Zobrazeno 1 - 10 of 67 pro vyhledávání: '"Anna Maria Mileo"'
2
Akademický článek
The αMSH-Dependent PI3K Pathway Supports Energy Metabolism, via Glucose Uptake, in Melanoma Cells
Autor: Giorgia Cardinali, Daniela Kovacs, Sarah Mosca, Barbara Bellei, Enrica Flori, Aldo Morrone, Anna Maria Mileo, Vittoria Maresca
Publikováno v: Cells, Vol 12, Iss 7, p 1099 (2023)
Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention. We performed cellular and molecular biology assays (Western blot, FACS, immunofluo
Externí odkaz: https://doaj.org/article/993c6cb220b14dc9b612695a2a85ae7c
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3
Akademický článek
Tumor Microenvironmental Cytokines Drive NSCLC Cell Aggressiveness and Drug-Resistance via YAP-Mediated Autophagy
Autor: Paola Matarrese, Rosa Vona, Barbara Ascione, Camilla Cittadini, Annalisa Tocci, Anna Maria Mileo
Publikováno v: Cells, Vol 12, Iss 7, p 1048 (2023)
Dynamic reciprocity between cellular components of the tumor microenvironment and tumor cells occurs primarily through the interaction of soluble signals, i.e., cytokines produced by stromal cells to support cancer initiation and progression by regul
Externí odkaz: https://doaj.org/article/5a0979c27a48490ab7b71b85a8388f49
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4
Akademický článek
Polyphenols: Immunomodulatory and Therapeutic Implication in Colorectal Cancer
Autor: Anna Maria Mileo, Paola Nisticò, Stefania Miccadei
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Polyphenolic compounds, widely present in fruits, vegetables, and cereals, have potential benefits for human health and are protective agents against the development of chronic/degenerative diseases including cancer. More recently these bioactive mol
Externí odkaz: https://doaj.org/article/f6154e3f807940ed8cc0769f6a949a60
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5
Artichoke polyphenols sensitize human breast cancer cells to chemotherapeutic drugs via a ROS-mediated downregulation of flap endonuclease 1
Autor: Stefania Miccadei, Stefania Mardente, Donato Di Venere, Anna Maria Mileo
Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative medicine and cellular longevity (Online) 2020 (2020): 1–11. doi:10.1155/2020/7965435
info:cnr-pdr/source/autori:Mileo, Anna Maria; Di Venere, Donato; Mardente, Stefania; Miccadei, Stefania/titolo:Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1/doi:10.1155%2F2020%2F7965435/rivista:Oxidative medicine and cellular longevity (Online)/anno:2020/pagina_da:1/pagina_a:11/intervallo_pagine:1–11/volume:2020
Oxidative Medicine and Cellular Longevity
Combined treatment of several natural polyphenols and chemotherapeutic agents is more effective comparing to the drug alone in inhibiting cancer cell growth. Polyphenolic artichoke extracts (AEs) have been shown to have anticancer properties by trigg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2909199a61d8fc4e4597ea92825f2d
http://hdl.handle.net/11573/1555334
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6
The PI3K pathway induced by αMSH exerts a negative feedback on melanogenesis and contributes to the release of pigment
Autor: Giorgia Cardinali, Vittoria Maresca, Stefania Briganti, Sarah Mosca, Enrica Flori, Anna Maria Mileo, Irene Bottillo
Publikováno v: Pigment cellmelanoma researchREFERENCES. 34(1)
The melanocortin-1 receptor (MC1R) belongs to the family of the G protein-coupled receptor (GPCR). Activated GPCRs can promote the phosphoinositide 3-kinase (PI3K) pathway. Few studies deal with the role of the PI3K pathway activation in response to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc671b5ea321c7eff144274ef9d74aba
https://pubmed.ncbi.nlm.nih.gov/32608114
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7
Microtubule-Based Mitochondrial Dynamics as a Valuable Therapeutic Target in Cancer
Autor: Paola Matarrese, Anna Maria Mileo, Rosa Vona
Publikováno v: Cancers, Vol 13, Iss 5812, p 5812 (2021)
Cancers
Simple Summary Mitochondria are well known for being the powerhouses of the cell—whether the cell is normal or cancerous. Moreover, they can move, split, fuse themselves, or be eliminated via mitophagy with the help of the interplay between motor p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e30528b2f3f0c238056bde20dea498
https://doi.org/10.3390/cancers13225812
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8
The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells
Autor: Silvia Schenone, Giovanni Sette, Rosario Amato, Francesca Musumeci, Michele Signore, Anna Maria Mileo, Gabriele De Luca, Stefania Miccadei, Tobias L. Haas, Carmine Maria Carapella, Silvia Matteoni, Nicola Perrotti, Claudia Abbruzzese, Paola Matarrese, Marco G. Paggi
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Background Glioblastoma multiforme (GBM), due to its location, aggressiveness, heterogeneity and infiltrative growth, is characterized by an exceptionally dismal clinical outcome. The small molecule SI113, recently identified as a SGK1 inhibitor, has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eedba9020ea7189cbaecf0d2959dcfd
http://hdl.handle.net/11567/983598
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9
Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis
Autor: Barbara Ascione, Paola Matarrese, Rosa Vona, Anna Maria Mileo, Marco G. Paggi
Publikováno v: Cancers
Volume 13
Issue 2
Cancers, Vol 13, Iss 353, p 353 (2021)
Human papillomavirus 16 (HPV16) exhibits a strong oncogenic potential mainly in cervical, anogenital and oropharyngeal cancers. The E6 and E7 viral oncoproteins, acting via specific interactions with host cellular targets, are required for cell trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dfcee1364e116e1ce981075aee71f4
https://doi.org/10.3390/cancers13020353
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10
Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness
Autor: Rosa Vona, Paolo Visca, Maria Benevolo, Walter Malorni, Barbara Ascione, Claudia Abbruzzese, Marco G. Paggi, Anna Maria Mileo, Paola Matarrese, Francesca Rollo
Publikováno v: Oncotarget
// Paola Matarrese 1, * , Claudia Abbruzzese 2, * , Anna Maria Mileo 3, * , Rosa Vona 1 , Barbara Ascione 1 , Paolo Visca 4 , Francesca Rollo 4 , Maria Benevolo 4 , Walter Malorni 1, 5 , Marco G. Paggi 2 1 Department of Therapeutic Research and Medic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00410375f531cbaa60c68f67a34a4de
http://europepmc.org/articles/PMC5239452
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