Histamine Ingestion by Anopheles stephensi Alters Important Vector Transmission Behaviors and Infection Success with Diverse Plasmodium Species

Autor: Anna M. Rodriguez, Malayna G. Hambly, Sandeep Jandu, Raquel Simão-Gurge, Casey Lowder, Edwin E. Lewis, Jeffrey A. Riffell, Shirley Luckhart

Publikováno v: Biomolecules, Vol 11, Iss 5, p 719 (2021)

An estimated 229 million people worldwide were impacted by malaria in 2019. The vectors of malaria parasites (Plasmodium spp.) are Anopheles mosquitoes, making their behavior, infection success, and ultimately transmission of great importance. Indivi

Externí odkaz: https://doaj.org/article/4e17e71cdb79412ebb09f06ada0bcb2e

Manipulation of pantothenate kinase in Anopheles stephensi suppresses pantothenate levels with minimal impacts on mosquito fitness

Autor: Neha Thakre, Raquel M. Simão Gurge, Jun Isoe, Heather Kivi, Jessica Strickland, Lillian R. Delacruz, Anna M. Rodriguez, Reagan Haney, Rohollah Sadeghi, Teresa Joy, Minhao Chen, Shirley Luckhart, Michael A. Riehle

Publikováno v: Insect biochemistry and molecular biology. 149

Pantothenate (Pan) is an essential nutrient required by both the mosquito vector and malaria parasite. We previously demonstrated that increasing pantothenate kinase (PanK) activity and co-enzyme A (CoA) biosynthesis led to significantly decreased pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8eea740b566e14325dc6388f4dad01
https://pubmed.ncbi.nlm.nih.gov/36087890

Activation of Anopheles stephensi Pantothenate Kinase and Coenzyme A Biosynthesis Reduces Infection with Diverse Plasmodium Species in the Mosquito Host

Autor: Anna M. Rodriguez, Shirley Luckhart, Jun Isoe, Brandi K. Torrevillas, Neha Thakre, Raquel M. Simão-Gurge, Michael A. Riehle, Jessica Strickland, Lillian R. Delacruz

Publikováno v: Biomolecules
Volume 11
Issue 6
Biomolecules, Vol 11, Iss 807, p 807 (2021)

Malaria parasites require pantothenate from both human and mosquito hosts to synthesize coenzyme A (CoA). Specifically, mosquito-stage parasites cannot synthesize pantothenate de novo or take up preformed CoA from the mosquito host, making it essenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c88b66551d7e06261b9f4bbeafe2b7
http://europepmc.org/articles/PMC8228300

Biominerals formed by DNA and calcium oxalate or hydroxyapatite: a comparative study

Autor: Pau Turon, Carlos Aleman, Juana Del Valle Mendoza, Guillem Revilla-López, Luis J. Del Valle, Anna M. Rodriguez-Rivero, Jordi Puiggali

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)

Biominerals formed by DNA and calcium oxalate (CaOx) or hydroxyapatite (HAp), the most important and stable phase of calcium phosphate) have been examined and compared using a synergistic combination of computer simulation and experimental studies. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90305d41ca4fd843f8a1d28c7b75278
https://hdl.handle.net/2117/172986

Models for the directed evolution of bacterial allelopathy: bacteriophage lysins

Autor: Anna M. Rodriguez, Stephen M. Krone, James J. Bull, Cameron J. Crandall

Publikováno v: PeerJ
PeerJ, Vol 3, p e879 (2015)

Microbes produce a variety of compounds that are used to kill or suppress other species. Traditional antibiotics have their origins in these natural products, as do many types of compounds being pursued today in the quest for new antibacterial drugs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026ec6b1a69b7e41d0158676090e4edc
https://doi.org/10.7717/peerj.879