Výsledky vyhledávání - "Anna Mederer"

Maternal inexperience as a risk factor of innate fear and PTSD-like symptoms in mice

Autor: Anna Mederer, Carsten T. Wotjak, Ursula Habersetzer, Anja Siegmund, Florian Holsboer, Maik Dahlhoff, Eckhard Wolf

Publikováno v: Journal of Psychiatric Research. 43:1156-1165

In laboratory rats and mice, differences in maternal care during the first week of life have been shown to exert long-lasting consequences on cognitive functioning and stress processing of the offspring. Such epigenetic programming is also assumed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb45187e97b35abdd896fda16332688
https://doi.org/10.1016/j.jpsychires.2009.02.003

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Distinct behavioral consequences of short-term and prolonged GABAergic depletion in prefrontal cortex and dorsal hippocampus

Autor: Wolfgang Härtig, Jens Grosche, Anna Mederer, Judith M. Reichel, Karola Käfer, Henrik Martens, Rebecca Anders, Dominik Michalski, Gabriela Rogel-Salazar, Carsten T. Wotjak, Benedikt T. Bedenk, Sabine Nissel

Publikováno v: FRONTIERS IN BEHAVIORAL NEUROSCIENCE
Frontiers in behavioral neuroscience
Frontiers in Behavioral Neuroscience, Vol 8 (2015)
Frontiers in Behavioral Neuroscience

GABAergic interneurons are essential for a functional equilibrium between excitatory and inhibitory impulses throughout the CNS. Disruption of this equilibrium can lead to various neurological or neuropsychiatric disorders such as epileptic seizures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dba9f2adeffd499bae281f7008df88
https://hdl.handle.net/11858/00-001M-0000-0029-0320-C11858/00-001M-0000-0029-0322-8

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Trace fear conditioning depends on NMDA receptor activation and protein synthesis within the dorsal hippocampus of mice

Autor: Klaus Wanisch, Jianrong Tang, Anna Mederer, Carsten T. Wotjak

Publikováno v: Behavioural brain research. 157(1)

Various lesion studies demonstrated that trace but not delay fear conditioning requires an intact hippocampal formation. Our present study examined the role of NMDA receptor activation and protein synthesis within the dorsal hippocampus for acquisiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac88d52597710553f51251d7efe6ef2
https://pubmed.ncbi.nlm.nih.gov/15617772

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Disrupted allocentric but preserved egocentric spatial learning in transgenic mice with impaired glucocorticoid receptor function

Autor: Anna Mederer, Magdalena M. Sauvage, Thomas Steckler, Carla Weis, Florian Holsboer

Publikováno v: Behavioural brain research. 100(1-2)

Spatial and non-spatial learning of mice with an incorporated antisense RNA complementary to a fragment of cDNA coding for the glucocorticoid receptor (GR) were evaluated in allocentric and egocentric radial maze and water maze tasks, and in spontane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fa572ab59517c1ae87c55b214aeaca
https://pubmed.ncbi.nlm.nih.gov/10212055

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Behavioural performance in three substrains of mouse strain 129

Autor: Florian Holsboer, Alexandra Montkowski, Anna Mederer, Markus Poettig

Publikováno v: Brain research. 762(1-2)

Recently, the possibility has been raised that the behavioural abnormalities seen in null-mutant mice might be determined by their genetic background rather than by loss of gene function, especially when the 129 mouse strain is used as supplier for e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7ad62b500a80efc696396f6da84c0c
https://pubmed.ncbi.nlm.nih.gov/9262153

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