Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Maria Segreti"'
Autor:
Lisa A. Pan, Jane C. Naviaux, Lin Wang, Kefeng Li, Jonathan M. Monk, Sai Sachin Lingampelly, Anna Maria Segreti, Kaitlyn Bloom, Jerry Vockley, Mark A. Tarnopolsky, David N. Finegold, David G. Peters, Robert K. Naviaux
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Peripheral blood metabolomics was used to gain chemical insight into the biology of treatment-refractory Major Depressive Disorder with suicidal ideation, and to identify individualized differences for personalized care. The study cohort con
Externí odkaz:
https://doaj.org/article/68ee96b7a9524fae9d5b610c0a3b414f
Autor:
Lisa A. Pan, Anna Maria Segreti, Joseph Wrobleski, Annie Shaw, Keith Hyland, Marion Hughes, David N. Finegold, Robert K. Naviaux, David A. Brent, Jerry Vockley, David G. Peters
Publikováno v:
Psychological Medicine. :1-9
Background Refractory depression is a devastating condition with significant morbidity, mortality, and societal cost. Approximately 15% of patients with major depressive disorder are refractory to currently available treatments. We hypothesized metab
Autor:
Lisa Pan, Mary L. Phillips, Jay C. Fournier, Anna Maria Segreti, David A. Brent, Henry W. Chase
Publikováno v:
Journal of Medical Psychology. 22:45-54
Background: Functional abnormalities in emotion processing neural circuitry in adolescents with a history of suicide attempt relative to depressed adolescents with no history of suicide and healthy controls have been identified, typically utilizing s
Autor:
Pranali Gandhi, David G. Peters, Anna Maria Segreti, Lisa Pan, Manivel Rengasamy, Lora McClain, David A. Brent
Publikováno v:
Neurology, Psychiatry and Brain Research. 30:39-46
Background Current research suggests that depression is associated with several changes in the immune system, including alterations in inflammatory cytokines, the hypothalamic-pituitary-adrenal axis, and downstream effects on neurotransmitters. Speci
Autor:
Timothy A. Keller, Marcel Adam Just, Lisa Pan, Henry W. Chase, Vladimir L. Cherkassky, David A. Brent, Anna Maria Segreti
Publikováno v:
Journal of Affective Disorders. 212:78-85
The 'default mode network' (DMN), a collection of brain regions including the posterior cingulate cortex (PCC), shows reliable inter-regional functional connectivity at rest. It has been implicated in rumination and other negative affective states, b
Publikováno v:
Journal of affective disorders. 245
The extent to which observed differences in emotion processing and regulation neural circuitry in young adults with current suicidal ideation are paralleled by structural differences is unknown. We measured brain cortical thickness and gray and white
Autor:
Lisa Pan, David A. Brent, Jorge R. C. Almeida, Mary L. Phillips, Natalia L. Lawrence, Anna Maria Segreti, Fabrice Jollant
Publikováno v:
Psychiatry Research: Neuroimaging. 211:112-118
Impairment in decision-making is frequently observed in suicide attempters. Little is known, however, about neural circuitry underlying decision-making in adolescent attempters. Functional magnetic resonance imaging (fMRI) was used to assess decision
Publikováno v:
Psychological Medicine. 43:2129-2142
BackgroundNeural substrates of emotion dysregulation in adolescent suicide attempters remain unexamined.MethodWe used functional magnetic resonance imaging to measure neural activity to neutral, mild or intense (i.e. 0%, 50% or 100% intensity) emotio
Autor:
Jerry Vockley, David A. Brent, Cynthia A. Baca, Robert Steinfeld, Sivan Kassiff, Lisa Pan, Marion A. Hughes, Brian William McKain, Thomas J. Zimmer, Michele Pasquino, Rasim Somer Diler, David G. Peters, Robert K. Naviaux, James M. Perel, David N. Finegold, Keith Hyland, Petra C Martin, Anna Maria Segreti, Manivel Rengasamy, Steven K. Dobrowolski, Nicolette Walano
Publikováno v:
Am J Psychiatry
Treatment-refractory depression is a devastating condition with significant morbidity, mortality, and societal cost. At least 15% of cases of major depressive disorder remain refractory to treatment. The authors previously identified a young adult wi
Publikováno v:
Journal of Child and Adolescent Behaviour. 4
Objective: Early trauma exposure has been demonstrated to significantly impact brain volume. Childhood trauma also contributes to onset of psychopathology, particularly depression. We sought to identify gray matter volume changes unique to trauma exp