Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Anna M Barron"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1869-1870 (2024)
Externí odkaz:
https://doaj.org/article/61914c02121f40db86a7fb07aaf57c55
Publikováno v:
eLife, Vol 10 (2021)
Brain microglia and border-associated macrophages (BAMs) display distinct spatial, developmental, and phenotypic features. Although at steady state, the origins of distinct brain macrophages are well-documented, the dynamics of their replenishment in
Externí odkaz:
https://doaj.org/article/94981eef302b43279a32785b3e375d69
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78554 (2013)
Multiple factors of metabolic syndrome have been implicated in the pathogenesis of Alzheimer's disease (AD), including abdominal obesity, insulin resistance, endocrine dysfunction and dyslipidemia. High fat diet, a common experimental model of obesit
Externí odkaz:
https://doaj.org/article/35a84f488a744a46b3c2ec354b03df2d
Autor:
Lauren H. Fairley, Naruhiko Sahara, Ichio Aoki, Bin Ji, Tetsuya Suhara, Makoto Higuchi, Anna M. Barron
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background The translocator protein (TSPO) has been identified as a positron emission tomography (PET)-visible biomarker of inflammation and promising immunotherapeutic target for the treatment of Alzheimer’s disease (AD). While TSPO ligan
Externí odkaz:
https://doaj.org/article/6cdb02ac955b4c3c9837021740adfdb6
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Natural products remain a crucial source of drug discovery for accessible and affordable solutions for healthy aging. Centella asiatica (L.) Urb. (CA) is an important medicinal plant with a wide range of ethnomedicinal uses. Past in vivo and in vitro
Externí odkaz:
https://doaj.org/article/1436b8a3ec5d4dd098d24ec2cb2168e6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Alzheimer’s disease (AD) is an age-associated terminal neurodegenerative disease with no effective treatments. Dysfunction of innate immunity is implicated in the pathogenesis of AD, with genetic studies supporting a causative role in the disease.
Externí odkaz:
https://doaj.org/article/9cfdabe703be492591a4dbf0a9234fa7
Autor:
Lauren H. Fairley, Kei Onn Lai, Jia Hui Wong, Wei Jing Chong, Anselm Salvatore Vincent, Giuseppe D’Agostino, Xiaoting Wu, Roshan R. Naik, Anusha Jayaraman, Sarah R. Langley, Christiane Ruedl, Anna M. Barron
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Microglial phagocytosis is an energetically demanding process that plays a critical role in the removal of toxic protein aggregates in Alzheimer’s disease (AD). Recent evidence indicates that a switch in energy production from mitochondrial respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a4281071ab4b6c9a2246c31fee872c
https://doi.org/10.1073/pnas.2209177120
https://doi.org/10.1073/pnas.2209177120
Autor:
Makoto Higuchi, Lauren H. Fairley, Tetsuya Suhara, Naruhiko Sahara, Ichio Aoki, Bin Ji, Anna M. Barron
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background The translocator protein (TSPO) has been identified as a positron emission tomography (PET)-visible biomarker of inflammation and promising immunotherapeutic target for the treatment of Alzheimer’s disease (AD). While TSPO ligands have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa3b8fee2b4c970cdf93ed813bc71f9
https://doaj.org/article/6cdb02ac955b4c3c9837021740adfdb6
https://doaj.org/article/6cdb02ac955b4c3c9837021740adfdb6
Publikováno v:
Molecular Neurobiology. 58:550-563
Pharmacological studies have implicated the translocator protein (TSPO) in the regulation of complex behaviors including anxiety and depression, effects thought to be mediated by increased synthesis of neuroactive steroid hormones. However, TSPO func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929710618963f9c66b8c029e4700eb3e
https://doi.org/10.1007/s12035-020-02136-5
https://doi.org/10.1007/s12035-020-02136-5
Autor:
Julian L, Goggi, Siddesh, Hartimath, Shivashankar, Khanapur, Boominathan, Ramasamy, Jun Rong, Tang, Peter, Cheng, Anna M, Barron, Hideo, Tsukada, Edward G, Robins
Publikováno v:
Contrast mediamolecular imaging. 2022
Browning of white adipose tissue (WAT) into beige adipocytes has been proposed as a strategy to tackle the ongoing obesity epidemic. Thermogenic stimuli have been investigated with the aim of converting existing white adipose tissue, primarily used f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25c12a2405b01c87bbe2101b393d063d
https://pubmed.ncbi.nlm.nih.gov/35694709
https://pubmed.ncbi.nlm.nih.gov/35694709