Výsledky vyhledávání - "Anna Maria Pertosa"

Cannabinoid Type 1 Receptor Antagonism Delays Ascites Formation in Rats With Cirrhosis

Autor: Marco Domenicali, Paolo Caraceni, A. Principe, T. Croci, Franco Trevisani, Ferdinando Giannone, Andrea Zambruni, Anna Maria Pertosa, Mauro Bernardi

Publikováno v: Gastroenterology. 137:341-349

Endocannabinoids contribute to hemodynamic abnormalities of cirrhosis. Whether this favors renal sodium retention and ascites formation is unknown. We determined whether cannabinoid type 1 receptor antagonism prevents sodium retention and ascites for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6411abdc90a81a636590c896574572
https://doi.org/10.1053/j.gastro.2009.01.004

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Effects of granulocyte colony stimulating-factor in a rat model of acute liver injury

Autor: Lucia Catani, S. Talarico, Marco Domenicali, Roberto M. Lemoli, Mauro Bernardi, Anna Maria Pertosa, A. Principe, Miriam Fogli, Franco Trevisani, Ferdinando Giannone, Paolo Caraceni, Michele Baccarani

Publikováno v: Digestive and Liver Disease. 39:943-951

Background/aim Controversial experimental observations suggest that granulocyte colony stimulating-factor may promote hepatic regeneration after hepatectomy and chemical injury either by directly stimulating adult liver cells or facilitating the mobi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d741339f09009dfe6e6e743d20489c
https://doi.org/10.1016/j.dld.2007.06.005

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Impairment of mitochondrial oxidative phosphorylation in rat fatty liver exposed to preservation-reperfusion injury

Autor: Anna Maria Pertosa, Giovanna Parenti Castelli, Marco Domenicali, Elisabetta Maiolini, Giorgio Lenaz, Mauro Bernardi, Franco Trevisani, Bruno Nardo, Paolo Caraceni, Cristina Bianchi

Publikováno v: Journal of Hepatology. 41:82-88

Background/Aims As the impairment of the cellular energy metabolism contributes to the failure of fatty liver grafts after transplantation, we aimed to determine whether steatosis affects the oxidative phosphorylation activity during preservation. Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a86dc137c0965340f42eaaf99e67248
https://doi.org/10.1016/j.jhep.2004.03.022

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Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischemia-reperfusion injury complicated by endotoxemia

Autor: A. Principe, C Mastroleo, Paolo Caraceni, T. Croci, Ferdinando Giannone, Juan Carlos Cutrin, Maria-Giulia Perrelli, Anna Maria Pertosa, Marco Domenicali, Mauro Bernardi, Franco Trevisani, Ignazio Grattagliano

Background/aim: Endotoxaemia can complicate hepatic ischaemia–reperfusion (IR) injury. Endocannabinoids appear to modulate the haemodynamic alterations and cytokine response induced by lipopolysaccharide (LPS). Thus, we aimed to determine the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167520c8b0d703f4963467bbdbb12a95
http://hdl.handle.net/11585/77271

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Variable activation of phosphoinositide 3-kinase influences the response of liver grafts to ischemic preconditioning

Autor: Matteo Cescon, F. Tuci, Caterina Dal Ponte, Elisa Alchera, Paolo Caraceni, Antonio Daniele Pinna, G. Gasloli, Emanuele Albano, Gian Luca Grazi, Mauro Bernardi, Rita Carini, Anna Maria Pertosa, Chiara Imarisio, Matteo Ravaioli

Publikováno v: Journal of hepatology. 50(5)

Background/Aims The efficacy of ischemic preconditioning (IPC) in preventing reperfusion injury in human liver transplants is still questioned. Phosphoinositide-3-kinase (PI3K) is essential for IPC development in rodent livers. This work investigates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852cd019cbf0cc68e71c96227f857843
https://pubmed.ncbi.nlm.nih.gov/19303157

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Successful treatment of CCL4-induced acute liver failure with portal vein arterialization in the rat

Autor: Paolo Caraceni, Bruno Nardo, Anna Maria Pertosa, Marco Domenicali, Graziella Angiolini, Lorenza Puviani, Antonino Cavallari, Pasquale Chieco, Franco Trevisani, Mauro Bernardi, M. Pariali

Background Optimization of the conditions for regeneration is a major goal in the management of patients with acute liver failure (ALF). Previous observations suggested that hyperoxygenation of the liver may improve its regenerative capacity. Thus, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a673c2bbbee74227768b064f7cfcbb0
http://hdl.handle.net/11585/30266

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Portal vein arterialization for the treatment of post resection acute liver failure in the rat

Autor: Marco Domenicali, Pasquale Chieco, Paolo Caraceni, D. Prezzi, V. Pacilè, Lorenza Puviani, Flavia Neri, Matvey Tsivian, Paolo Beltempo, Mauro Bernardi, M. Pariali, Bruno Nardo, Riccardo Bertelli, Antonino Cavallari, Giuseppe Cavallari, Anna Maria Pertosa, Graziella Angiolini

Introduction Hyperoxygenation of the liver has been suggested to improve its regenerative capacity. Thus, this study sought to determine whether an additional supply of oxygenated blood delivered by portal vein arterialization (PVA) was protective ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae98bb58cb832b4b7519b62ff73136b
http://hdl.handle.net/11585/28318

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A novel sodium overload test predicting ascites decompensation in rats with CCl4-induced cirrhosis

Autor: Marco Domenicali, Anna Maria Pertosa, Paolo Caraceni, Wladimiro Jiménez, Pasquale Chieco, Josefa Ros, A. Principe, Mauro Bernardi, Franco Trevisani

Background/Aims We aimed to develop a non-invasive test to identify the initial alterations of sodium homeostasis and prospectively predict decompensation in preascitic cirrhotic rats. Methods The sodium overload test (SOT) was performed in control (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda4e059df6876e7e5807baf92389af2
http://hdl.handle.net/11585/5466

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Oxidative injury in rat fatty liver exposed to ischemia-reperfusion is modulated by nutritional status

Autor: Paolo Caraceni, Franco Trevisani, Ignazio Grattagliano, Gianluigi Vendemiale, A. Principe, Marco Domenicali, Mauro Bernardi, Anna Maria Pertosa, Antonella Viola, Emanuele Altomare, Gaetano Serviddio, Bruno Nardo

Background and aims. Oxidative stress contributes to ischemia-reperfusion injury in fatty livers. This study aimed to determine whether glycogen depletion influences this oxidative injury and whether the administration of glucose can be protective. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97357c98874f39132a4f81893e6b9d9d
http://hdl.handle.net/11585/5579

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The nutritional status modulates preservation-reperfusion injury in rat fatty liver

Autor: Giuseppe Palasciano, Mauro Bernardi, Ignazio Grattagliano, Marco Domenicali, Paolo Caraceni, Elisabetta Maiolini, Anna Maria Pertosa, A. Principe, Franco Trevisani

Publikováno v: The Journal of surgical research. 127(2)

Background Microcirculation disturbances are essential factors of preservation injury in fatty liver. However, hepatocyte injury is also markedly excessive in fatty liver resulting, at least in part, from energy metabolism impairment and oxidative st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dafcb685032ee9e4711eb3c07f924c
https://pubmed.ncbi.nlm.nih.gov/16083755

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