In uveal melanoma, angiopoietin-2 but not angiopoietin-1 is increased in high-risk tumors, providing a potential druggable target

Autor: Martine J. Jager, Pieter A. van der Velden, Annemijn P A Wierenga, Gregorius P M Luyten, Robert M. Verdijk, Anna M W Ten Voorde, Rogier J. Nell

Publikováno v: Cancers
Cancers, 13(16). MDPI
Cancers, 13(16):3986. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, Vol 13, Iss 3986, p 3986 (2021)
Volume 13
Issue 16

Uveal melanoma (UM) metastasize haematogeneously, and tumor blood vessel density is an important prognostic factor. We hypothesized that proangiogenic factors such as angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2), two targetable cytokines, might

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1438639973deff2b26e21d68e6ce0aa
https://pure.eur.nl/en/publications/333d859f-0923-4306-862c-2832843ccbea