Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Minoprio"'
Autor:
Simonetta Palleschi, Valeria Guglielmi, Lorenza Nisticò, Carla Ferreri, Claudio Tabolacci, Francesco Facchiano, Egidio Iorio, Alessandro Giuliani, Sonia Brescianini, Emanuela Medda, Corrado Fagnani, Barbara Rossi, Anna Minoprio, Mattea Chirico, Maria Elena Pisanu, Federica Di Nolfo, Paola Fortini, Valeria Simonelli, Sara Baccarini, Serena Laterza, Tiziana Morretti, Ambra Dell’Orso, Federico Manganello, Paolo Gentileschi, Paolo Sbraccia, Eugenia Dogliotti
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Bariatric surgery (BS) is an effective intervention for severe obesity and associated comorbidities. Although several studies have addressed the clinical and metabolic effects of BS, an integrative analysis of the complex body response to su
Externí odkaz:
https://doaj.org/article/5509d46128f84ae98528b65e691d13b7
Autor:
Francesca Marcon, Roberta Meschini, Egidio Iorio, Simonetta Palleschi, Gabriele De Luca, Ester Siniscalchi, Luigi Conti, Mattea Chirico, Maria Elena Pisanu, Francesca De Battistis, Barbara Rossi, Anna Minoprio, Alessandro Giuliani, Peter Karran, Margherita Bignami
Publikováno v:
Aging cell. 21(7)
hMTH1 protects against mutation during oxidative stress. It degrades 8-oxodGTP to exclude potentially mutagenic oxidized guanine from DNA. hMTH1 expression is linked to ageing. Its downregulation in cultured cells accelerates RAS-induced senescence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d4892d9a7711502d580b1f3a632f79
https://pubmed.ncbi.nlm.nih.gov/35670027
https://pubmed.ncbi.nlm.nih.gov/35670027
Autor:
Filomena Mazzei, Samuel H. Wilson, Piera Cilli, Alberto Martire, Margherita Bignami, Ilenia Ventura, Ettore Meccia, Anna Minoprio
Publikováno v:
Nucleic Acids Research
DNA trinucleotide repeat (TNR) expansion underlies several neurodegenerative disorders including Huntington's disease (HD). Accumulation of oxidized DNA bases and their inefficient processing by base excision repair (BER) are among the factors sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7517aa62fe243d9c2685af3a28e71f4e
http://europepmc.org/articles/PMC4914090
http://europepmc.org/articles/PMC4914090
Autor:
Annapaola Franchitto, Veronica Marabitti, Pietro Pichierri, Sara Rinalducci, Massimo Sanchez, Filomena Mazzei, Ivana Murfuni, Eva Malacaria, Anna Minoprio, Anita Palma, Giusj Monia Pugliese, Lello Zolla
Publikováno v:
Nucleic Acids Research
The MUS81 complex is crucial for preserving genome stability through the resolution of branched DNA intermediates in mitosis. However, untimely activation of the MUS81 complex in S-phase is dangerous. Little is known about the regulation of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcdb796ab88ada264c8f913ae54df59
Autor:
Paola Porcedda, Filomena Mazzei, Barbara Pardini, Simonetta Guarrera, Claudia Giachino, Eugenia Dogliotti, Alessandra Allione, Anna Minoprio, Giuseppe Matullo, Valeria Simonelli, Fulvio Ricceri, Alessia Russo
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Due to the great number of genes involved in DNA repair and the interactions among the pathways responsible for the repair of different types of DNA damage, there is an increasing need for simple and reliable approaches to phenotypically assess DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f30c37d07122c7b30726fbbe6e542a
Autor:
Valeria Simonelli, A. Calcagnile, Alessandro Alimonti, Virgilia Toccaceli, Lorenza Nisticò, Filomena Mazzei, Maria Antonietta Stazi, Anna Minoprio, Emanuela Medda, Alessandro Giuliani, Mariarosaria D’Errico, Eugenia Dogliotti, Luisa Minghetti, Beatrice Bocca
Publikováno v:
Free radical biologymedicine. 97
Inefficient response to oxidative stress has been associated with ageing and health risk. Metals are known to inhibit DNA repair and may modify the antioxidant response. How genetic variability and lifestyle factors modulate the response to oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1671fc138b105877e8f58eac53c087e
https://pubmed.ncbi.nlm.nih.gov/27264237
https://pubmed.ncbi.nlm.nih.gov/27264237
Autor:
Alessandra Allione, Giuseppe Matullo, Filomena Mazzei, Eugenia Dogliotti, Fulvio Ricceri, Anna Minoprio, Mariarosaria D’Errico, Simonetta Guarrera, Ada Funaro, Laura Narciso, Flavia Barone, Valeria Simonelli, Ulla Vogel
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Several lines of evidence suggest an association between oxidative DNA-damage repair capacity and cancer risk. In particular, a DNA-glycosylase assay for removal of 8-oxoguanine (8-oxoG) in peripheral blood mononuclear cells (PBMC) has been successfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee7cc8d21494d82dc84d67ed798b607
https://doi.org/10.1016/j.mrgentox.2010.10.004
https://doi.org/10.1016/j.mrgentox.2010.10.004
Autor:
Antonio Menditto, Barbara Rossi, Anna Minoprio, A. Calibotti, Marina Patriarca, Ferdinando Chiodo, S. Palleschi
Publikováno v:
Microchemical Journal. 67:313-331
The presence of chemicals in the environment is a matter of concern in that it poses potential health risks. At present, exposure to toxic chemicals and their biological and biochemical effects can be better estimated by biological monitoring, throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a5b4de43c764e42e7bf2d2e83d3ed6
https://doi.org/10.1016/s0026-265x(00)00081-3
https://doi.org/10.1016/s0026-265x(00)00081-3
Publikováno v:
Fresenius' Journal of Analytical Chemistry. 360:489-493
Selenium is an essential element which importance for human health is widely recognised. At present, Se status is assessed by either determination of total Se or glutathione peroxidase activity, but increasing attention is paid to the dosage of other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49a00b55fb7559f9e7d6ef18acdb0a9
https://doi.org/10.1007/s002160050746
https://doi.org/10.1007/s002160050746
Autor:
Margherita Bignami, Paola Torreri, Filomena Mazzei, Eleonora Turco, Anna Minoprio, Guglielmina Nadia Ranzani, Ilenia Ventura, Maria Teresa Russo, Sara Molatore, Paolo Degan
Publikováno v:
Nucleic Acids Research
The MUTYH DNA-glycosylase is indirectly engaged in the repair of the miscoding 7,8-dihydro-8-oxo-2'-deoxyguanine (8-oxodG) lesion by removing adenine erroneously incorporated opposite the oxidized purine. Inherited biallelic mutations in the MUTYH ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc99c2ee25f3deb5e0b564136937cd1
https://pubmed.ncbi.nlm.nih.gov/23460202
https://pubmed.ncbi.nlm.nih.gov/23460202