Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna M. Barbeau"'
Autor:
Christopher Chidley, Alicia M. Darnell, Benjamin L. Gaudio, Evan C. Lien, Anna M. Barbeau, Matthew G. Vander Heiden, Peter K. Sorger
Blocking the import of nutrients essential for cancer cell proliferation represents a therapeutic opportunity, but it is unclear which transporters to target. Here, we report a CRISPRi/a screening platform to systematically interrogate the contributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6618061bbd101132cdf4a515ab80e86
https://doi.org/10.1101/2023.01.26.525375
https://doi.org/10.1101/2023.01.26.525375
Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors
Autor:
Rupsa Datta, Sharanya Sivanand, Allison N. Lau, Logan V. Florek, Anna M. Barbeau, Jeffrey Wyckoff, Melissa C. Skala, Matthew G. Vander Heiden
Publikováno v:
Science Advances
Access to electron acceptors supports oxidized biomass synthesis and can be limiting for cancer cell proliferation, but how cancer cells overcome this limitation in tumors is incompletely understood. Nontransformed cells in tumors can help cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8323c88e2d05b4156420cf7999ebf594
https://doi.org/10.1126/sciadv.abg6383
https://doi.org/10.1126/sciadv.abg6383
Autor:
Klaudia Szymczak, Margery G. H. Pelletier, Krishnakumar Malu, Anna M. Barbeau, Richard M. Giadone, Seda C. Babroudi, Peter C. W. Gaines
Publikováno v:
ImmunoHorizons. 6(1)
Neutrophils mediate critical innate immune responses by migrating to sites of infection or inflammation, phagocytosing microorganisms, and releasing an arsenal of antimicrobial agents, including reactive oxygen species. These functions are shared by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9602f10a26f46d4c7a99b11e33c311e0
https://pubmed.ncbi.nlm.nih.gov/35039433
https://pubmed.ncbi.nlm.nih.gov/35039433
Autor:
Paul J. Tesar, Robert T. Karl, Drew J. Adams, Tyler E. Miller, Ranjan Dutta, Gursimran Dhillon, Olivia Corradin, An T. Hoang, Parker A. Hall, Bruna R. Lima, Sagar Nisraiyya, Alexey Kozlenkov, Mayur Madhavan, Anna M. Barbeau, Christina Volsko, Cynthia F. Bartels, Peter C. Scacheri, Stella Dracheva, Fadi J. Najm, Kathryn E.A. Hazel, Daniel C. Factor, Zachary S. Nevin
Publikováno v:
SSRN Electronic Journal.
Multiple sclerosis (MS) is an autoimmune disease characterized by attack on oligodendrocytes within the central nervous system (CNS). Despite widespread use of immunomodulatory therapies, patients face progressive disability due to failure of myelin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b3ac34c8fa5479cd091082af08c3a91
https://doi.org/10.2139/ssrn.3453290
https://doi.org/10.2139/ssrn.3453290
Autor:
Gursimran Dhillon, Cynthia F. Bartels, Ranjan Dutta, Peter C. Scacheri, Stella Dracheva, Lucille R. Hu, Kevin C. Allan, Fadi J. Najm, Michael D. Gallagher, Anna M. Barbeau, Christina Volsko, Mayur Madhavan, Parker A. Hall, Bruna R. Lima, Kathryn E.A. Hazel, Daniel C. Factor, William Phu, Alexandra G. Sibert, Yanwei Song, Robert T. Karl, Olivia Corradin, An T. Hoang, Drew J. Adams, Sagar Nisraiyya, Alexey Kozlenkov, Zachary S. Nevin, Tyler E. Miller, Paul J. Tesar
Publikováno v:
Cell
Summary Multiple sclerosis (MS) is an autoimmune disease characterized by attack on oligodendrocytes within the central nervous system (CNS). Despite widespread use of immunomodulatory therapies, patients may still face progressive disability because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb01bb74e36636f4940a07aaaca35da
https://doi.org/10.1016/j.cell.2020.03.002
https://doi.org/10.1016/j.cell.2020.03.002
Autor:
Kevin S. O’Fallon, Peter Gaines, Gianna N. Prata, Anna M. Barbeau, Margery G.H. Pelletier, Klaudia Szymczak
Neutrophils and macrophages differentiate from common myeloid progenitors in the bone marrow, where they undergo nuclear morphologic changes during maturation. During this process, both cell types acquire critical innate immune functions that include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6bf339470e8fe7236787c9c52d67bb
https://europepmc.org/articles/PMC5205552/
https://europepmc.org/articles/PMC5205552/
Autor:
Margery G.H. Pelletier, Klaudia Szymczak, Anna M. Barbeau, Erin J. Bishop, Benjamin B. Johnson, Andrew J. Lee, Kevin S. O’Fallon, Peter Gaines
Publikováno v:
The Journal of Immunology. 200:46.20-46.20
Ingestion of tart cherry extract (TCE), a rich source of polyphenolic anti-oxidant/anti-inflammatory compounds, improves skeletal muscle (SM) recovery following exercise-induced muscle damage. This response may be due in part to attenuated oxidative/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0b180b602334993330db69b5606b2f
https://doi.org/10.4049/jimmunol.200.supp.46.20
https://doi.org/10.4049/jimmunol.200.supp.46.20
Autor:
Kevin S. O’Fallon, Gianna N. Prata, Klaudia Szymczak, Peter Gaines, Anna M. Barbeau, Krishnakumar Malu, Margery G.H. Pelletier
Publikováno v:
Blood. 128:407-407
Neutrophils differentiate from common myeloid progenitors in the bone marrow where they form uniquely lobulated nuclei while acquiring multiple functions critical to their innate immune responses. We are investigating the roles of nuclear envelope (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97ac23d73b8de0401ac8acd1ca5d9a0
https://doi.org/10.1182/blood.v128.22.407.407
https://doi.org/10.1182/blood.v128.22.407.407