Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anna Mari Lone"'
Autor:
Anna Mari Lone, Mathias Leidl, Amanda K McFedries, James W Horner, John Creemers, Alan Saghatelian
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89160 (2014)
Genetic studies of rare diseases can identify genes of unknown function that strongly impact human physiology. Prolyl endopeptidase-like (PREPL) is an uncharacterized member of the prolyl peptidase family that was discovered because of its deletion i
Externí odkaz:
https://doaj.org/article/a4ca87502af746049f7ca21b6fbe9a60
Autor:
Anna Mari Lone, Kjetil eTaskén
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Eicosanoids are inflammatory mediators primarily generated by hydrolysis of membrane phospholipids by phospholipase A2 to ω-3 and ω-6 C-20 fatty acids that next are converted to leukotrienes (LTs), prostaglandins (PGs), prostacyclins (PCs) and thro
Externí odkaz:
https://doaj.org/article/b42570025d41400480a761ea3f7e7b41
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68638 (2013)
Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has
Externí odkaz:
https://doaj.org/article/2b6d4d87c2b34d7bbc7eabed1dd98c1c
Autor:
Kjetil Taskén, Albert J. R. Heck, Piero Giansanti, Anna Mari Lone, Aurelien Dugourd, Enio Gjerga, Julio Saez-Rodriguez, Marthe Jøntvedt Jørgensen, Arjen Scholten
Publikováno v:
Science Signaling
Science Signaling, 14(703), 1. American Association for the Advancement of Science
Science Signaling, 14(703), 1. American Association for the Advancement of Science
Prostaglandin E2 (PGE2) promotes an immunosuppressive microenvironment in cancer, partly by signaling through four receptors (EP1, EP2, EP3, and EP4) on T cells. Here, we comprehensively characterized PGE2 signaling networks in helper, cytotoxic, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241d3d22a45fbac87ab5d9565018a9c1
https://dspace.library.uu.nl/handle/1874/413152
https://dspace.library.uu.nl/handle/1874/413152
Autor:
Anna Mari Lone, Kjetil Taskén
Prostaglandin E2 (PGE2) is a key lipid mediator in health and disease, and serves as a crucial link between the immune response and cancer. With the advent of cancer therapies targeting PGE2 signaling pathways at different levels, there has been incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b67079b372f622bbe77b835a227320
http://hdl.handle.net/10852/90239
http://hdl.handle.net/10852/90239
Autor:
Anna Mari, Lone, Kjetil, Taskén
Publikováno v:
Molecular pharmacology. 99(5)
Prostaglandin E
Autor:
Albert J. R. Heck, Enio Gjerga, Kjetil Taskén, Arjen Scholten, Marthe Jøntvedt Jørgensen, Aurelien Dugourd, Piero Giansanti, Anna Mari Lone, Julio Saez-Rodriguez
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Nature Protocols. 8:1730-1742
Identifying the peptidases that inactivate bioactive peptides (e.g., peptide hormones and neuropeptides) in mammals is an important unmet challenge. This protocol describes a recent approach that uses liquid chromatography-mass spectrometry (LC-MS) p
Autor:
Alan Saghatelian, Peter Chase, Daniel A. Bachovchin, Anna Mari Lone, Hugh Rosen, Timothy P. Spicer, Anna E Speers, Peter Hodder, Benjamin F. Cravatt, David B. Westwood, Virneliz Fernandez-Vega
Publikováno v:
Journal of the American Chemical Society. 133:11665-11674
Peptidases play vital roles in physiology through the biosynthesis, degradation, and regulation of peptides. Prolyl endopeptidase-like (PREPL) is a newly described member of the prolyl peptidase family, with significant homology to mammalian prolyl e
Publikováno v:
The AAPS Journal. 12:483-491
The prolyl peptidases are a family of enzymes characterized by a biochemical preference for cleaving proline-containing peptides. The members of this enzyme family include prolyl endopeptidase, prolyl endopeptidase-like, dipeptidyl peptidase 4 (DPP4)