Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anna M. Quaglia"'
Autor:
Cheryl T. Hewkin, Alfredo Cugola, Paola Gastaldi, Romano Di Fabio, Nadia Conti, Fabrizio Micheli, Anna M. Quaglia
Publikováno v:
Archiv der Pharmazie. 332:55-58
A novel series of 3-carbamoylethynyl-2-carboxyindoles, antagonists acting at the strychnine-insensitive glycine binding site associated with the NMDA receptor, has been synthesised. This new versatile approach involves the introduction of a 2-chloroe
Autor:
Paola Gastaldi, Giovanni Gaviraghi, Alessandra Orlandi, Ornella Curcuruto, Aldo Feriani, Frank van Amsterdam, Carla Marchioro, Romano Di Fabio, Alfonso Pozzan, Alfredo Cugola, Anna M. Quaglia, Angelo Reggiani, Anna Maria Capelli, Fabrizio Micheli
Publikováno v:
Archiv der Pharmazie. 332:73-80
A novel series of indole-2-carboxylate analogues of GV 150526 (1) in which the terminal phenyl ring belonging to the side chain present in the position C-3 has been replaced with a bridged cycloalkyl group was synthesized and evaluated for its pharma
Autor:
Luciana Rossi, A. Feriani, Fabrizio Micheli, Anna M. Quaglia, Anna-Maria Capelli, David G. Trist, Paola Gastaldi, Angelo Reggiani, Alfredo Cugola, E. Ratti, Daniele Donati, Angelo Pecunioso, Manolo Mugnaini, Cheryl T. Hewkin, R. Di Fabio, Nadia Conti, Giovanna Tedesco, Andrea Missio, Giovanni Gaviraghi
Publikováno v:
Journal of Medicinal Chemistry. 40:841-850
A series of indole-2-carboxylates bearing suitable chains at the C-3 position of the indole nucleus was synthesized and evaluated in terms of in vitro affinity using [3H]glycine binding assay and in vivo potency by inhibition of convulsions induced b
Autor:
Paola Gastaldi, Anna M. Quaglia, Nadia Conti, Alfredo Cugola, Romano Di Fabio, Fabrizio Micheli, Cheryl T. Hewkin
Publikováno v:
ChemInform. 30
A novel series of 3-carbamoylethynyl-2-carboxyindoles, antagonists acting at the strychnine-insensitive glycine binding site associated with the NMDA receptor, has been synthesised. This new versatile approach involves the introduction of a 2-chloroe