Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna M. Van Keuren"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100979- (2021)
Summary: The mitochondrial calcium uniporter, which mediates mitochondrial Ca2+ uptake, regulates key cellular functions, including intracellular Ca2+ signaling, cell-fate determination, and mitochondrial bioenergetics. Here, we describe two compleme
Externí odkaz:
https://doaj.org/article/ce787d4030db46d59014f17d1360c5dc
Autor:
Chen-Wei Tsai, Tsung-Yun Liu, Fan-Yi Chao, Yung-Chi Tu, Madison X. Rodriguez, Anna M. Van Keuren, Zhiwei Ma, John Bankston, Ming-Feng Tsai
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The mitochondrial calcium uniporter is a Ca 2+ channel that imports cytoplasmic Ca 2+ into the mitochondrial matrix to regulate cell bioenergetics, intracellular Ca 2+ signaling, and apoptosis. The uniporter contains the pore-forming MCU subunit, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0dab7206be574cb4381d353a6b6b314
https://doi.org/10.1073/pnas.2217665120
https://doi.org/10.1073/pnas.2217665120
Autor:
Joseph D. Cleveland, Amir Taslimi, Qi Liu, Anna M. Van Keuren, Mair E. A. Churchill, Chandra L. Tucker
Publikováno v:
ACS synthetic biology. 11(10)
Proteases with reprogrammed specificity for nonnative substrates are highly desired in synthetic biology and biomedicine. However, generating reprogrammed proteases that are orthogonal and highly specific for a new target has been a major challenge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382756eacb98b73cd3ee8201fc6b29a3
https://pubmed.ncbi.nlm.nih.gov/36153971
https://pubmed.ncbi.nlm.nih.gov/36153971
The mitochondrial calcium uniporter imports cytoplasmic Ca2+ into the mitochondrial matrix to regulate cell bioenergetics, Ca2+ signaling, and apoptosis. The uniporter contains the pore-forming MCU subunit, an EMRE protein that binds to MCU, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a938f8f4cbe35c18b9412334cba1530
https://doi.org/10.1101/2021.11.15.468501
https://doi.org/10.1101/2021.11.15.468501
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 4, Pp 100979-(2021)
STAR Protocols, Vol 2, Iss 4, Pp 100979-(2021)
Summary The mitochondrial calcium uniporter, which mediates mitochondrial Ca2+ uptake, regulates key cellular functions, including intracellular Ca2+ signaling, cell-fate determination, and mitochondrial bioenergetics. Here, we describe two complemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604690cca62beea7f0c627d4c217dea5
http://europepmc.org/articles/PMC8633362
http://europepmc.org/articles/PMC8633362
Autor:
Chen-Wei Tsai, Madison X. Rodriguez, Anna M. Van Keuren, Charles B. Phillips, Hannah M. Shushunov, Jessica E. Lee, Anastacia M. Garcia, Amrut V. Ambardekar, Joseph C. Cleveland, Julie A. Reisz, Catherine Proenza, Kathryn C. Chatfield, Ming-Feng Tsai
Publikováno v:
Molecular Cell. 82:3661-3676.e8
Mitochondrial Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b632d0d585f8a567f5cba32df65c46
https://doi.org/10.1016/j.molcel.2022.09.006
https://doi.org/10.1016/j.molcel.2022.09.006
Publikováno v:
Biophysical Journal. 118:174a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3be594d70497b80ef7acd2d4d1e13b20
https://doi.org/10.1016/j.bpj.2019.11.1061
https://doi.org/10.1016/j.bpj.2019.11.1061
Autor:
Enrique Balderas, Madison X. Rodriguez, Dipayan Chaudhuri, Anna M. Van Keuren, Ming-Feng Tsai, Chen-Wei Tsai
Publikováno v:
Cell reports
SUMMARY The mitochondrial calcium uniporter is a multi-subunit Ca2+-activated Ca2+ channel, made up of the pore-forming MCU protein, a metazoan-specific EMRE subunit, and MICU1/MICU2, which mediate Ca2+ activation. It has been established that metazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e275b3e05164b7b3b9871142bab12fe
http://europepmc.org/articles/PMC7764451
http://europepmc.org/articles/PMC7764451