Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna M. Ogloblina"'
Autor:
Roman G. Zenkov, Kirill I. Kirsanov, Anna M. Ogloblina, Olga A. Vlasova, Denis S. Naberezhnov, Natalia Y. Karpechenko, Timur I. Fetisov, Ekaterina A. Lesovaya, Gennady A. Belitsky, Nina G. Dolinnaya, Marianna G. Yakubovskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9209 (2022)
Guanine-rich DNA sequences tending to adopt noncanonical G-quadruplex (G4) structures are over-represented in promoter regions of oncogenes. Ligands recognizing G4 were shown to stabilize these DNA structures and drive their formation regulating expr
Externí odkaz:
https://doaj.org/article/05a632071b7f4dbd854e17254fbf3481
Autor:
Anzhela V. Pavlova, Mayya V. Monakhova, Anna M. Ogloblina, Natalia A. Andreeva, Gennady Yu. Laptev, Vladimir I. Polshakov, Elizaveta S. Gromova, Maria I. Zvereva, Marianna G. Yakubovskaya, Tatiana S. Oretskaya, Elena A. Kubareva, Nina G. Dolinnaya
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8773 (2020)
DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact o
Externí odkaz:
https://doaj.org/article/0fc4c203ba9641169340eb92738c5065
Autor:
Anna M. Ogloblina, Nunzia Iaccarino, Domenica Capasso, Sonia Di Gaetano, Emanuele U. Garzarella, Nina G. Dolinnaya, Marianna G. Yakubovskaya, Bruno Pagano, Jussara Amato, Antonio Randazzo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7781 (2020)
Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are known to bind to nucleolin protein, resulting in the inhibition of nucleolin-mediated phenomen
Externí odkaz:
https://doaj.org/article/81342a22414d4cb69d2c79a1a18e69f5
Autor:
Natalia A. Andreeva, M. V. Monakhova, Marianna G. Yakubovskaya, Elena A. Kubareva, Maria I. Zvereva, Gennady Yu. Laptev, Nina G. Dolinnaya, Anna M. Ogloblina, Tatiana S. Oretskaya, Vladimir I. Polshakov, Elizaveta S. Gromova, Anzhela V. Pavlova
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8773, p 8773 (2020)
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8773, p 8773 (2020)
DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact o
Autor:
Emanuele Ugo Garzarella, Sonia Di Gaetano, Nunzia Iaccarino, Domenica Capasso, Anna M. Ogloblina, Marianna G. Yakubovskaya, Bruno Pagano, Nina G. Dolinnaya, Jussara Amato, Antonio Randazzo
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7781, p 7781 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7781, p 7781 (2020)
Volume 21
Issue 20
Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are known to bind to nucleolin protein, resulting in the inhibition of nucleolin-mediated phenomen
Autor:
Gennady A. Belitsky, Nina G. Dolinnaya, Svetlana E. Semina, Alexandra N. Khristich, Anna M. Ogloblina, Natalia Y. Karpechenko, Marianna G. Yakubovskaya
Publikováno v:
Biochimie. 145:163-173
We selected and investigated nine G-quadruplex (G4)-forming aptamers originally designed against different proteins involved in the regulation of cellular proliferation (STAT3, nucleolin, TOP1, SP1, VEGF, and SHP-2) and considered to be potential ant
Autor:
Marianna G. Yakubovskaya, Anna M. Ogloblina, Valeria A. Bannikova, Nina G. Dolinnaya, A. N. Khristich, Tatiana S. Oretskaya
Publikováno v:
Biochemistry (Moscow). 80:1026-1038
Using UV and CD spectroscopy, we studied the thermodynamic stability and folding topology of G-quadruplexes (G4), formed by G-rich fragments in human microsatellites that differ in the number of guanosines within the repeating unit. The oligonucleoti
Autor:
Boris P. Belotserkovskii, Nina G. Dolinnaya, Sergei M. Mirkin, Marianna G. Yakubovskaya, Philip C. Hanawalt, Anna M. Ogloblina, Shristi Pandey
Publikováno v:
Nucleic Acids Research
DNA sequences that can form unusual secondary structures are implicated in regulating gene expression and causing genomic instability. H-palindromes are an important class of such DNA sequences that can form an intramolecular triplex structure, H-DNA