Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Anna Mandinova"'
Autor:
Jong Ho Park, Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin, Jun Wang, Michael R. Collier, Krishna S. Tummala, Anna Mandinova, Nabeel Bardeesy, Yevgeniy R. Semenov, Mari Mino-Kenudson, Shadmehr Demehri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Chronic inflammation is a major cause of cancer worldwide. Interleukin 33 (IL-33) is a critical initiator of cancer-prone chronic inflammation; however, its induction mechanism by environmental causes of chronic inflammation is unknown. Here
Externí odkaz:
https://doaj.org/article/e2b006d3a3b94b3d96580a3db87ec074
Autor:
Eunjeong Kwon, Kristina Todorova, Jun Wang, Rastislav Horos, Kevin K. Lee, Victor A. Neel, Gian Luca Negri, Poul H. Sorensen, Sam W. Lee, Matthias W. Hentze, Anna Mandinova
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The integrity of the stratified epithelia relies on controlled cell turnover but it is unclear how mRNA binding proteins regulates this. Here, the authors show that the RNA binding protein Y-box binding protein-1 translationally represses cytokines,
Externí odkaz:
https://doaj.org/article/ae77c37590464e83bc58037121dc3a32
Autor:
So-Young Hwang, Xianming Deng, Sanguine Byun, Chan Lee, Seung-Joo Lee, Hyunsuk Suh, Jianming Zhang, Qiaofeng Kang, Ting Zhang, Kenneth D. Westover, Anna Mandinova, Sam W. Lee
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 28-36 (2016)
The Wnt/β-catenin signaling pathway plays a major role in tissue homeostasis, and its dysregulation can lead to various human diseases. Aberrant activation of β-catenin is oncogenic and is a critical driver in the development and progression of hum
Externí odkaz:
https://doaj.org/article/31e97cce0bce42708f093a7737416084
Autor:
Takushi Namba, Fang Tian, Kiki Chu, So-Young Hwang, Kyoung Wan Yoon, Sanguine Byun, Masatsugu Hiraki, Anna Mandinova, Sam W. Lee
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 331-339 (2013)
Resolved endoplasmic reticulum (ER) stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis. Here, we show that a proapoptotic p53 target, CDIP1, acts as a key signal transducer of ER-stress-m
Externí odkaz:
https://doaj.org/article/88434e77590541859cb2fb2f08ce392b
Autor:
Scott B Vafai, Emily Mevers, Kathleen W Higgins, Yevgenia Fomina, Jianming Zhang, Anna Mandinova, David Newman, Stanley Y Shaw, Jon Clardy, Vamsi K Mootha
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162686 (2016)
Deficiency of mitochondrial complex I is encountered in both rare and common diseases, but we have limited therapeutic options to treat this lesion to the oxidative phosphorylation system (OXPHOS). Idebenone and menadione are redox-active molecules c
Externí odkaz:
https://doaj.org/article/1189c546b7fa4d0dbe61eebbf1fa260a
Publikováno v:
JAMA Dermatology.
This case-control study examines the type, location, and density of tumor-infiltrating lymphocytes in adult patients with vs without metastatic cutaneous squamous cell carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9061e182a5ee09746bd90aaa0b0dcdc
https://doi.org/10.1001/jamadermatol.2023.1307
https://doi.org/10.1001/jamadermatol.2023.1307
Autor:
Sam W. Lee, Stuart A. Aaronson, Anna Mandinova, César Muñoz-Fontela, Takushi Namba, Hyung-Gu Kim, Fang Tian, David Schoenfeld, Lauren Brown-Endres
PDF file - 1.6MB, Table 1. Primers used for real-time PCR analysis of NF-kB target gene expression. Fig. S1. Recombinant human TNF�� rescues CDIP apoptosis in TNF�� knockdown cells. Fig. S2. TNF�� signaling was assessed in U2OS-CDIP cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cb4a3679ebdc8e0807758937f42ee7
https://doi.org/10.1158/0008-5472.22394649
https://doi.org/10.1158/0008-5472.22394649
Autor:
Anna Mandinova, Sam W. Lee, G. Paolo Dotto, Vihren Kolev, Hyung-Gu Kim, Ivan Kehayov, Eunjeong Kwon, Jun Wang, Kevin K. Lee, Kristina Todorova, Zehua Zhu
PDF file - 557KB, Supplementary Methods Suppl. Table 1. Primers used for real time and conventional RT-PCR . Suppl. Figure S1. RhoE expression is down-regulated in skin SCC tumors. Suppl. Figure S2. Notch activation does not induce expression of memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257b68ebaf4bd564cdba8ca336054e53
https://doi.org/10.1158/0008-5472.22393817.v1
https://doi.org/10.1158/0008-5472.22393817.v1
Autor:
Jong Ho Park, Mahsa Mortaja, Heehwa Son, Marjan Azin, Jun Wang, Michael Collier, Anna Mandinova, Yevgeniy Semenov, Mari Mino-Kenudson, Shadmehr Demehri
Chronic inflammation is a major cause of cancer worldwide. Interleukin 33 (IL-33) is a critical initiator of cancer-prone chronic inflammation; however, its induction mechanism by the environmental causes of chronic inflammation is unknown. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a289eae0861c49edc797642add6561c7
https://doi.org/10.21203/rs.3.rs-2318750/v1
https://doi.org/10.21203/rs.3.rs-2318750/v1