Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna M Scarborough"'
Autor:
Anna M Scarborough, Juliana N Flaherty, Olga V Hunter, Kuanqing Liu, Ashwani Kumar, Chao Xing, Benjamin P Tu, Nicholas K Conrad
Publikováno v:
eLife, Vol 10 (2021)
S-adenosylmethionine (SAM) is the methyl donor for nearly all cellular methylation events. Cells regulate intracellular SAM levels through intron detention of MAT2A, the only SAM synthetase expressed in most cells. The N6-adenosine methyltransferase
Externí odkaz:
https://doaj.org/article/ac2b0adbe78347f28a8d8a053ebe0d0d
Autor:
Anne M. Devlin, Ashutosh Shukla, Julio C. Ruiz, Spencer D. Barnes, Ashwin Govindan, Olga V. Hunter, Anna M. Scarborough, Iván D’Orso, Nicholas K. Conrad
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The PNUTS-PP1 complex directly binds to RNA, and interacts with polymerase II and RNA processing factors to control transcriptional elongation rates and slow polymerase II after polyadenylation sites to promote termination. Using a genome-wide CRISPR
Externí odkaz:
https://doaj.org/article/c1f1e4399fcb427bafd71414e6943423
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2537
Intron retention (IR) regulates gene expression to control fundamental biological processes like metabolism, differentiation, and cell cycle. Despite a wide variety of genes controlled by IR, few techniques are available to identify regulators of IR
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b64198fd84b5d56d9fe648d86b0f5c
https://doi.org/10.1007/978-1-0716-2521-7_16
https://doi.org/10.1007/978-1-0716-2521-7_16
Autor:
Anna M. Scarborough, Chao Xing, Juliana N Flaherty, Nicholas K. Conrad, Kuanqing Liu, Benjamin P. Tu, Ashwani Kumar, Olga V. Hunter
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
SUMMARYS-adenosylmethionine (SAM) is the methyl donor for nearly all cellular methylation events. Cells regulate intracellular SAM levels through intron detention of the MAT2A RNA, which encodes only SAM synthetase expressed in most cells. The N6-ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78a47be38b4a248254d70d67f6f85d6
https://doi.org/10.1101/2020.11.12.380626
https://doi.org/10.1101/2020.11.12.380626
Autor:
Nicholas K. Conrad, Ping Wang, Katelyn A. Doxtader, Dahee Seo, Yunsun Nam, Anna M. Scarborough
Publikováno v:
Molecular Cell. 71:1001-1011.e4
S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N6-methyladenosine (m6A) methyltransferase METTL16 controls SAM homeostasis by regulating the abundance of SAM synthetase MAT2A