Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Anna Marie Kenney"'
Autor:
Shubin W. Shahab, Christianna M. Roggeveen, Jiarong Sun, Haritha Kunhiraman, Leon F. McSwain, Kyle Juraschka, Sachin A. Kumar, Olivier Saulnier, Michael D. Taylor, Matthew Schniederjan, Robert W. Schnepp, Tobey J MacDonald, Anna Marie Kenney
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1784-1802 (2023)
Children with Group 3 medulloblastoma (G3 MB) have a very poor prognosis, and many do not survive beyond 5 years after diagnosis. A factor that may contribute to this is the lack of available targeted therapy. Expression of protein lin‐28 homolog B
Externí odkaz:
https://doaj.org/article/93a4f4cb469a4d629a58e2ccc4aa8c54
Autor:
Haritha Kunhiraman, Leon McSwain, Shubin W. Shahab, Timothy R. Gershon, Tobey J. MacDonald, Anna Marie Kenney
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Medulloblastoma (MB) is the most common pediatric brain malignancy and is divided into four molecularly distinct subgroups: WNT, Sonic Hedgehog (SHHp53mut and SHHp53wt), Group 3, and Group 4. Previous reports suggest that SHH MB features a u
Externí odkaz:
https://doaj.org/article/0cd8c8f588934e6087c82e48042e31b0
Autor:
Leon F. McSwain, Kiran K. Parwani, Shubin W. Shahab, Dolores Hambardzumyan, Tobey J. MacDonald, Jennifer M. Spangle, Anna Marie Kenney
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Medulloblastoma (MB) is the most common malignant brain tumor in children with standard of care consisting of surgery, radiation, and chemotherapy. Recent molecular profiling led to the identification of four molecularly distinct MB subgroups – Win
Externí odkaz:
https://doaj.org/article/c595f4316e4c4748b7e37bfac2ab45da
Autor:
Anna Marie Kenney, David C. Pallas, Michael D. Taylor, Sorana A. Morrissy, Victor Maximov, Yun Wei
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af380590c97e815e162e558b54a8822
https://doi.org/10.1158/1541-7786.22515354
https://doi.org/10.1158/1541-7786.22515354
Autor:
Anna Marie Kenney, David C. Pallas, Michael D. Taylor, Sorana A. Morrissy, Victor Maximov, Yun Wei
S1. Nutlin-3a treatment caused apoptosis and cell cycle arrest. S2. Whole blots of MDM2 and p-MDM2S166 in SmoA1 tumors. S3. Normalized expression levels of I2PP2A mRNA in medulloblastoma patients showed a small difference between SHH medulloblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f16ed8ef857068c9102bbf7182ab746
https://doi.org/10.1158/1541-7786.22515351.v1
https://doi.org/10.1158/1541-7786.22515351.v1
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a397ab19633d4864dc36735bdfa522d9
https://doi.org/10.1158/1541-7786.22510972.v1
https://doi.org/10.1158/1541-7786.22510972.v1
Autor:
Anna Marie Kenney, David C. Pallas, Michael D. Taylor, Sorana A. Morrissy, Victor Maximov, Yun Wei
Medulloblastomas, the most common malignant pediatric brain tumors, have been genetically defined into four subclasses, namely WNT-activated, Sonic Hedgehog (SHH)-activated, Group 3, and Group 4. Approximately 30% of medulloblastomas have aberrant SH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a747dc7e56f4839ce51f43cb20f08fe2
https://doi.org/10.1158/1541-7786.c.6541053
https://doi.org/10.1158/1541-7786.c.6541053
Autor:
Michael D. Taylor, Anna Marie Kenney, Carlo M. Croce, James T. Rutka, Timothy Van Meter, Richard Grundy, Yancey Gillespie, Wesia Grajkowska, David W. Ellison, John P. Hagan, Africa Fernandez-L, Paul A. Northcott
Medulloblastoma is the most common malignant pediatric brain tumor, and mechanisms underlying its development are poorly understood. We identified recurrent amplification of the miR-17/92 polycistron proto-oncogene in 6% of pediatric medulloblastomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422c20ab46af1f3609b915d735409a00
https://doi.org/10.1158/0008-5472.c.6499689.v1
https://doi.org/10.1158/0008-5472.c.6499689.v1
Autor:
Anna Marie Kenney, Michael D. Taylor, Eric C. Holland, Jack L. Arbiser, Daniel J. Brat, Baskaran Govindarajan, Dolores Hambardzumyan, Paul A. Northcott, Bobby Bhatia
Supplementary Figure 2 from Tuberous Sclerosis Complex Suppression in Cerebellar Development and Medulloblastoma: Separate Regulation of Mammalian Target of Rapamycin Activity and p27Kip1 Localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349c265d431ca13bb20cdef39cedbb95
https://doi.org/10.1158/0008-5472.22377887.v1
https://doi.org/10.1158/0008-5472.22377887.v1
Autor:
Michael D. Taylor, Anna Marie Kenney, Carlo M. Croce, James T. Rutka, Timothy Van Meter, Richard Grundy, Yancey Gillespie, Wesia Grajkowska, David W. Ellison, John P. Hagan, Africa Fernandez-L, Paul A. Northcott
Supplementary Figure 2 from The miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog–Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehog–Treated Cerebellar Neural Precursors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5441c3ecf150f9f6b6458a1a7695b95a
https://doi.org/10.1158/0008-5472.22380861.v1
https://doi.org/10.1158/0008-5472.22380861.v1