Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Anna M G Pasmooij"'
Autor:
Noa Rosenberg, Sibren van den Berg, Nina N. Stolwijk, Bart A. W. Jacobs, Hendrika C. Post, Anna M. G. Pasmooij, Saco J. de Visser, Carla E. M. Hollak
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Novel or repurposed medicines for rare diseases often emerge from fundamental research or empirical findings in academia. However, researchers may be insufficiently aware of the possibilities and requirements to bring novel medicinal trea
Externí odkaz:
https://doaj.org/article/b95f30a494ad44cca6e4f96a3d519b80
Autor:
Marijn Muurling, Anna M G Pasmooij, Ivan Koychev, Dora Roik, Lutz Froelich, Emilia Schwertner, Dorota Religa, Carla Abdelnour, Mercè Boada, Monica Almici, Samantha Galluzzi, Sandra Cardoso, Alexandre de Mendonça, Andrew P Owens, Sajini Kuruppu, Martha Therese Gjestsen, Ioulietta Lazarou, Mara Gkioka, Magda Tsolaki, Ana Diaz, Dianne Gove, Pieter Jelle Visser, Dag Aarsland, Federica Lucivero, Casper de Boer, RADAR-AD Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294797 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0285807.].
Externí odkaz:
https://doaj.org/article/bd39a7038b4346209d0f2bc37f15046c
Autor:
Marijn Muurling, Anna M G Pasmooij, Ivan Koychev, Dora Roik, Lutz Froelich, Emilia Schwertner, Dorota Religa, Carla Abdelnour, Mercè Boada, Monica Almici, Samantha Galluzzi, Sandra Cardoso, Alexandre de Mendonça, Andrew P Owens, Sajini Kuruppu, Martha Therese Gjestsen, Ioulietta Lazarou, Mara Gkioka, Magda Tsolaki, Ana Diaz, Dianne Gove, Pieter Jelle Visser, Dag Aarsland, Federica Lucivero, Casper de Boer, RADAR-AD Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0285807 (2023)
IntroductionClinical research with remote monitoring technologies (RMTs) has multiple advantages over standard paper-pencil tests, but also raises several ethical concerns. While several studies have addressed the issue of governance of big data in c
Externí odkaz:
https://doaj.org/article/192ad7c5d4424e03a291c8937325bef4
Autor:
Jorn Mulder, Odile C. van Stuijvenberg, Paula B. van Hennik, Emile E. Voest, Anna M. G. Pasmooij, Violeta Stoyanova-Beninska, Anthonius de Boer
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
There are currently four anti-cancer medicinal products approved for a tissue-agnostic indication. This is an indication based on a common biological characteristic rather than the tissue of origin. To date, the regulatory experience with tissue-agno
Externí odkaz:
https://doaj.org/article/bef9992941e84c2bb5b56da3c1c101f1
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
With the implementation of the new EU regulation on in vitro diagnostics (IVDR) in May 2022, notified bodies will be required to assess Companion Diagnostics (CDx). The EMA and national medicines agencies will be consulted on the performance and safe
Externí odkaz:
https://doaj.org/article/c2e08cea09924139807f458c866e210c
Autor:
Jorn Mulder, Robin Verjans, Ciska Verbaanderd, Elias Pean, Just Weemers, Hubert G. M. Leufkens, Francesco Pignatti, Anthonius de Boer, Emile E. Voest, Violeta V. Stoyanova-Beninska, Anna M. G. Pasmooij
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
After marketing authorisation, the development of a medicinal product often continues with studies investigating new therapeutic indications. Positive results can potentially lead to changes to the terms of the marketing authorisation, such as an ext
Externí odkaz:
https://doaj.org/article/77724e08c1d94a20bfe36bcf8b6bb0ba
Autor:
Jorn Mulder, Tobias van Rossum, Segundo Mariz, Armando Magrelli, Anthonius de Boer, Anna M. G. Pasmooij, Violeta Stoyanova-Beninska
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Pancreatic cancer has a dismal prognosis and only a few treatment options are available. In the European Union, pancreatic cancer classifies as a rare disease, allowing drug developers to apply for orphan medicinal product (OMP) designation. The aim
Externí odkaz:
https://doaj.org/article/06e89c99016b4cef9deedbbd3ea837b9
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2118 (2022)
Revertant mosaicism (RM) is the intriguing phenomenon in which nature itself has successfully done what medical science is so eagerly trying to achieve: correcting the effect of disease-causing germline variants and thereby reversing the disease phen
Externí odkaz:
https://doaj.org/article/8374ccc4e3694205a936d532872616e9
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Aims: Recently, the use of novel remote monitoring technologies (RMTs) in trials has gained much interest. To facilitate regulatory learning, we evaluated qualification opinions (QOs) and advices (QAs) and scientific advices (SAs) of the Committee fo
Externí odkaz:
https://doaj.org/article/b50076dba02148bf9c3de580202c72f0
Autor:
Marko J, Kallio, Viktoriia, Starokozhko, Eleonora, Agricola, Manja, Burggraf, Anne, Heß, Wolfgang, Ballensiefen, Wiebke, Löbker, Yoana, Nuevo, Anna M G, Pasmooij, Peter G M, Mol
Publikováno v:
Clinical Pharmacology and Therapeutics, 113(2), 349-359. Nature Publishing Group
Important discoveries by academic drug developers hold the promise of bringing innovative treatments that address unmet medical needs to the market. However, the drug development process has proved to be challenging and demanding for academic researc