Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Anna Ngo"'
Autor:
Julie Healer, Jennifer K. Thompson, Karen L. Mackwell, Cecille D. Browne, Benjamin A. Seager, Anna Ngo, Kym N. Lowes, Sarah E. Silk, David Pulido, Lloyd D. W. King, Jayne M. Christen, Amy R. Noe, Vinayaka Kotraiah, Paul J. Masendycz, Rajkannan Rajagopalan, Leanne Lucas, Marianne M. Stanford, Lorraine Soisson, Carter Diggs, Robin Miller, Susan Youll, Kaye Wycherley, Simon J. Draper, Alan F. Cowman
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundRH5 is the leading vaccine candidate for the Plasmodium falciparum blood stage and has shown impact on parasite growth in the blood in a human clinical trial. RH5 binds to Ripr and CyRPA at the apical end of the invasive merozoite form, and
Externí odkaz:
https://doaj.org/article/84dce22671ea4ea78f35e3a24b9607b4
Autor:
Meng Ling Choong, Shan Ho Tan, Tuan Zea Tan, Sravanthy Manesh, Anna Ngo, Jacklyn W Y Yong, Henry He Yang, May Ann Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111146 (2014)
Cell lines recapitulate cancer heterogeneity without the presence of interfering tissue found in primary tumor. Their heterogeneous characteristics are reflected in their multiple genetic abnormalities and variable responsiveness to drug treatments.
Externí odkaz:
https://doaj.org/article/a9e5d335f89842119654ded34afd8996
Autor:
William Nguyen, Madeline G. Dans, Iain Currie, Jon Kyle Awalt, Brodie L. Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Penington, Kate E. Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G. Maier, Giel G. van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A. Winzeler, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs
Publikováno v:
ACS Infectious Diseases. 9:668-691
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e68d5adaecdff89fbbd72ee950fe157
https://doi.org/10.1021/acsinfecdis.2c00607
https://doi.org/10.1021/acsinfecdis.2c00607
Autor:
Trent D. Ashton, Madeline G. Dans, Paola Favuzza, Anna Ngo, Adele M. Lehane, Xinxin Zhang, Deyun Qiu, Bikash Chandra Maity, Nirupam De, Kyra A. Schindler, Tomas Yeo, Heekuk Park, Anne-Catrin Uhlemann, Alisje Churchyard, Jake Baum, David A. Fidock, Kate E. Jarman, Kym N. Lowes, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs
Publikováno v:
Journal of Medicinal Chemistry. 66:3540-3565
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1efe0d4900ac4c527f55ae2c93f61fe
https://doi.org/10.1021/acs.jmedchem.2c02092
https://doi.org/10.1021/acs.jmedchem.2c02092
Autor:
Manuel de Lera Ruiz, Paola Favuzza, Zhuyan Guo, Lianyun Zhao, Bin Hu, Zhiyu Lei, Dongmei Zhan, Nicholas Murgolo, Christopher W. Boyce, Marissa Vavrek, Jennifer Thompson, Anna Ngo, Kate E. Jarman, Johnathan Robbins, Justin Boddey, Brad E. Sleebs, Kym N. Lowes, Alan F. Cowman, David B. Olsen, John A. McCauley
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1745-1754
Drug resistance to first-line antimalarials-including artemisinin-is increasing, resulting in a critical need for the discovery of new agents with novel mechanisms of action. In collaboration with the Walter and Eliza Hall Institute and with funding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5c87b18003c3926bf80d926fcdff26
https://doi.org/10.1021/acsmedchemlett.2c00355
https://doi.org/10.1021/acsmedchemlett.2c00355
Autor:
Joshua H, Hill, Jamie, Kuhlman, Aimee, LaRiccia, Anna, Ngo, Sara Jordan, Hyland, Marshall C, Spalding
Publikováno v:
Journal of Trauma Nursing. 29:235-239
Nonsteroidal anti-inflammatory drugs are an effective nonopiate option for pain control. However, the antiplatelet aggregation of cyclooxygenase-1 (COX-1) inhibitors presents a concern in that they may exacerbate bleeding in patients with solid organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c93467bdfc4ec64c4efc120c167c1ce
https://doi.org/10.1097/jtn.0000000000000670
https://doi.org/10.1097/jtn.0000000000000670
Autor:
Lachlan W. Richardson, Trent D. Ashton, Madeline G. Dans, Nghi Nguyen, Paola Favuzza, Tony Triglia, Anthony N. Hodder, Anna Ngo, Kate E. Jarman, Alan F. Cowman, Brad E. Sleebs
Publikováno v:
ChemMedChem. 17(18)
Plasmepsin X (PMX) is an aspartyl protease that processes proteins essential for Plasmodium parasites to invade and egress from host erythrocytes during the symptomatic asexual stage of malaria. PMX substrates possess a conserved cleavage region deno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b486f854b3a922119d8a9f79226a6b71
https://pubmed.ncbi.nlm.nih.gov/35906744
https://pubmed.ncbi.nlm.nih.gov/35906744
Publikováno v:
Food ScienTech Journal, Vol 6, Iss 1, Pp 67-82 (2024)
Foam-mat drying of Ngu using egg white as a foaming agent was investigated. Three concentrations of Ngu sample- 60, 80, and 100% were used for the study. The Ngu samples were enriched with egg white at 20, 25, and 30% concentration respectively at ro
Externí odkaz:
https://doaj.org/article/e8b9a66ab64745c08e87a1bcb31a3a32
Autor:
Petar P.S. Calic, Natalie B. Vinh, Chaille T. Webb, Tess R. Malcolm, Anna Ngo, Kym Lowes, Nyssa Drinkwater, Sheena McGowan, Peter J. Scammells
Publikováno v:
European Journal of Medicinal Chemistry. 248:115051
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8e81b37acfeefd0bf2e8efe87ad93b
https://doi.org/10.1016/j.ejmech.2022.115051
https://doi.org/10.1016/j.ejmech.2022.115051
Autor:
Anthony N. Hodder, Janni Christensen, Stephen Scally, Tony Triglia, Anna Ngo, Richard W. Birkinshaw, Brodie Bailey, Paola Favuzza, Melanie H. Dietrich, Wai-Hong Tham, Peter E. Czabotar, Kym Lowes, Zhuyan Guo, Nicholas Murgolo, Manuel de Lera Ruiz, John A. McCauley, Brad E. Sleebs, David Olsen, Alan F. Cowman
Publikováno v:
Structure (London, England : 1993). 30(7)
Plasmepsins IX (PMIX) and X (PMX) are essential aspartyl proteases for Plasmodium spp. egress, invasion, and development. WM4 and WM382 inhibit PMIX and PMX in Plasmodium falciparum and P. vivax. WM4 inhibits PMX, while WM382 is a dual inhibitor of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6183eb6a0c4dae275459130882bd01a0
https://pubmed.ncbi.nlm.nih.gov/35460613
https://pubmed.ncbi.nlm.nih.gov/35460613