Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anna M. Hitz"'
Autor:
Jonathan C. Cruz, Nicole Ozerova, Richard E. Middleton, Joey L. Methot, Sujal V. Deshmukh, Christopher Hamblett, Andreas Harsch, Anna M. Hitz, Judith C. Fleming, Naim Nazef, Bethany Hughes, Melissa Chenard, Astrid M. Kral, David L. Sloman, Thomas A. Miller, William K. Dahlberg, J. Paul Secrist, Matthew G. Stanton, Ralph T. Mosley, Hongmei Wang, Dawn M. Mampreian, Alex A. Szewczak
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(19)
This communication highlights the development of a nicotinamide series of histone deacetylase inhibitors within the benzamide structural class. Extensive exploration around the nicotinamide core led to the discovery of a class I selective HDAC inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa399415c2ed87e3206d1c0265918a5
https://pubmed.ncbi.nlm.nih.gov/17761416
https://pubmed.ncbi.nlm.nih.gov/17761416
Autor:
N H Georgopapadakou, Anna M. Hitz
Publikováno v:
FEBS letters. 391(3)
Microsomal and soluble peptidases from bovine liver and pig brain hydrolyze the farnesylated, Ras-based CAAX peptide [3H]Ac-fCVIM-OH. However, they differ in their sensitivity to substrate-based inhibitors, sulfhydryl and chelating agents, pH and ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6049978decfbc860f2974ef029737b5
https://pubmed.ncbi.nlm.nih.gov/8764996
https://pubmed.ncbi.nlm.nih.gov/8764996