Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Anna Mestre"'
Autor:
Javier Fernández, Miquel Lozano, Mireia Torres, Raquel Horrillo, Natalia Afonso, Laura Núñez, Anna Mestre, Alba Pérez, Joan Cid, Montserrat Costa, Vicente Arroyo, Antonio Páez
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101017- (2024)
Background & Aims: Effective treatments for acute-on-chronic liver failure (ACLF) are a major unmet need. This proof-of-concept pilot study was aimed at evaluating the effects of plasma exchange (PE) with albumin 5% (PE-A5%) on albumin functional cap
Externí odkaz:
https://doaj.org/article/09acadea5ed644979941d7457d63500c
Autor:
Raquel Horrillo, Anna Mestre, Alba Pérez, Jordi Vidal, Estefania Alcaraz, Mireia Torres, Vicente Arroyo, Javier Fernández, Joan Clària, Montserrat Costa
Publikováno v:
Annals of Hepatology, Vol 28, Iss , Pp 100907- (2023)
Introduction and Objectives: Non-oncotic albumin functions such as transport, antioxidant and immunomodulatory capacities may be associated with the beneficial effects of albumin therapy in liver disease patients. For acute-on-chronic liver failure (
Externí odkaz:
https://doaj.org/article/b6895e1a5c5649c485edb3e8cc83dcc7
Autor:
Sara S. Rinne, Wen Yin, Anna Mestre Borras, Ayman Abouzayed, Charles Dahlsson Leitao, Anzhelika Vorobyeva, John Löfblom, Stefan Ståhl, Anna Orlova, Torbjörn Gräslund
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1293 (2022)
Increasing evidence suggests that therapy targeting the human epidermal growth factor receptor 3 (HER3) could be a viable route for targeted cancer therapy. Here, we studied a novel drug conjugate, ZHER3-ABD-mcDM1, consisting of a HER3-targeting affi
Externí odkaz:
https://doaj.org/article/1b4f2bf682d34017b8552f583cac72d9
Autor:
Júlia Rodríguez-Comas, Juan Moreno-Vedia, Mercè Obach, Carlos Castaño, Sara de Pablo, Gema Alcarraz-Vizán, Daniela Díaz-Catalán, Anna Mestre, Raquel Horrillo, Montserrat Costa, Anna Novials, Joan-Marc Servitja
Publikováno v:
Molecular Metabolism, Vol 37, Iss , Pp 100984- (2020)
Objective: Pancreatic β-cell failure is central to the development and progression of type 2 diabetes (T2D). The aggregation of human islet amyloid polypeptide (hIAPP) has been associated with pancreatic islet inflammation and dysfunction in T2D. Al
Externí odkaz:
https://doaj.org/article/a5c1a13a452440598ccd2dc0ac96e99b
Autor:
Alexandros Karyolaimos, Katarzyna Magdalena Dolata, Minia Antelo-Varela, Anna Mestre Borras, Rageia Elfageih, Susanne Sievers, Dörte Becher, Katharina Riedel, Jan-Willem de Gier
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2020)
Recently, we engineered a tunable rhamnose promoter-based setup for the production of recombinant proteins in E. coli. This setup enabled us to show that being able to precisely set the production rate of a secretory recombinant protein is critical t
Externí odkaz:
https://doaj.org/article/5014fd38b9094df5916d75db01b2c05a
Autor:
Alexandros Karyolaimos, Henry Ampah-Korsah, Tamara Hillenaar, Anna Mestre Borras, Katarzyna Magdalena Dolata, Susanne Sievers, Katharina Riedel, Robert Daniels, Jan-Willem de Gier
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Proteins that contain disulfide bonds mainly mature in the oxidative environment of the eukaryotic endoplasmic reticulum or the periplasm of Gram-negative bacteria. In E. coli, disulfide bond containing recombinant proteins are often targeted to the
Externí odkaz:
https://doaj.org/article/cf065360c89a44d694f8a656e485a9f8
Autor:
Charles Dahlsson Leitao, Anna Mestre Borras, Andreas Jonsson, Magdalena Malm, Nina Kronqvist, Filippa Fleetwood, Lisa Sandersjöö, Mathias Uhlén, John Löfblom, Stefan Ståhl, Hanna Lindberg
Publikováno v:
Biochemical and Biophysical Research Communications. 655:75-81
Autor:
Charles Dahlsson Leitao, Anna Mestre Borras, Tianqi Xu, Maryam Oroujeni, Yongsheng Liu, Cornelia Westerberg, Jacob Clinton, Vladimir Tolmachev, Anna Orlova, Stefan Ståhl, Anzhelika Vorobyeva, John Löfblom
Publikováno v:
Journal of Controlled Release. 357:185-195
Publikováno v:
New Biotechnology. 73:9-18
Conditional activation of engineered affinity proteins by proteolytic processing is an interesting approach for a wide range of applications. We have generated an anti-idiotypic masking domain with specificity for the binding surface of an EGFR-targe
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