Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Anna M.W. Taylor"'
Publikováno v:
Neurobiology of Pain, Vol 7, Iss , Pp - (2020)
Globally, it is estimated that one in five people suffer from chronic pain, with prevalence increasing with age. The pathophysiology of chronic pain encompasses complex sensory, immune, and inflammatory interactions within both the central and periph
Externí odkaz:
https://doaj.org/article/8275495c2ee544bfa7330a300098618a
Autor:
Zoë Dworsky-Fried, Simonetta Sipione, Matthew A. Churchward, Anna M.W. Taylor, Kathryn G. Todd, Gaurav Shrivastava, Noam Steinberg, Edward N. Schmidt, Fabrizio Giuliani, Qian Wang, Kamaldeep S. Dhami, Danny Galleguillos, Chris Power, Matthew S. Macauley, Gour Chand Daskhan, Asifa Zaidi
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundGangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects in the ganglioside biosynthetic pathway result in severe neurodegene
Publikováno v:
Neuropharmacology. 233:109546
Publikováno v:
Pain. 163:e49-e61
Chronic pain is a highly prevalent symptom associated with the autoimmune disorder multiple sclerosis (MS). The central nucleus of the amygdala plays a critical role in pain processing and modulation. Neuropathic pain alters nociceptive signaling in
Autor:
Sadaf Mehrabani, Haley Hrncir, Anna M.W. Taylor, Caylin I. Chadwick, Christopher J. Evans, Arthur P. Arnold
Publikováno v:
J Neurosci Res
Kappa opioid receptor (KOR) agonists produce robust analgesia with minimal abuse liability and are considered promising pharmacological agents to manage chronic pain and itch. The KOR system is also notable for robust differences between the sexes, w
Autor:
Anna M.W. Taylor, Lindsay M. Lueptow, F. Ivy Carroll, Inés Ibarra-Lecue, Tuan Trang, Joshua K. Hakimian, Kristina Komarek, Frances M. Leslie, Anne M. Andrews, Amie L. Severino, Shiwei Liu, Sarah Pickens, Caroline E. Bass, Hongyan Yang, Christopher Cook, Wendy Walwyn, Nicole E. Burma, Catherine M. Cahill, Christopher J. Evans, Lihua Xue, Mary C. Olmstead
Publikováno v:
The Journal of Neuroscience. 39:4162-4178
Pain is a multidimensional experience and negative affect, or how much the pain is “bothersome”, significantly impacts the sufferers' quality of life. It is well established that the κ opioid system contributes to depressive and dysphoric states
Publikováno v:
Mol Pharmacol
For decades the broad role of opioids in addiction, neuropsychiatric disorders, and pain states has been somewhat well established. However, in recent years, with the rise of technological advances, not only is the existing dogma being challenged, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d676126c574f1daced00bce0d01ea1
https://europepmc.org/articles/PMC7562975/
https://europepmc.org/articles/PMC7562975/
Autor:
Mochtar Pribadi, Anna M.W. Taylor, Catherine M. Cahill, Alden Y. Huang, Atefeh Ghogha, Tanya S. J. Kim, Christopher J. Evans, Q. Wang, Giovanni Coppola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010be52f7e0f7e142696cc17d85aca0e
https://doi.org/10.1002/jnr.24682/v2/response1
https://doi.org/10.1002/jnr.24682/v2/response1
Autor:
Mochtar Pribadi, Alden Y. Huang, Tanya S. J. Kim, Anna M.W. Taylor, Giovanni Coppola, Catherine M. Cahill, Atefeh Ghogha, Q. Wang, Christopher J. Evans
Publikováno v:
Journal of neuroscience researchREFERENCES. 100(1)
The actions of endogenous opioids and nociceptin/orphanin FQ are mediated by four homologous G protein-coupled receptors that constitute the opioid receptor family. However, little is known about opioid systems in cyclostomes (living jawless fish) an