Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anna Mestre Borras"'
Autor:
Sara S. Rinne, Wen Yin, Anna Mestre Borras, Ayman Abouzayed, Charles Dahlsson Leitao, Anzhelika Vorobyeva, John Löfblom, Stefan Ståhl, Anna Orlova, Torbjörn Gräslund
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1293 (2022)
Increasing evidence suggests that therapy targeting the human epidermal growth factor receptor 3 (HER3) could be a viable route for targeted cancer therapy. Here, we studied a novel drug conjugate, ZHER3-ABD-mcDM1, consisting of a HER3-targeting affi
Externí odkaz:
https://doaj.org/article/1b4f2bf682d34017b8552f583cac72d9
Autor:
Alexandros Karyolaimos, Katarzyna Magdalena Dolata, Minia Antelo-Varela, Anna Mestre Borras, Rageia Elfageih, Susanne Sievers, Dörte Becher, Katharina Riedel, Jan-Willem de Gier
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2020)
Recently, we engineered a tunable rhamnose promoter-based setup for the production of recombinant proteins in E. coli. This setup enabled us to show that being able to precisely set the production rate of a secretory recombinant protein is critical t
Externí odkaz:
https://doaj.org/article/5014fd38b9094df5916d75db01b2c05a
Autor:
Alexandros Karyolaimos, Henry Ampah-Korsah, Tamara Hillenaar, Anna Mestre Borras, Katarzyna Magdalena Dolata, Susanne Sievers, Katharina Riedel, Robert Daniels, Jan-Willem de Gier
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Proteins that contain disulfide bonds mainly mature in the oxidative environment of the eukaryotic endoplasmic reticulum or the periplasm of Gram-negative bacteria. In E. coli, disulfide bond containing recombinant proteins are often targeted to the
Externí odkaz:
https://doaj.org/article/cf065360c89a44d694f8a656e485a9f8
Autor:
Charles Dahlsson Leitao, Anna Mestre Borras, Andreas Jonsson, Magdalena Malm, Nina Kronqvist, Filippa Fleetwood, Lisa Sandersjöö, Mathias Uhlén, John Löfblom, Stefan Ståhl, Hanna Lindberg
Publikováno v:
Biochemical and Biophysical Research Communications. 655:75-81
Autor:
Charles Dahlsson Leitao, Anna Mestre Borras, Tianqi Xu, Maryam Oroujeni, Yongsheng Liu, Cornelia Westerberg, Jacob Clinton, Vladimir Tolmachev, Anna Orlova, Stefan Ståhl, Anzhelika Vorobyeva, John Löfblom
Publikováno v:
Journal of Controlled Release. 357:185-195
Publikováno v:
New Biotechnology. 73:9-18
Conditional activation of engineered affinity proteins by proteolytic processing is an interesting approach for a wide range of applications. We have generated an anti-idiotypic masking domain with specificity for the binding surface of an EGFR-targe