Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Anna Malyshkina"'
Autor:
Julia Cecilia Madela-Mönchinger, Silver Anthony Wolf, Emanuel Wyler, Agnieszka Bauer, Marius Mischke, Lars Möller, Vanda Juranić Lisnić, Markus Landthaler, Anna Malyshkina, Sebastian Voigt
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cells (DC) play a crucial role in generating and maintaining antiviral immunity. While DC are implicated in the antiviral defense by inducing T cell responses, they can also become infected by Cytomegalovirus (CMV). CMV is not only highly s
Externí odkaz:
https://doaj.org/article/19f2ac9e1a884c6b86196e1013548e87
Autor:
Anna Malyshkina, Wibke Bayer, Philip Podschwadt, Lucas Otto, Zehra Karakoese, Kathrin Sutter, Kirsten Bruderek, Baoxiao Wang, Kerry J Lavender, Mario L Santiago, Pia Madeleine Leipe, Carina Elsner, Stefan Esser, Sven Brandau, Matthias Gunzer, Ulf Dittmer
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011725 (2023)
Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves as a murine model to study re
Externí odkaz:
https://doaj.org/article/a81ed88024bb4e859ce8d252a4270370
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD4+ T cells play an important role in immune responses against pathogens and cancer cells. Although their main task is to provide help to other effector immune cells, a growing number of infections and cancer entities have been described in which CD
Externí odkaz:
https://doaj.org/article/ed9e474db2f6407e8f8ee595e90f1f7b
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Friend virus (FV) is a complex of the Friend murine leukemia virus (F-MuLV) and the replication-defective, pathogenic spleen focus forming virus (SFFV). In the past, we used a fluorescently labeled F-MuLV to analyze FV target cell
Externí odkaz:
https://doaj.org/article/8c79dd3984fb49c892f8389b1e25ab31
Autor:
Philip Podschwadt, Anna Malyshkina, Sonja Windmann, Athanasios Papadamakis, Leonie Kerkmann, Dennis Lapuente, Matthias Tenbusch, Mengji Lu, Michael Schindler, Karl Sebastian Lang, Wiebke Hansen, Wibke Bayer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Retroviral envelope (Env) proteins have long been recognized to exhibit immunosuppressive properties, which affect the CD8+ T-cell response to an infection but also to immunization. Interestingly, we previously showed in the Friend murine leukemia vi
Externí odkaz:
https://doaj.org/article/f61df26f123f489f9237b43dcb2f1058
Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection
Autor:
Mara Schwerdtfeger, Julia Dickow, Yasmin Schmitz, Sandra Francois, Zehra Karakoese, Anna Malyshkina, Torben Knuschke, Ulf Dittmer, Kathrin Sutter
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Type I Interferons (IFNs), including numerous IFNα subtypes and IFNβ, are key molecules during innate and adaptive immune responses against viral infections. These cytokines exert various non-redundant biological activities, although binding to the
Externí odkaz:
https://doaj.org/article/6e632670a1494f1aa74e3e95bb636a60
Autor:
Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Gennadiy Zelinskyy, Sonja Windmann, Simone Schimmer, Annette Paschen, Hendrik Streeck, Kim J. Hasenkrug, Ulf Dittmer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract CD4+ helper T cells and cytotoxic CD8+ T cells are key players for adaptive immune responses against acute infections with retroviruses. Similar to textbook knowledge the most important function of CD4+ T cells during an acute retrovirus inf
Externí odkaz:
https://doaj.org/article/1e388d3a0c124baca7a9c26ec6d000a3
Autor:
Nadine Bongard, Vu Thuy Khanh Le-Trilling, Anna Malyshkina, Meike Rückborn, Kerstin Wohlgemuth, Ina Wensing, Sonja Windmann, Ulf Dittmer, Mirko Trilling, Wibke Bayer
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008043 (2019)
Immunization vectors based on cytomegalovirus (CMV) have attracted a lot of interest in recent years because of their high efficacy in the simian immunodeficiency virus (SIV) macaque model, which has been attributed to their ability to induce strong,
Externí odkaz:
https://doaj.org/article/7c2b05a230f14cff90dc3af77d9de32a
Diverse Immunomodulatory Effects of Individual IFNα Subtypes on Virus-Specific CD8+ T Cell Responses
Autor:
Julia Dickow, Sandra Francois, Rouven-Luca Kaiserling, Anna Malyshkina, Ingo Drexler, Astrid Maria Westendorf, Karl Sebastian Lang, Mario L. Santiago, Ulf Dittmer, Kathrin Sutter
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Clinical administration of Interferon α (IFNα) resulted in limited therapeutic success against some viral infections. Immune modulation of CD8+ T cell responses during IFNα therapy is believed to play a pivotal role in promoting viral clearance. H
Externí odkaz:
https://doaj.org/article/22174c0feaf74d6f9aa51b59a39edd3a
Autor:
Sonja Windmann, Lucas Otto, Camilla Patrizia Hrycak, Anna Malyshkina, Nadine Bongard, Paul David, Matthias Gunzer, Ulf Dittmer, Wibke Bayer
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT B cell follicles of the spleen and lymph nodes are immune privileged sites and serve as sanctuaries for infected CD4+ cells in HIV infection. It is assumed that CD8+ T cell responses promote the establishment of the reservoir, as B cell foll
Externí odkaz:
https://doaj.org/article/c3c4eee29d0d4f0e9177badd16b69523