Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Anna Maria Caccuri"'
Autor:
Diego Sbardella, Grazia Raffaella Tundo, Alice Mecchia, Camilla Palumbo, Maria Grazia Atzori, Lauretta Levati, Alessandra Boccaccini, Anna Maria Caccuri, Paolo Cascio, Pedro Miguel Lacal, Grazia Graziani, Monica Varano, Massimiliano Coletta, Mariacristina Parravano
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-21 (2022)
Key Points High glucose quickly induces an atypical NF-kB pro-inflammatory program. CamKII phosphorylation of Rpt6 subunit of the proteasome stimulates IkBα turnover and p65-p50 release. Inhibition of either CamkII or proteasome blocks this pathway.
Externí odkaz:
https://doaj.org/article/2be4c18062b14db4b2e146a57820f67c
Autor:
Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D’Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2128-2138 (2021)
Influenza viruses represent a major threat to human health and are responsible for seasonal epidemics, along with pandemics. Currently, few therapeutic options are available, with most drugs being at risk of the insurgence of resistant strains. Hence
Externí odkaz:
https://doaj.org/article/ecff4c5a42794137b561ff775ca35eb0
Autor:
Veronica Di Paolo, Chiara Fulci, Dante Rotili, Francesca Sciarretta, Alessia Lucidi, Blasco Morozzo della Rocca, Anastasia De Luca, Antonio Rosato, Luigi Quintieri, Anna Maria Caccuri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1131-1139 (2019)
The antitumor agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (1) is a potent inhibitor of GSTP1-1, a glutathione S-transferase capable of inhibiting apoptosis by binding to JNK1 and TRAF2. We recently demonstrated that, unlike its par
Externí odkaz:
https://doaj.org/article/7658832476ab4c16a9cb9de4edf953e6
Publikováno v:
Symmetry, Vol 14, Iss 4, p 720 (2022)
TNF Receptor-Associated Factor 2 (TRAF2) is a homo-trimer belonging to the TNF-receptor-associated factor family (TRAFs). The TRAF2 oligomeric state is crucial for receptor binding, the interaction with other proteins (involved in the TNFR signaling)
Externí odkaz:
https://doaj.org/article/061f7d714732422c84be9eb24818dd80
Autor:
Giulia Siciliano, Veronica Di Paolo, Dante Rotili, Rossella Migale, Francesca Pedini, Marialuisa Casella, Serena Camerini, Daniele Dalzoppo, Rob Henderson, Tonnie Huijs, Koen J. Dechering, Antonello Mai, Anna Maria Caccuri, Marco Lalle, Luigi Quintieri, Pietro Alano
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 168 (2022)
This work describes the activity of 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX) and of its newly identified carboxylic acid metabolite on the human malaria parasite Plasmodium falciparum. NBDHEX has been previously identified as
Externí odkaz:
https://doaj.org/article/a949dc021e86479e8207123ad14c5b58
Autor:
Massimo Serra, Piero Picci, Katia Scotlandi, Anna Maria Caccuri, Monia Zuntini, Claudia Maria Hattinger, Isabella Scionti, Francesca Michelacci, Michela Pasello
Supplementary Table 1 from Overcoming Glutathione S-Transferase P1–Related Cisplatin Resistance in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a395ed0e96fb17a04e7f9802008d5a19
https://doi.org/10.1158/0008-5472.22375092
https://doi.org/10.1158/0008-5472.22375092
Autor:
Massimo Serra, Piero Picci, Katia Scotlandi, Anna Maria Caccuri, Monia Zuntini, Claudia Maria Hattinger, Isabella Scionti, Francesca Michelacci, Michela Pasello
Supplementary Figure 2 from Overcoming Glutathione S-Transferase P1–Related Cisplatin Resistance in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6840607e318583a261367462484ac37a
https://doi.org/10.1158/0008-5472.22375098.v1
https://doi.org/10.1158/0008-5472.22375098.v1
Autor:
Massimo Serra, Piero Picci, Katia Scotlandi, Anna Maria Caccuri, Monia Zuntini, Claudia Maria Hattinger, Isabella Scionti, Francesca Michelacci, Michela Pasello
Supplementary Figure and Table Legends from Overcoming Glutathione S-Transferase P1–Related Cisplatin Resistance in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93bc70d05a499bb28e9ade60cf65c162
https://doi.org/10.1158/0008-5472.22375095
https://doi.org/10.1158/0008-5472.22375095
Autor:
Massimo Serra, Piero Picci, Katia Scotlandi, Anna Maria Caccuri, Monia Zuntini, Claudia Maria Hattinger, Isabella Scionti, Francesca Michelacci, Michela Pasello
Cisplatin (cis-diamminedichloroplatinum, CDDP) is one of the most used drugs for osteosarcoma chemotherapy. By using a series of CDDP-resistant variants, which were established from the U-2OS and Saos-2 human osteosarcoma cell lines, we found that CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9643291d52d7731c7b21ef50846128ea
https://doi.org/10.1158/0008-5472.c.6497706
https://doi.org/10.1158/0008-5472.c.6497706
Autor:
Massimo Serra, Piero Picci, Katia Scotlandi, Anna Maria Caccuri, Monia Zuntini, Claudia Maria Hattinger, Isabella Scionti, Francesca Michelacci, Michela Pasello
Supplementary Figure 1 from Overcoming Glutathione S-Transferase P1–Related Cisplatin Resistance in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7d7fe936855ca15cf591000240a538
https://doi.org/10.1158/0008-5472.22375101.v1
https://doi.org/10.1158/0008-5472.22375101.v1