Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anna Nakanishi"'
Autor:
Anna Nakanishi, Satoshi Toyama, Daichi Onozato, Chihiro Watanabe, Tadahiro Hashita, Takahiro Iwao, Tamihide Matsunaga
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 351-361 (2022)
Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by repeated remissions and relapses. Immunosuppressive drugs have facilitated the induction and maintenance of remission in many patients with UC. However, immunosup
Externí odkaz:
https://doaj.org/article/fc4615f9a90e47e0b02a5bd0a10d9f3c
Autor:
Anna Nakanishi, Hiroki Okumura, Tadahiro Hashita, Aya Yamashita, Yuka Nishimura, Chihiro Watanabe, Sakina Kamimura, Sanae Hayashi, Shuko Murakami, Kyoko Ito, Takahiro Iwao, Akari Ikeda, Tomoyasu Hirose, Toshiaki Sunazuka, Yasuhito Tanaka, Tamihide Matsunaga
Publikováno v:
Viruses, Vol 14, Iss 11, p 2468 (2022)
Hepatitis B virus (HBV) specifically infects human hepatocytes and increases the risks of cirrhosis and liver cancer. Currently, nucleic acid analogs are the main therapeutics for chronic hepatitis caused by HBV infection. Although nucleic acid analo
Externí odkaz:
https://doaj.org/article/c8cb069c76e847feb81b286bbed86399
Autor:
Katsunori Nakamura, Takahiro Iwao, Akiko Koeda, Yoko Sakai, Anna Nakanishi, Tamihide Matsunaga, Misaki Yamashita, Shota Mizuno
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:304-312
Herein, we evaluated CYPs and their nuclear receptor mRNA induction by exposure to typical inducers, omeprazole, rifampicin, and phenobarbital in cynomolgus monkey hepatocytes. Six freshly-isolated hepatocytes and 6 cryopreserved hepatocytes from cyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171ce4d8c3e3c3e8f026a3737ca00a41
https://doi.org/10.1016/j.dmpk.2020.03.001
https://doi.org/10.1016/j.dmpk.2020.03.001
Publikováno v:
Drug Metabolism and Disposition. 46:1519-1527
The liver abundantly expresses various drug-metabolizing enzymes and, thus, plays a central role in drug metabolism. In this regard, cytochrome P450 (CYP) is responsible for drug metabolism in the liver. Therefore, since CYP3A4 accounts for approxima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1994a2723798524dcc9164853d311fb
https://doi.org/10.1124/dmd.118.082982
https://doi.org/10.1124/dmd.118.082982
Autor:
Misaki Yamashita, Takahiro Iwao, Daichi Onozato, Takumi Akagawa, Tamihide Matsunaga, Yuriko Kida, Anna Nakanishi, Isamu Ogawa, Tadahiro Hashita
Publikováno v:
Drug Metabolism and Disposition. 46:1572-1580
Intestinal organoids morphologically resemble intestinal tissues and are expected to be used in both regenerative medicine and drug development studies, including pharmacokinetic studies. However, the pharmacokinetic properties of these organoids rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608afed76795b140796b732c0d338b7a
https://doi.org/10.1124/dmd.118.080374
https://doi.org/10.1124/dmd.118.080374
Autor:
Akiko Koeda, Misaki Yamashita, Tamihide Matsunaga, Shota Mizuno, Anna Nakanishi, Katsunori Nakamura, Yoko Sakai, Takahiro Iwao
Publikováno v:
Drug metabolism and pharmacokinetics. 34(4)
In this study, freshly isolated and cryopreserved cynomolgus monkey hepatocytes were seeded on Cell-able® plates with feeder cells to form spheroids and were cultured for 28 days. As a control, hepatocytes were also cultured with or without feeder c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb26f803db7de03f2062809206cc1ea1
https://pubmed.ncbi.nlm.nih.gov/31174977
https://pubmed.ncbi.nlm.nih.gov/31174977
Autor:
Kana Yamada, Tadahiro Hashita, Ichiro Miyoshi, Takahiro Iwao, Tamihide Matsunaga, Anna Nakanishi, Yoh-ichi Tagawa, Mai Yamanoue, Hiroki Okumura, Tomomi Miyamoto, Satoshi Toyama, Akane Ukai, Masumi Hirabayashi
Publikováno v:
Xenotransplantation. 26(1)
The ultimate goal of regenerative medicine is the transplantation of a target organ generated by the patient's own cells. Recently, a method of organ generation using pluripotent stem cells (PSCs) and blastocyst complementation was reported. This app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9384a1bfe352a09a7b3650122e3da3
https://pubmed.ncbi.nlm.nih.gov/30375053
https://pubmed.ncbi.nlm.nih.gov/30375053
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XXXIX-B4, Pp 391-396 (2012)
We focus on the potential of a camera to act as a location sensor, assisting other location sensors to improve positioning accuracy. A camera is installed in almost all mobile devices. Moreover, the camera can be used as a location sensor without add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00bf4fe666cbbf7e8d85227a89b74aa
http://www.int-arch-photogramm-remote-sens-spatial-inf-sci.net/XXXIX-B4/391/2012/isprsarchives-XXXIX-B4-391-2012.pdf
http://www.int-arch-photogramm-remote-sens-spatial-inf-sci.net/XXXIX-B4/391/2012/isprsarchives-XXXIX-B4-391-2012.pdf
Autor:
Anna Nakanishi, Hiroki Okumura, Takahiro Iwao, Tadahiro Hashita, Daichi Onozato, Tamihide Matsunaga
Publikováno v:
Toxicology Letters. 295:S259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa8655d65752b2f4be92f2538a519f23
https://doi.org/10.1016/j.toxlet.2018.06.1052
https://doi.org/10.1016/j.toxlet.2018.06.1052
Autor:
Anna Nakanishi, Eri Nanizawa, Takahiro Iwao, Hiroshi Yukawa, Hiroki Okumura, Yoshinobu Baba, Tadahiro Hashita, Tamihide Matsunaga, Tetsuya Ishikawa
Publikováno v:
Advanced Biosystems. 2:1800137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0754b3f084935b17ce17f9c6235b86d
https://doi.org/10.1002/adbi.201800137
https://doi.org/10.1002/adbi.201800137