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pro vyhledávání: '"Anna M. Mattson"'
Autor:
Elizabeth W. Bradley, Anna M. Mattson, Merry Jo Oursler, David H. H. Molstad, Jennifer J. Westendorf, Margaret A. Meyer, Dana L. Begun
Publikováno v:
J Biol Chem
Enhanced osteoclast-mediated bone resorption and diminished formation may promote bone loss. Pleckstrin homology (PH) domain and leucine-rich repeat protein phosphatase 1 (Phlpp1) regulates protein kinase C (PKC) and other proteins in the control of
Autor:
Anna M. Mattson, Dana L. Begun, Jennifer J. Westendorf, David H. H. Molstad, Elizabeth W. Bradley
Publikováno v:
J Biol Chem
Hdac3 is a lysine deacetylase that removes acetyl groups from histones and additional proteins. Although Hdac3 functions within mesenchymal lineage skeletal cells are defined, little is known about Hdac3 activities in bone-resorbing osteoclasts. In t
Autor:
David H. H. Molstad, Ian M. Lorang, Clara M. Castillejo Becerra, Anna M. Mattson, Elizabeth W. Bradley, Jennifer J. Westendorf
Publikováno v:
Journal of Cellular Biochemistry. 119:7470-7478
The protein phosphatase Phlpp1 is an essential enzyme for proper chondrocyte function. Altered Phlpp1 levels are associated with cancer and degenerative diseases such as osteoarthritis. While much is known about the post-transcriptional mechanisms co