Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anna M Sigmund"'
Autor:
Anna M. Sigmund, Markus Winkler, Sophia Engelmayer, Daniela Kugelmann, Desalegn T. Egu, Letyfee S. Steinert, Michael Fuchs, Matthias Hiermair, Mariya Y. Radeva, Franziska C. Bayerbach, Elisabeth Butz, Stefan Kotschi, Christoph Hudemann, Michael Hertl, Sunil Yeruva, Enno Schmidt, Amir S. Yazdi, Kamran Ghoreschi, Franziska Vielmuth, Jens Waschke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Pemphigus vulgaris is a life-threatening blistering skin disease caused by autoantibodies which destabilize cell adhesion of keratinocytes. The phosphodiesterase 4 inhibitor apremilast prevents skin blistering by stabilizing the keratin filament anch
Externí odkaz:
https://doaj.org/article/a933bd3a4505443a83704c045d6c6602
Autor:
Daniela Kugelmann, Maresa Anders, Anna M. Sigmund, Desalegn T. Egu, Ramona A. Eichkorn, Amir S. Yazdi, Miklós Sárdy, Michael Hertl, Dario Didona, Takashi Hashimoto, Jens Waschke
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The severe autoimmune blistering disease Pemphigus vulgaris (PV) is mainly caused by autoantibodies (IgG) against desmoglein (Dsg) 3 and Dsg1. The mechanisms leading to the development of blisters are not fully understood, but intracellular signaling
Externí odkaz:
https://doaj.org/article/bf9ecf11ae6e48e982490804fb4a2c1c
Autor:
Anna M. Sigmund, Markus Winkler, Sophia Engelmayer, Daniela Kugelmann, Desalegn T. Egu, Letyfee S. Steinert, Michael Fuchs, Matthias Hiermaier, Mariya Y. Radeva, Franziska C. Bayerbach, Elisabeth Butz, Stefan Kotschi, Christoph Hudemann, Michael Hertl, Sunil Yeruva, Enno Schmidt, Amir S. Yazdi, Kamran Ghoreschi, Franziska Vielmuth, Jens Waschke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1bce74d7b5764a4e8f7f6dbd99a47975
Autor:
Anna M. Sigmund, Letyfee S. Steinert, Desalegn T. Egu, Franziska C. Bayerbach, Jens Waschke, Franziska Vielmuth
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulate
Externí odkaz:
https://doaj.org/article/6d09b3a1b12a4622a35e71f18f709c87
Publikováno v:
Acta Physiologica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a789e18b0c458fc6bc9b0f3ebe9e2d
https://doi.org/10.1111/apha.14006
https://doi.org/10.1111/apha.14006
Autor:
Anna M. Sigmund, Markus Winkler, Sophia Engelmayer, Desalegn T. Egu, Daniela Kugelmann, Mariya Y. Radeva, Franziska C. Bayerbach, Stefan Kotschi, Sunil Yeruva, Enno Schmidt, Amir S. Yazdi, Kamran Ghoreschi, Franziska Vielmuth, Jens Waschke
Pemphigus vulgaris (PV) is a life-threatening blistering skin disease caused by autoantibodies (PV-IgG) destabilizing desmosomal adhesion. Current therapies focus on suppression of autoantibody formation and thus treatments directly stabilizing kerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d8015369a2d55ae7e9ed167ab567718
https://doi.org/10.1101/2022.02.07.478931
https://doi.org/10.1101/2022.02.07.478931
Autor:
Daniela, Kugelmann, Maresa, Anders, Anna M, Sigmund, Desalegn T, Egu, Ramona A, Eichkorn, Amir S, Yazdi, Miklós, Sárdy, Michael, Hertl, Dario, Didona, Takashi, Hashimoto, Jens, Waschke
Publikováno v:
Frontiers in immunology 13, 884248 (2022). doi:10.3389/fimmu.2022.884248
Frontiers in immunology 13, 884248 (2022). doi:10.3389/fimmu.2022.884248
Published by Frontiers Media, Lausanne
Published by Frontiers Media, Lausanne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa5f67290256e6bf4f0675e5b9e898d
Publikováno v:
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 241
Pemphigus vulgaris (PV) is a severe autoimmune blistering skin disease caused primarily by autoantibodies (PV-IgG) against the desmosomal cadherins desmoglein (Dsg) 1 and Dsg 3. Pemphigus is a model disease to study desmosome regulation because patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cadb92890b8c7f27326085c01ceedafb
https://pubmed.ncbi.nlm.nih.gov/35131450
https://pubmed.ncbi.nlm.nih.gov/35131450
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 241:151904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80a61a0a495521c7c5b77fc6b394ed9
https://doi.org/10.1016/j.aanat.2022.151904
https://doi.org/10.1016/j.aanat.2022.151904
Autor:
Zhijian J. Chen, Anna M Sigmund, Holger Heine, Carsten J. Kirschning, André Jenckel, Marion Kauth, Stephanie Brand, Karina Stein
Background Bacterial cowshed isolates are allergy protective in mice; however, the underlying mechanisms are largely unknown. We examined the ability of Lactococcus lactis G121 to prevent allergic inflammatory reactions. Objective We sought to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5864263cc74474d7190e6a73fd097d16
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84996570097
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84996570097