Wietrzych-Schindler, Susana Álvarez, Monika Szklenar, Laszlo Nagy, Angel R de Lera, Wojciech Krężel
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005213 (2015)
The retinoid X receptors (RXRs) are ligand-activated transcription factors which heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of (patho)-physiological processes. Although synthetic RXR ligands are developed
Externí odkaz:
https://doaj.org/article/a8a62018524c4643af5c0e9dd6f976d2
Autor:
Magdalena Surdyka, Anna Niewiadomska-Cimicka, Zaneta Kalinowska-Poska, Ewelina Jesion, Elisabeth Singer-Mikosch, Lorraine Fievet, Agnieszka Fiszer, Nicholas S Caron, Michael R Hayden, Huu Phuc Nguyen, Yvon Trottier, Maciej Figiel
Publikováno v:
I: Experimental therapeutics – preclinical.
Autor:
Marion Ciancia, Monika Rataj-Baniowska, Nicolas Zinter, Vito Antonio Baldassarro, Valérie Fraulob, Anne-Laure Charles, Rosana Alvarez, Shin-ichi Muramatsu, Angel R. de Lera, Bernard Geny, Pascal Dollé, Anna Niewiadomska-Cimicka, Wojciech Krężel
Publikováno v:
Progress in neurobiology. 212
Retinoic acid is a powerful regulator of brain development, however its postnatal functions only start to be elucidated. We show that retinoic acid receptor beta (RARβ), is involved in neuroprotection of striatopallidal medium spiny neurons (spMSNs)
Autor:
Chantal Weber, Nadia Messaddeq, Antoine Hache, Frédéric Doussau, Aurélie Eisenmann, Anna Niewiadomska-Cimicka, Marie-France Champy, Yvon Trottier, Michel Roux, Julien Flament, Erwan Grandgirard, Hamid Meziane, Céline Keime, Binnaz Yalcin, Philippe Isope, Alice Karam, Jean-Baptiste Perot, Hoa Huu Phuc Nguyen, Françoise Piguet, Emmanuel Brouillet, Ariana Novati
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
The journal of neuroscience
J Neurosci
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
The journal of neuroscience
J Neurosci
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩
Spinocerebellar ataxia type 7 (SCA7) is an inherited neurodegenerative disease mainly characterized by motor incoordination because of progressive cerebellar degeneration. SCA7 is caused by polyglutamine expansion in ATXN7, a subunit of the transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea85b30c6dc1216aedad93c59f1bc02e
https://hal.science/hal-03378998
https://hal.science/hal-03378998
Autor:
Emmanuel Brouillet, Hoa Huu Phuc Nguyen, Ariana Novati, Marie-France Champy, Nadia Messaddeq, Yvon Trottier, Alice Karam, Erwan Grandgirard, Jean-Baptiste Perot, Julien Flament, Aurélie Eisenmann, Philippe Isope, Françoise Piguet, Antoine Hache, Hamid Meziane, Frédéric Doussau, Céline Keime, Binnaz Yalcin, Anna Niewiadomska-Cimicka, Chantal Weber, Michel Roux
Background Background: Spinocerebellar ataxia type 7 (SCA7) is primarily characterized by progressive cerebellar degeneration with major alteration of Purkinje cells (PC) due to polyglutamine expansion in ATXN7, a subunit of SAGA transcriptional co-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d258ea71db38a726bfe0618f797ce1
https://doi.org/10.21203/rs.3.rs-27474/v1
https://doi.org/10.21203/rs.3.rs-27474/v1