Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Anna M. Vetrano"'
Autor:
Ximi K Wang, Monica Agarwal, Nataliya Parobchak, Alex Rosen, Anna M Vetrano, Aarthi Srinivasan, Bingbing Wang, Todd Rosen
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147013 (2016)
Women exposed to phthalates during pregnancy are at increased risk for delivering preterm, but the mechanism behind this relationship is unknown. Placental corticotropin-releasing hormone (CRH) and cyclooxygenase-2 (COX-2) are key mediators of partur
Externí odkaz:
https://doaj.org/article/20b9555cef24453c9e0b057b14698a1b
Autor:
Jianyao Du, Anna M. Vetrano, Kristin M. Bircsak, Lauren M. Aleksunes, Ludwik Gorczyca, Xia Wen
Publikováno v:
FEBS Lett
Low oxygen concentration, or hypoxia, is an important physiological regulator of placental function including chemical disposition. Here, we compared the ability of low oxygen tension to alter the expression of solute carriers (SLC) and ABC transport
Autor:
A M Gow, Maya Ramagopal, Pamela Ohman-Strickland, Barry Weinberger, Elizabeth Yen, Robert Laumbach, Anna M. Vetrano
Publikováno v:
Journal of Neonatal-Perinatal Medicine. 11:399-407
Background Tracheal aspirate is the conventional method to measure biomarkers of inflammation and oxidation from premature infants on mechanical ventilation at risk for bronchopulmonary dysplasia (BPD), but this method is invasive. Exhaled breath con
Autor:
Barry Weinberger, Laura Saba, Poi Yu Sofia Yuen, Lauren M. Aleksunes, Jamie E. Moscovitz, Naureen Memon, Xia Wen, Kristin M. Bircsak, Faith E. Archer, Anna M. Vetrano, Moiz Mohammed
Publikováno v:
Drug Metabolism and Disposition. 46:619-627
The breast cancer resistance protein (BCRP/ABCG2) is a maternally-facing efflux transporter that regulates the placental disposition of chemicals. Transcription factors and gene variants are important regulatory factors that influence transporter exp
Publikováno v:
Mediators of Inflammation, Vol 2011 (2011)
Neutrophil activity is prolonged in newborns, suggesting decreased exposure and/or responses to immunosuppressive modulators, such as 1,25-hydroxyvitamin D3 (1,25-vit D3). We hypothesized that 1,25-vit D3 suppresses neutrophil activation and that thi
Externí odkaz:
https://doaj.org/article/673b51e6c3684a719f7fda535aeb2934
Publikováno v:
Placenta. 55:29-36
The breast cancer resistance protein (BCRP/ABCG2) is an efflux transporter in the placental barrier. By transporting chemicals from the fetal to the maternal circulation, BCRP limits fetal exposure to a range of drugs, toxicants, and endobiotics such
Publikováno v:
Journal of Chromatography B. 1173:122656
Pyrethroid insecticides are commonly used for residential and commercial pest control in the US. Pregnant women and their fetuses are vulnerable to pesticide exposures during critical windows of neurodevelopment. Biomonitoring for exposure requires a
Autor:
Barry Weinberger, Poi Yu Sofia Yuen, Ludwik Gorczyca, Lauren M. Aleksunes, Vivek Gupta, Kristin M. Bircsak, Anna M. Vetrano
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 357:103-113
Glyburide is frequently used to treat gestational diabetes owing to its low fetal accumulation resulting from placental efflux by the breast cancer resistance protein (BCRP)/ABCG2 transporter. Here we sought to determine how exposure to the dietary p
Autor:
Thomas M. Finetti, Jeffrey Wisnoski, Christophe Guillon, Diane E. Heck, Peter Warren DeMatteo, Anna M. Vetrano, Jaya Saxena, Angela Hunter, Ned D. Heindel, Geraldine Verderone, Jeffrey D. Laskin, Robert D. Rapp, Laurie B. Joseph
Publikováno v:
Bioorg Chem
A set of 4-(R(2)-imino)-3-mercapto-5-(R(1))-4H-1,2,4-triazoles derivatives were synthesized, characterized and evaluated for their ability to inhibit nitric oxide (NO) production in PAM212 mouse keratinocytes, which led to the discovery and the subse
Autor:
Jianyao Du, Kristin M. Bircsak, Lauren M. Aleksunes, Xia Wen, Anna M. Vetrano, Ludwik Gorczyca
Publikováno v:
Placenta. 83:e114-e115