Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Anna M. Gumpert"'
Autor:
Xian‐Liang Tang, Shunichi Nakamura, Qianhong Li, Marcin Wysoczynski, Anna M. Gumpert, Wen‐Jian Wu, Greg Hunt, Heather Stowers, Qinghui Ou, Roberto Bolli
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 4 (2018)
BackgroundWe have recently found that 3 repeated doses (12×106 each) of c‐kitPOS cardiac progenitor cells (CPCs) were markedly more effective than a single dose of 12×106 cells in alleviating postinfarction left ventricular dysfunction and remode
Externí odkaz:
https://doaj.org/article/b52d973ff2d54bae9cb4a64b9b3efc06
Autor:
Sujith Dassanayaka, Kenneth R Brittian, Bethany W Long, Lauren A Higgins, James A Bradley, Timothy N Audam, Andrea Jurkovic, Anna M Gumpert, Linda T Harrison, István Hartyánszky, Péter Perge, Béla Merkely, Tamás Radovits, John A Hanover, Steven P Jones
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242250 (2020)
RationaleThe beta-O-linkage of N-acetylglucosamine (i.e., O-GlcNAc) to proteins is a pro-adaptive response to cellular insults. To this end, increased protein O-GlcNAcylation improves short-term survival of cardiomyocytes subjected to acute injury. T
Externí odkaz:
https://doaj.org/article/0bd4b5220506470fb0e879d5febfd118
Autor:
Alex Tomlin, Roberto Bolli, Xiaoping Zhu, Anna M. Gumpert, Qianhong Li, Jan Slezak, Yiru Guo, Arunpreet Kahlon, Yibing Nong
Publikováno v:
Stem Cell Rev Rep
Repeated doses of c-kit(+) cardiac progenitor cells (CPCs) are superior to a single dose in improving LV function in rats with old myocardial infarction (MI). However, this concept needs testing in different species to determine whether it is general
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df119534f018b3ce3f7733e983d8eef
https://doi.org/10.1007/s12015-020-10063-0
https://doi.org/10.1007/s12015-020-10063-0
Autor:
Xian-Liang Tang, Yan Li, Marcin Wysoczynski, Roberto Bolli, Anna M. Gumpert, Wen-Jian Wu, Hong Li, Heather Stowers
Publikováno v:
Mol Cell Biochem
Mounting evidence shows that cell therapy provides therapeutic benefits in experimental and clinical settings of chronic heart failure. However, direct cardiac delivery of cells via transendocardial injection is logistically complex, expensive, entai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84972e10416676e8d25c6de08809217
https://pubmed.ncbi.nlm.nih.gov/34783963
https://pubmed.ncbi.nlm.nih.gov/34783963
Autor:
Alex Tomlin, Roberto Bolli, Xiaoping Zhu, Yibing Nong, Qianhong Li, Anna M. Gumpert, Yiru Guo
Publikováno v:
Molecular and cellular biochemistry. 476(11)
Intramyocardial injection of synthetic microRNAs (miRs) has recently been reported to be beneficial after myocardial infarction (MI). We conducted a randomized blinded study to evaluate the efficacy and reproducibility of this strategy in a mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d9725126f94313c99bfa06965d2fe9
https://pubmed.ncbi.nlm.nih.gov/34287784
https://pubmed.ncbi.nlm.nih.gov/34287784
Autor:
Yiru Guo, Yibing Nong, Steven P. Jones, Andrea Jurkovic, Xiaoping Zhu, Daniel W. Riggs, Marcin Wysoczynski, Tyler Weirick, Anna M. Gumpert, Alex Tomlin, Hong Li, Kenneth R. Brittian, Yi Wei Zheng, Shizuka Uchida, Bethany W. Long, Timothy N. Audam
Publikováno v:
Am J Physiol Heart Circ Physiol
Although cell therapy-mediated cardiac repair offers promise for treatment/management of heart failure, lack of fundamental understanding of how cell therapy works limits its translational potential. In particular, whether reparative cells from faili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484d75a198dfbb9fa8a16f2dca10e305
https://pubmed.ncbi.nlm.nih.gov/32442025
https://pubmed.ncbi.nlm.nih.gov/32442025
Autor:
John A. Hanover, Linda T. Harrison, Timothy N. Audam, James Bradley, Sujith Dassanayaka, Anna M. Gumpert, Bethany W. Long, Béla Merkely, Steven P. Jones, Andrea Jurkovic, István Hartyánszky, Lauren A. Higgins, Péter Perge, Kenneth R. Brittian, Tamás Radovits
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242250 (2020)
PLoS ONE, Vol 15, Iss 11, p e0242250 (2020)
Rationale The beta-O-linkage of N-acetylglucosamine (i.e., O-GlcNAc) to proteins is a pro-adaptive response to cellular insults. To this end, increased protein O-GlcNAcylation improves short-term survival of cardiomyocytes subjected to acute injury.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25facdef66f13f2ba81b8f1aa37b1780
https://pubmed.ncbi.nlm.nih.gov/33253217
https://pubmed.ncbi.nlm.nih.gov/33253217
The A-to-I RNA Editing Enzyme Adar1 Is Essential for Normal Embryonic Cardiac Growth and Development
Autor:
Anna M. Gumpert, Annalara G. Fischer, Marcin Wysoczynski, Giuseppe Militello, Ghazal Sadri, Joseph B. Moore, Shizuka Uchida, Thomas Braun, Tyler Weirick
Publikováno v:
Circ Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42f2f7da3790e43232c1ad7c2772ae3
https://europepmc.org/articles/PMC7415551/
https://europepmc.org/articles/PMC7415551/
Autor:
Joseph B. Moore, Gregory N. Hunt, Anna M. Gumpert, Marcin Wysoczynski, Yibing Nong, Qianhong Li, Xiaoping Zhu, Michael Book, Alex Tomlin, Wen-Jian Wu, Xian-Liang Tang, Senthilkumar K. Muthusamy, Abdur Rahman Khan, Roberto Bolli, Hong Li, Yiru Guo, Marjan Nasr
Publikováno v:
Journal of the American College of Cardiology. 69:1824-1838
Background The authors previously reported that the c-kit–positive (c-kitPOS) cells isolated from slowly adhering (SA) but not from rapidly adhering (RA) fractions of cardiac mesenchymal cells (CMCs) are effective in preserving left ventricular (LV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad680a8c76e37cbc2bc2938f5991a9bd
https://doi.org/10.1016/j.jacc.2017.01.048
https://doi.org/10.1016/j.jacc.2017.01.048
Autor:
Mitali G. Chitre, Bethany W. Long, Linda T. Harrison, Lauren A. Higgins, Giuseppe Militello, Shizuka Uchida, Daniel W. Riggs, Anna M. Gumpert, Kenneth R. Brittian, Steven P. Jones, Timothy N. Audam, Andrea Jurkovic, Senthilkumar K. Muthusamy, Sujith Dassanayaka
Publikováno v:
Basic Res Cardiol
Several post-translational modifications figure prominently in ventricular remodeling. The beta-O-linkage of N-acetylglucosamine (O-GlcNAc) to proteins has emerged as an important signal in the cardiovascular system. Although there are limited insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b6917eb8ececbdd99bd872147fc973
https://doi.org/10.1007/s00395-019-0737-y
https://doi.org/10.1007/s00395-019-0737-y