Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Anna Maria Colangelo"'
Autor:
Michele Cerasuolo, Irene Di Meo, Maria Chiara Auriemma, Francesca Trojsi, Maria Ida Maiorino, Mario Cirillo, Fabrizio Esposito, Rita Polito, Anna Maria Colangelo, Giuseppe Paolisso, Michele Papa, Maria Rosaria Rizzo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9637 (2023)
Neurodegeneration is a multifactorial process that involves multiple mechanisms. Examples of neurodegenerative diseases are Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, prion diseases such as Creutzfeldt–Jakob’s disease, and
Externí odkaz:
https://doaj.org/article/257b59191e3f4fea8395cd608baba16c
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 861 (2023)
Alzheimer’s disease (AD) is a progressive and degenerative disease producing the most common type of dementia worldwide. The main pathogenetic hypothesis in recent decades has been the well-known amyloidogenic hypothesis based on the involvement of
Externí odkaz:
https://doaj.org/article/b8d7c47b40a24fe4ad570e3244fb49fd
Autor:
Daniela Gaglio, Marcella Bonanomi, Silvia Valtorta, Rohit Bharat, Marilena Ripamonti, Federica Conte, Giulia Fiscon, Nicole Righi, Elisabetta Napodano, Federico Papa, Isabella Raccagni, Seth J. Parker, Ingrid Cifola, Tania Camboni, Paola Paci, Anna Maria Colangelo, Marco Vanoni, Christian M. Metallo, Rosa Maria Moresco, Lilia Alberghina
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Rewiring of metabolism induced by oncogenic K-Ras in cancer cells involves both glucose and glutamine utilization sustaining enhanced, unrestricted growth. The development of effective anti-cancer treatments targeting metabolism m
Externí odkaz:
https://doaj.org/article/b636cbe034f24a9c849f00374a90e0c7
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 2, Pp 201-205 (2019)
The recognition that neurogenesis does not stop with adolescence has spun off research towards the reduction of brain disorders by enhancing brain regeneration. Adult neurogenesis is one of the tougher problems of developmental biology as it requires
Externí odkaz:
https://doaj.org/article/6521158b18d44771a01b00fde6bfc43b
Autor:
Assunta Virtuoso, Anna Maria Colangelo, Nicola Maggio, Uri Fennig, Nitai Weinberg, Michele Papa, Ciro De Luca
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11304 (2021)
The spatial and temporal coordination of each element is a pivotal characteristic of systems, and the central nervous system (CNS) is not an exception. Glial elements and the vascular interface have been considered more recently, together with the ex
Externí odkaz:
https://doaj.org/article/30b5a56ef4394cdeb3b29ec3fa5881a8
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7554 (2020)
Stroke is a major challenge in modern medicine and understanding the role of the neuronal extracellular matrix (NECM) in its pathophysiology is fundamental for promoting brain repair. Currently, stroke research is focused on the neurovascular unit (N
Externí odkaz:
https://doaj.org/article/8362edd55d7441f0b8de2630f805fe78
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1539 (2020)
The synaptic cleft has been vastly investigated in the last decades, leading to a novel and fascinating model of the functional and structural modifications linked to synaptic transmission and brain processing. The classic neurocentric model encompas
Externí odkaz:
https://doaj.org/article/d0e59ffae83c44afbd264bcba4b7909b
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Coagulation and the immune system interact in several physiological and pathological conditions, including tissue repair, host defense, and homeostatic maintenance. This network plays a key role in diseases of the central nervous system (CNS) by invo
Externí odkaz:
https://doaj.org/article/9bc09032e123412d924df5420227fd12
Autor:
Giovanni Cirillo, Anna Maria Colangelo, Ciro De Luca, Leonilde Savarese, Maria Rosaria Barillari, Lilia Alberghina, Michele Papa
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152750 (2016)
Modulation of extracellular matrix (ECM) remodeling after peripheral nerve injury (PNI) could represent a valid therapeutic strategy to prevent maladaptive synaptic plasticity in central nervous system (CNS). Inhibition of matrix metalloproteinases (
Externí odkaz:
https://doaj.org/article/283d5a37f02b445b86dd7ae013a0e7b8
Autor:
Giovanni Cirillo, Maria Rosaria Bianco, Anna Maria Colangelo, Carlo Cavaliere, De Luca Daniele, Laura Zaccaro, Lilia Alberghina, Michele Papa
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 3, Pp 630-639 (2011)
Reactive gliosis has been implicated in both inflammatory and neurodegenerative diseases. However, mechanisms by which astrocytic activation affects synaptic efficacy have been poorly elucidated. We have used the spared nerve injury (SNI) of the scia
Externí odkaz:
https://doaj.org/article/43c442691be1450fb8e203312880925a