Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna MANNO"'
Autor:
Maura FERRARI BRAVO, Fabrizio GALLO, Concetta MARCHELLO, Roberta BOICELLI, Silvia LUPI, Massimiliano ATZEI, Francesco BRUNETTI, Romina CASARETTO, Federico DAPELO, Daniela GEREVINI, Eliana LEONARDELLI, Anna MANNO, Elisabetta PERI, Paola SOAVE, Angelo TRAVERSARO, Antonio ZAMPOGNA, Roberto ZUNINO, Armando STEFANATI, Giovanni GABUTTI
Publikováno v:
Iranian Journal of Public Health, Vol 47, Iss 5 (2018)
Background: Malnutrition, a very common condition in the elderly, is known to increase their vulnerability to adverse health events. This study aimed to estimate the prevalence of malnutrition in the over 75-yr-old community-dwelling population in th
Externí odkaz:
https://doaj.org/article/0fa797d27d6f45bf96d2dc51552e8066
Autor:
Rosa Anna Manno, James P. Morrison, Aaron M. Sargeant, Ingrid D. Pardo, Brad Bolon, Robert H. Garman, Raffaella Capobianco
Publikováno v:
Toxicologic Pathology. 49:1140-1163
The use of minipigs as an alternative nonclinical species has increased in the last 20 years. The Society of Toxicologic Pathology (STP) has produced generic “best practice” recommendations for nervous system sampling in nonrodents during general
Autor:
Yuval Ramot, Yonit Tsarfati, Rosa Anna Manno, Abraham Nyska, Oron Yacoby-Zeevi, Ronit Shaltiel-Karyo, Robert R. Maronpot, Giuseppe Sacco
Publikováno v:
Toxicologic Pathology. 45:764-773
A 90-day study in Göttingen minipigs was conducted to test the local tolerability and systemic toxicity of ND0612, a novel aqueous solution of carbidopa (CD)/levodopa (LD) intended for the treatment of Parkinson’s disease by continuous subcutaneou
Autor:
Itay Perlstein, Abraham Nyska, Oron Yacobi-Zeevi, Yuval Ramot, Liat Adar, Rosa Anna Manno, Cecile Durlach, Danny Fishelovitch, Sheila Oren, Giuseppe Sacco
Publikováno v:
CNS drugs. 32(5)
Subcutaneous apomorphine is used for the treatment of Parkinson’s disease (PD); however, infusion site reactions are a common adverse event (AE), which can lead to treatment discontinuation. Apomorphine formulations that are more tolerable and conv
Autor:
J. Craig Rowlands, Abraham Nyska, Robert A. Budinsky, Greg D. Martin, Marie Lawson, Russell S. Thomas, Renee R. Hukkanen, Debra K. Layko, Rosa Anna Manno, Andrea Grassetti, Joshua A. Harrill
Publikováno v:
Journal of Applied Toxicology. 36:802-814
Sustained activation of the aryl hydrocarbon receptor (AHR) is believed to be the initial key event in AHR receptor-mediated tumorigenesis in the rat liver. The role of AHR in mediating pathological changes in the liver prior to tumor formation was i
Publikováno v:
Toxicologic Pathology. 39:700-705
The Göttingen minipig is one of the nonrodent species recommended by various regulatory authorities for safety assessment of drugs in preclinical studies. In such studies, knowledge of background pathology is critical in order to evaluate the potent
Autor:
Yuval Ramot, Rose Anna Manno, Yoshimasa Okazaki, Enrico Vezzali, Michael Krakovsky, Amir Toren, Moran Meiron, Efrat Zehavi-Goldstein, Abraham Nyska, Itschak Lamensdorf
Publikováno v:
Toxicologic Pathology. 37:667-671
We examined whether high incidence rates (18%–56%) of inflammation in the root of the aorta detected in a Balb/c mouse model for hind limb ischemia were related to the surgical procedure. Twenty mice underwent ligation of the femoral artery; incide
Publikováno v:
Journal of applied toxicology : JAT. 36(8)
Doxorubicin can cause life-threatening toxic effects in several organs, with cardiotoxicity being the major concern. Although a large number of animal models have been utilized to study doxorubicin toxicity, several restrictions limit their use. Sinc
Autor:
Joshua A, Harrill, Debra, Layko, Abraham, Nyska, Renee R, Hukkanen, Rosa Anna, Manno, Andrea, Grassetti, Marie, Lawson, Greg, Martin, Robert A, Budinsky, J Craig, Rowlands, Russell S, Thomas
Publikováno v:
Journal of applied toxicology : JAT. 36(6)
Sustained activation of the aryl hydrocarbon receptor (AHR) is believed to be the initial key event in AHR receptor-mediated tumorigenesis in the rat liver. The role of AHR in mediating pathological changes in the liver prior to tumor formation was i
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:379-380