Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna M Schulz"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The presence of atypical cytoskeletal dynamics, structures, and associated morphologies is a common theme uniting numerous diseases and developmental disorders. In particular, cytoskeletal dysregulation is a common cellular feature of Alzheimer’s d
Externí odkaz:
https://doaj.org/article/5f78b52144a04b65bfc68b24b799b544
Autor:
Stefanie Scherer, Susanne G. Oberle, Kristiyan Kanev, Ann-Katrin Gerullis, Ming Wu, Gustavo P. de Almeida, Daniel J. Puleston, Francesc Baixauli, Lilian Aly, Alessandro Greco, Tamar Nizharadze, Nils B. Becker, Madlaina v. Hoesslin, Lara V. Donhauser, Jacqueline Berner, Talyn Chu, Hayley A. McNamara, Zeynep Esencan, Patrick Roelli, Christine Wurmser, Ingo Kleiter, Maria J. G. T. Vehreschild, Christoph A. Mayer, Percy Knolle, Martin Klingenspor, Valeria Fumagalli, Matteo Iannacone, Martin Prlic, Thomas Korn, Erika L. Pearce, Thomas Höfer, Anna M. Schulz, Dietmar Zehn
Publikováno v:
Nature Immunology
Blocking pyrimidine de novo synthesis by inhibiting dihydroorotate dehydrogenase is used to treat autoimmunity and prevent expansion of rapidly dividing cell populations including activated T cells. Here we show memory T cell precursors are resistant
Publikováno v:
Nature Immunology. 24:213-215
Autor:
Sourav Roy, Charles E. Booth, Alexandra D. Powell-Pierce, Anna M. Schulz, Jon T. Skare, Brandon L. Garcia
Borrelial pathogens are vector-borne etiological agents of Lyme disease, relapsing fever, andBorrelia miyamotoidisease. These spirochetes each encode several surface-localized lipoproteins that bind to components of the human complement system. BBK32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ce14c877e5491443455394bd97f7cfd
https://doi.org/10.1101/2023.03.01.530473
https://doi.org/10.1101/2023.03.01.530473
Publikováno v:
Bioconjugate chemistry.
Protein kinase A (PKA) is a biologically important enzyme for cell regulation, often referred to as the "central kinase". An immobilized PKA that retains substrate specificity and activity would be a useful tool for laboratory scientists, enabling ta
Autor:
Anna M, Schulz, Dietmar, Zehn
Publikováno v:
Immunology and cell biologyREFERENCES. 100(2)
A recent study by Gabriel et al. provides novel insight into the metabolic pathways that contribute to T cell differentiation in chronic infection. The researchers discovered that metabolic plasticity and the function of exhausted T cells is regulate
Autor:
Markus Tölle, Cornelia Henkel, Jaqueline Herrmann, Christoph Daniel, Milen Babic, Mengdi Xia, Anna M. Schulz, Kerstin Amann, Markus van der Giet, Mirjam Schuchardt
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 100(9)
Calcification and chronic inflammation of the vascular wall is a high-risk factor for cardiovascular mortality, especially in patients with chronic uremia. For the reduction or prevention of rapid disease progression, no specific treatment options ar
Autor:
Cole M. Haynes, Adolfo Garcia-Ocaña, Misung Kim, Dirk Homann, Bennett Davenport, Mark A. Herman, Liora S. Katz, Jerry E. Chipuk, Lucy Li, Anna M Schulz, Donald K. Scott, Lee B Honig, Anil Kumar
Publikováno v:
Diabetes
Patients with both major forms of diabetes would benefit from therapies that increase β-cell mass. Glucose, a natural mitogen, drives adaptive expansion of β-cell mass by promoting β-cell proliferation. We previously demonstrated that a carbohydra
Autor:
Mark W. Pellegrino, Yi-Fan Lin, Anna M. Schulz, Cole M. Haynes, Nadine Rosin, Christopher J. Fiorese
Publikováno v:
Current Biology. 26:2037-2043
Mitochondrial dysfunction is pervasive in human pathologies such as neurodegeneration, diabetes, cancer, and pathogen infections as well as during normal aging. Cells sense and respond to mitochondrial dysfunction by activating a protective transcrip
Autor:
Susanne Stutte, Axel Imhof, Diana Dudziak, Sebastian Hogl, Thomas Brocker, Cord Brakebusch, Nancy Luckashenak, Céline Leroy, Ignasi Forné, Anna M. Schulz, Stefan F. Lichtenthaler, Stephan A. Müller
Publikováno v:
The Journal of Cell Biology
The journal of cell biology 211(3), 553-567 (2015). doi:10.1083/jcb.201503128
The journal of cell biology 211(3), 553-567 (2015). doi:10.1083/jcb.201503128
Cdc42 control of actin dynamics keeps DCs in an immature state, and loss of Cdc42 activity facilitates secretion and rapid up-regulation of intracellular molecules to the cell surface, which shows that Cdc42 contributes to DC immunogenicity by regula