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Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 103:503-518
Encapsulation of cells in biocompatible polymer matrices represents a powerful tool for cell-based therapies and therapeutic delivery systems. This technology has successfully been used to deliver pancreatic islets to humans for the treatment of Type
Autor:
Robert B. Elliott, Lee Law, Anna Louise Hillberg, Janice B. B. Lam, Olga Garkavenko, Kalyani Kathirgamanathan
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 101(2)
DIABECELL® capsules comprise an inner core of alginate (Alg) coated with a polycationic polymer, poly-L-ornithine (PLO), designed as a stabilizing agent for strengthening the capsule wall, which is masked by an outer layer of biocompatible Alg. Thes